Probe-specific mixed-model approach to detect copy number differences using multiplex ligation-dependent probe amplification (MLPA)

BMC Bioinformatics

Volumn 9, Issue , 2008, Pages

  González, Juan R ^a,b,c   Carrasco, Josep L ^c   Armengol, Lluís ^b,d   Villatoro, Sergi ^b,d   Jover, Lluís ^c   Yasui, Yutaka ^e   Estivill, Xavier ^b,d  

^a CENTRE FOR RESEARCH IN ENVIRONMENTAL EPIDEMIOLOGY CREAL   (Spain)

^b CIBER EPIDEMIOLOGÍA Y SALUD PÚBLICA CIBERESP   (Spain)

^c UNIVERSITY OF BARCELONA   (Spain)

^d CENTRE FOR GENOMIC REGULATION CRG   (Spain)

^e UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

COPY-NUMBER ALTERATIONS; ERROR VARIABILITY; ITERATIVE REGRESSION; PROBE AMPLIFICATION; SENSITIVITY AND SPECIFICITY; SIMULATION STUDIES; STATISTICAL SIGNIFICANCE; TOLERANCE INTERVAL;

PROBES;

ITERATIVE METHODS;

DNA;

ARTICLE; AUTISM; COMPUTER SIMULATION; CONTROLLED STUDY; DIGEORGE SYNDROME; GENE AMPLIFICATION; GENE IDENTIFICATION; GENE NUMBER; GENETIC MODEL; GENETIC VARIABILITY; HUMAN; MATHEMATICAL COMPUTING; MIXED MODEL; MULIPLEX LIGATION DEPENDENT PROBE AMPLIFICATION; NONLINEAR REGRESSION ANALYSIS; NONLINEAR SYSTEM; PRADER WILLI SYNDROME; SENSITIVITY AND SPECIFICITY; STATISTICAL SIGNIFICANCE; BREAST TUMOR; CONFIDENCE INTERVAL; DNA PROBE; GENE DOSAGE; GENETIC MARKER; GENETIC PREDISPOSITION; GENETIC PROCEDURES; GENETICS; POLYMERASE CHAIN REACTION; PREDICTION AND FORECASTING; REFERENCE VALUE; SINGLE BLIND PROCEDURE; STANDARD; STATISTICAL MODEL; STATISTICS;

AUTISTIC DISORDER; BREAST NEOPLASMS; CONFIDENCE INTERVALS; DIGEORGE SYNDROME; DNA PROBES; GENE DOSAGE; GENETIC MARKERS; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LINEAR MODELS; MOLECULAR PROBE TECHNIQUES; POLYMERASE CHAIN REACTION; PRADER-WILLI SYNDROME; PREDICTIVE VALUE OF TESTS; REFERENCE STANDARDS; REFERENCE VALUES; SINGLE-BLIND METHOD; STOCHASTIC PROCESSES; VARIATION (GENETICS);

EID: 48549085440     PISSN: None     EISSN: 14712105     Source Type: Journal    
DOI: 10.1186/1471-2105-9-261     Document Type: Article

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