-
1
-
-
33749263031
-
-
Bonate, P.L.; Arthaud, L.; Cantrell, W.R., Jr.; Stephenson, K.; Secrist III, J.A.; Weitman, S. Discovery and development of clofarabine: a nucleoside analogue for treating cancer. Nat. Rev. Dru. Discov. 2006, 5, 855-863.
-
Bonate, P.L.; Arthaud, L.; Cantrell, W.R., Jr.; Stephenson, K.; Secrist III, J.A.; Weitman, S. Discovery and development of clofarabine: a nucleoside analogue for treating cancer. Nat. Rev. Dru. Discov. 2006, 5, 855-863.
-
-
-
-
2
-
-
25144513582
-
Recent highlights in the development of new antiviral drugs
-
De Clercq, E. Recent highlights in the development of new antiviral drugs. Curr. Opin. Microbiol. 2005, 8, 552-560.
-
(2005)
Curr. Opin. Microbiol
, vol.8
, pp. 552-560
-
-
De Clercq, E.1
-
3
-
-
0036453665
-
Pharmacological and biological aspects of basic research on nucleoside-based reverse transcriptase inhibitors
-
Macchi, B.; Mastino, A. Pharmacological and biological aspects of basic research on nucleoside-based reverse transcriptase inhibitors. Pharmacol. Res. 2002, 46, 473-482.
-
(2002)
Pharmacol. Res
, vol.46
, pp. 473-482
-
-
Macchi, B.1
Mastino, A.2
-
4
-
-
11144233697
-
HIV reverse transcriptase structures: Designing new inhibitors and understanding mechanisms of drug resistance
-
Ren, J.; Stammers, D.K. HIV reverse transcriptase structures: designing new inhibitors and understanding mechanisms of drug resistance. Trend. Pharm. Sci. 2005, 26, 4-7.
-
(2005)
Trend. Pharm. Sci
, vol.26
, pp. 4-7
-
-
Ren, J.1
Stammers, D.K.2
-
5
-
-
0014127726
-
The role of the 5′ -hydroxyl group of adenosine in determining substrate specificity for adenosine deaminase
-
Bloch, A.; Robins, M.J.; McCarthy, J.R., Jr. The role of the 5′ -hydroxyl group of adenosine in determining substrate specificity for adenosine deaminase. J. Med. Chem. 1967, 10, 908-912.
-
(1967)
J. Med. Chem
, vol.10
, pp. 908-912
-
-
Bloch, A.1
Robins, M.J.2
McCarthy Jr., J.R.3
-
6
-
-
0026472745
-
Synthesis of thymine nucleosides derived from 1-deoxy-D-psicofuranose
-
Faivre-Buet, V.; Grouiller, A.; Descotes, G. Synthesis of thymine nucleosides derived from 1-deoxy-D-psicofuranose. Nucleos. Nucleot. Nucl. 1992, 11, 1651-1660.
-
(1992)
Nucleos. Nucleot. Nucl
, vol.11
, pp. 1651-1660
-
-
Faivre-Buet, V.1
Grouiller, A.2
Descotes, G.3
-
7
-
-
0028355372
-
A ribonolactone-based approach to the synthesis of 1′-carbon-substituted thymine ribonucleosides
-
Hayakawa, H.; Miyazawa, M.; Tanaka, H.; Miyasaka, T. A ribonolactone-based approach to the synthesis of 1′-carbon-substituted thymine ribonucleosides. Nucleos. Nucleot. Nucl. 1994, 13, 297-308.
-
(1994)
Nucleos. Nucleot. Nucl
, vol.13
, pp. 297-308
-
-
Hayakawa, H.1
Miyazawa, M.2
Tanaka, H.3
Miyasaka, T.4
-
8
-
-
0035354786
-
An efficient method for the preparation of 1′alpha-branched-chain sugar pyrimidine ribonucleosides from uridine: The first conversion of a natural nucleoside into 1′ -substituted ribonucleosides
-
Kodama, T.; Shuto, S.; Nomura, M.; Matsuda, A. An efficient method for the preparation of 1′alpha-branched-chain sugar pyrimidine ribonucleosides from uridine: the first conversion of a natural nucleoside into 1′ -substituted ribonucleosides. Chem. Eur. J. 2001, 7, 2332-2340.
-
(2001)
Chem. Eur. J
, vol.7
, pp. 2332-2340
-
-
Kodama, T.1
Shuto, S.2
Nomura, M.3
Matsuda, A.4
-
9
-
-
0037075782
-
Ribose-modified nucleosides as ligands for adenosine receptors: Synthesis, conformational analysis, and biological evaluation of 1′-C-methyl adenosine analogues
-
Cappellacci, L.; Barboni, G.; Palmieri, M.; Pasqualini, M.; Grifantini, M.; Costa, B.; Martini, C.; Franchetti, P. Ribose-modified nucleosides as ligands for adenosine receptors: synthesis, conformational analysis, and biological evaluation of 1′-C-methyl adenosine analogues. J. Med. Chem. 2002, 45, 1196-1202.
