Editorial: Is BAFF the murderer in lupus?

Lupus

Volumn 17, Issue 7, 2008, Pages 613-614

  Youinou, P ^a  

^a UNIVERSITÉ DE BRETAGNE OCCIDENTALE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

B CELL ACTIVATING FACTOR; ANTIBODY;

ANTIGEN ANTIBODY COMPLEX; APOPTOSIS; B LYMPHOCYTE; EDITORIAL; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIUM CELL; HUMAN; PRIORITY JOURNAL; SYSTEMIC LUPUS ERYTHEMATOSUS; T LYMPHOCYTE; UPREGULATION; ANIMAL; IMMUNOLOGY; MOUSE;

ANIMALS; ANTIBODIES; B-CELL ACTIVATING FACTOR; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MICE;

EID: 48349137297     PISSN: 09612033     EISSN: None     Source Type: Journal    
DOI: 10.1177/0961203308092164     Document Type: Editorial

References (20)

1. D'Cruz, DP, Khamashta, MA, Hughes, GR. Systemic lupus erythematosus. Lancet 2007; 369: 587-596.
2. Lipsky, PE, Systemic lupus erythematosus: an autoimmune disease of B cell hyperactivity. Nat Immunol 2001; 2: 764-766.
3. Youinou, P, Daridon, C, Steinfeld, S, Pers, JO. A case for B cells in the pathogenesis of Sjögren's syndrome. Trends Immunol (in press).
4. Martinez-Gamboa, L, Brezinschek, HP, Burmester, GR, Dörner, T. Immunopathologic role of B lymphocytes in rheumatoid arthritis: rationale of B cell-directed therapy. Autoimmun Rev 2006; 5: 437-442.
5. Mackay, F, Silveira, PA, Brink, R. B cells and the BAFF/APRIL axis: fast-forward on autoimmunity and signaling. Curr Opin Immunol 2007; 19: 327-336.
6. Daridon, C, Youinou, P, Pers, JO. BAFF, APRIL, TWE-PRIL: Who's who. Autoimmun Rev 2008; 7: 267-271.
7. Bossen, C, Schneider, P. BAFF, APRIL and their receptors: structure, function and signaling. Semin Immunol 2006; 18: 263-275.
8. Daridon, C, Devauchelle, V, Hutin, P, et al. Aberrant expression of BAFF by B lymphocytes infiltrating the salivary glands of patients with primary Sjögren's syndrome. Arthritis Rheum 2007; 56: 1134-1144.
9. Sutherland, AP, Ng, LG, Fletcher, CA, et al. BAFF augments certain Thl-associated inflammatory responses. J Immunol 2005; 174: 5537-5544.
10. Mackay, F, Woodcock, SA, Lawton, P, et al. Mice transgenic for BAFF developlymphocytic disorders along with autoimmune manifestations. J Exp Med 1999; 190: 1697-1710.
11. Groom, J, Railed, SL, Cutler, AH, et al. Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren's syndrome. J Clin Invest 2002; 109: 59-68.
12. Batten, M, Groom, J, Cachero, TG, et al. BAFF mediates survival of peripheral immature B lymphocytes. J Exp Med 2000; 192: 1453-1466.
13. Groom, JR, Fletcher, CA, Walters, SN, et al. BAFF and MyD88 signals promote a lupus like disease independent of T cells. J Exp Med 2007; 204: 1959-1971.
14. Zouali, M. Receptor editing and receptor revision in rheumatic autoimmune diseases. Trends Immunol 2008; 29: 103-109.
15. Rochas, C, Hillion, S, Saraux, A, et al. Transmembrane BAFF from rheumatoid synoviocytes requires IL-6 to induce the expression of RAGs in B lymphocytes (submitted for publication).
16. Pers, JO, Daridon, C, Devauchelle, V, et al. BAFF overexpression is associated with autoantibody production in autoimmune diseases. Ann N Y Acad Sci 2005; 1050: 34-39.
17. Pers, JO, Devauchelle, V, Daridon, C, et al. BAFF-modulated repopulation of B lymphocytes in the blood and salivary glands of rituximab-treated patients with Sjögren's syndrome. Arthritis Rheum 2007; 56: 1464-1477.
18. Zhang, J, Roschke, V, Baker, RP, et al. Cutting edge: a role for B lymphocyte stimulator in systemic lupus erythematosus. J Immunol 2001; 166: 6-10.
19. Stohl, W. Targeting B lymphocyte stimulator in systemic lupus erythematosus and other autoimmune rheumatic disorders. Expert Opin Ther Targets 2004; 8: 177-189.
20. Le Pottier, L, Bendaoud, B, Dueymes, M, et al. BAFF, a new target for intravenous immunoglobulin in autoimmunity and cancer. J Clin Immunol 2007; 27: 257-265.