JTE-607, an inflammatory cytokine synthesis inhibitor, attenuates ischemia/reperfusion-induced renal injury by reducing neutrophil activation in rats

Journal of Bioscience and Bioengineering

Volumn 106, Issue 1, 2008, Pages 22-26

  Asaga, Takehiko ^a   Ueki, Masaaki ^a   Chujo, Kousuke ^a   Taie, Satoshi ^a  

^a KAGAWA UNIVERSITY   (Japan)

Author keywords

cytokine induced neutrophil chemoattractant 1 (CINC 1); ischemia reperfusion; JTE 607; kidney; neutrophil

Indexed keywords

BIOASSAY; NITROGEN; NONMETALS; RATS; SURGERY; TRANSPLANTATION (SURGICAL); UREA;

BLOOD UREA; CHEMOATTRACTANT; CONTROL GROUP; CYTOKINE; CYTOKINE-INDUCED NEUTROPHIL CHEMOATTRACTANT-1 (CINC-1); ENDOTOXIC SHOCK; INFLAMMATORY CYTOKINES; ISCHEMIA/REPERFUSION; JTE-607; KIDNEY; MOUSE MODELS; MYELOPEROXIDASE; NEUTROPHIL; POTENT INHIBITORS; RENAL FAILURE; RENAL INJURY; RENAL TRANSPLANTATION; SERUM CONCENTRATIONS; WISTAR RATS;

HEALTH;

CREATININE; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT 1; CYTOKINE RECEPTOR ANTAGONIST; JTE 607; MANNITOL; MYELOPEROXIDASE; UNCLASSIFIED DRUG;

ACUTE KIDNEY TUBULE NECROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG INHIBITION; HISTOPATHOLOGY; ISCHEMIA; KIDNEY FAILURE; KIDNEY FUNCTION; KIDNEY INJURY; LEUKOCYTE ACTIVATION; MALE; NONHUMAN; RAT; REPERFUSION INJURY; SEPTIC SHOCK; UREA NITROGEN BLOOD LEVEL;

ANIMALS; CYTOKINES; KIDNEY DISEASES; MALE; NEUTROPHIL ACTIVATION; PHENYLALANINE; PIPERAZINES; RATS; REPERFUSION INJURY;

RATTUS; RATTUS NORVEGICUS;

EID: 48449106067     PISSN: 13891723     EISSN: None     Source Type: Journal    
DOI: 10.1263/jbb.106.22     Document Type: Article

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