-
(2002)
J. Med. Chem
, vol.45
, pp. 1196-1202
-
-
Cappellacci, L.1
Barboni, G.2
Palmieri, M.3
Pasqualini, M.4
Grifantini, M.5
Costa, B.6
Martini, C.7
Franchetti, P.8
-
10
-
-
48349108134
-
-
Sommadossi, J.-P.; Gosselin, G.; Storer, R.; Egan, J. PCT Int. Appl. 2006, Application: WO 2005-US34786 20050926. Priority: US 2004-613085 20040924.
-
Sommadossi, J.-P.; Gosselin, G.; Storer, R.; Egan, J. PCT Int. Appl. 2006, Application: WO 2005-US34786 20050926. Priority: US 2004-613085 20040924.
-
-
-
-
11
-
-
8144230566
-
Activity of adenosine deaminase (ADA) and adenylate deaminase (AMPDA) towards 6-chloropurine nucleosides modified in the ribose moiety
-
Ciuffreda, P.; Buzzi, B.; Alessandrini, L.; Santaniello, E. Activity of adenosine deaminase (ADA) and adenylate deaminase (AMPDA) towards 6-chloropurine nucleosides modified in the ribose moiety. Eur. J. Org. Chem. 2004, 4405-4409.
-
(2004)
Eur. J. Org. Chem
, pp. 4405-4409
-
-
Ciuffreda, P.1
Buzzi, B.2
Alessandrini, L.3
Santaniello, E.4
-
12
-
-
36949019362
-
2′,3′- Isopropylidene group,amolecular scaffoldtostudy the activityofadenosine and adenylatedeaminaseonadenosine analogues modified in the ribose moiety
-
Ciuffreda, P.; Alessandrini, L.; Santaniello,E. 2′,3′- Isopropylidene group,amolecular scaffoldtostudy the activityofadenosine and adenylatedeaminaseonadenosine analogues modified in the ribose moiety. Nucleos. Nucleot. Nucl. 2007, 26, 1311-1313.
-
(2007)
Nucleos. Nucleot. Nucl
, vol.26
, pp. 1311-1313
-
-
Ciuffreda, P.1
Alessandrini, L.2
Santaniello, E.3
-
13
-
-
0025044217
-
Aconvenient large scale synthesis of protected D-ribonolactone from D-ribose
-
Kaskar, B.; Heise, G.L.; Michalak, R.S.; Vishnuvajjala, B.R.Aconvenient large scale synthesis of protected D-ribonolactone from D-ribose. Synthesis 1990, 1031-1032.
-
(1990)
Synthesis
, pp. 1031-1032
-
-
Kaskar, B.1
Heise, G.L.2
Michalak, R.S.3
Vishnuvajjala, B.R.4
-
14
-
-
33745738179
-
A concise, efficient and production-scale synthesis of a protected L-lyxonolactone derivative: An important aldonolactone core
-
Batra, H.; Moriarty, R.M.; Penmasta, R.; Sharma, V.; Stanciuc, G.; Staszewski, J.P.; Tuladhar, S.M.; Walsh, D.A. A concise, efficient and production-scale synthesis of a protected L-lyxonolactone derivative: an important aldonolactone core. Org. Process Res. Dev. 2006, 10, 484-486.
-
(2006)
Org. Process Res. Dev
, vol.10
, pp. 484-486
-
-
Batra, H.1
Moriarty, R.M.2
Penmasta, R.3
Sharma, V.4
Stanciuc, G.5
Staszewski, J.P.6
Tuladhar, S.M.7
Walsh, D.A.8
-
15
-
-
0026077816
-
A new synthesis of D-ribonolactone from D-ribose by pyridinium chlorochromate oxidation
-
Liu, D.; Caperelli, C.A. A new synthesis of D-ribonolactone from D-ribose by pyridinium chlorochromate oxidation. Synthesis 1991, 933-934.
-
(1991)
Synthesis
, pp. 933-934
-
-
Liu, D.1
Caperelli, C.A.2
-
17
-
-
0028470907
-
Tetra-n-propylammonium tetra-oxoruthenate(VII): A reagent of choice for the oxidation of diversely protected glycopyranoses and glycofuranoses to lactones
-
Benhaddou, R.; Czernecki, S.; Farid, W.; Ville, G.; Xie, J.; Zegar, A. Tetra-n-propylammonium tetra-oxoruthenate(VII): a reagent of choice for the oxidation of diversely protected glycopyranoses and glycofuranoses to lactones. Carbohydr. Res. 1994, 260, 243-250.
-
(1994)
Carbohydr. Res
, vol.260
, pp. 243-250
-
-
Benhaddou, R.1
Czernecki, S.2
Farid, W.3
Ville, G.4
Xie, J.5
Zegar, A.6
-
18
-
-
0001403962
-
-
Wood, H.B.; Diehl, H.W.; Fletcher, H.G. Some products arising from the condensation of D-ribose with benzaldehyde. 2,3-O-benzylidene- β-D-ribofuranose and di-(2,3-O-benzylidene-D- ribofuranose)-1,5′:1′,5-dianhydride. J. Am. Chem. Soc. 1956, 78, 4715-4717.
-
Wood, H.B.; Diehl, H.W.; Fletcher, H.G. Some products arising from the condensation of D-ribose with benzaldehyde. 2,3-O-benzylidene- β-D-ribofuranose and di-(2,3-O-benzylidene-D- ribofuranose)-1,5′:1′,5-dianhydride. J. Am. Chem. Soc. 1956, 78, 4715-4717.
-
-
-
-
19
-
-
26844458660
-
Configurational and conformational studies on some benzylidene derivatives of D-ribose and di-β-D- ribofuranose 1-5′:1′ ,5-dianhydride
-
Grindley, T.B.; Szarek, W.A. Configurational and conformational studies on some benzylidene derivatives of D-ribose and di-β-D- ribofuranose 1-5′:1′ ,5-dianhydride. Carbohydrate Res. 1972, 25, 187-195.
-
(1972)
Carbohydrate Res
, vol.25
, pp. 187-195
-
-
Grindley, T.B.1
Szarek, W.A.2
-
20
-
-
33947476003
-
2,3,5-tri-O-benzyl-D-ribosyl and L-arabinosyl bromides
-
Barker, R.; Fletcher, H.G. 2,3,5-tri-O-benzyl-D-ribosyl and L-arabinosyl bromides. J. Org. Chem. 1961, 26, 4605-4609.
-
(1961)
J. Org. Chem
, vol.26
, pp. 4605-4609
-
-
Barker, R.1
Fletcher, H.G.2
-
21
-
-
3142736550
-
Synthetic methodologies for C-nucleosides
-
Wu, Q.; Simons, C. Synthetic methodologies for C-nucleosides. Synthesis 2004, 1533-1553.
-
(2004)
Synthesis
, pp. 1533-1553
-
-
Wu, Q.1
Simons, C.2
-
22
-
-
33845471552
-
Syntheses of hydroxy ketones from lactones
-
Cavicchioli, S.; Savoia, D.; Trombini, C.; Umani-Ronchi, A. Syntheses of hydroxy ketones from lactones. J. Org. Chem. 1984, 49, 1246-1251.
-
(1984)
J. Org. Chem
, vol.49
, pp. 1246-1251
-
-
Cavicchioli, S.1
Savoia, D.2
Trombini, C.3
Umani-Ronchi, A.4
-
23
-
-
0033582498
-
Chiral 1,4-dicarbonyl-2,3-O-isopropylidene derivatives
-
Rodriguez, J.B. Chiral 1,4-dicarbonyl-2,3-O-isopropylidene derivatives. Rapid racemization on standing. Tetrahedron 1999, 55, 2157-2170.
-
(1999)
Rapid racemization on standing. Tetrahedron
, vol.55
, pp. 2157-2170
-
-
Rodriguez, J.B.1
-
24
-
-
0023807103
-
The synthesis of "C-O-N" analogues of nucleosides via the Mitsunobu reaction
-
Grochowski, E.; Stepowska, H. The synthesis of "C-O-N" analogues of nucleosides via the Mitsunobu reaction. Synthesis 1988, 795-797.
-
(1988)
Synthesis
, pp. 795-797
-
-
Grochowski, E.1
Stepowska, H.2
-
25
-
-
0001636810
-
Differentially Protected ribofuranoid glycals
-
Cheng, J.C.-Y.; Hacksell, U.; Daves, G.D., Jr. Differentially Protected ribofuranoid glycals. J. Org. chem. 1985, 50, 2778-2780.
-
(1985)
J. Org. chem
, vol.50
, pp. 2778-2780
-
-
Cheng, J.C.-Y.1
Hacksell, U.2
Daves Jr., G.D.3
-
26
-
-
0001858114
-
3-desoxyhex-2-enono-1,4- lactone aus D-hexofuran(osid)-urono-6,3-lactonen
-
Timpe, W.; Dax, K.; Wolf, N.; Weidermann, H. 3-desoxyhex-2-enono-1,4- lactone aus D-hexofuran(osid)-urono-6,3-lactonen. Carbohydrate Res. 1975, 39, 53-60.
-
(1975)
Carbohydrate Res
, vol.39
, pp. 53-60
-
-
Timpe, W.1
Dax, K.2
Wolf, N.3
Weidermann, H.4
-
27
-
-
0030767989
-
Benzylation of aldonolactones with benzyl trichloroacetimidate
-
Jensen, H.S.; Limberg, G.; Pedersen, C. Benzylation of aldonolactones with benzyl trichloroacetimidate. Carbohydrate Res. 1997, 302, 109-112.
-
(1997)
Carbohydrate Res
, vol.302
, pp. 109-112
-
-
Jensen, H.S.1
Limberg, G.2
Pedersen, C.3
-
28
-
-
0343906844
-
2 mediated conversion of γ, δ, -olefinic alcohols into C-glycosides
-
2 mediated conversion of γ, δ, -olefinic alcohols into C-glycosides. Tetrahedron Lett. 1997, 38, 9051-9054.
-
(1997)
Tetrahedron Lett
, vol.38
, pp. 9051-9054
-
-
Sharma, G.V.M.1
Chander, A.S.2
Krishnudu, K.3
Krishna, R.P.4
|