The efficiency of Viscum album ssp. album and Hypericum perforatum on human immune cells in vitro

Immunopharmacology and Immunotoxicology

Volumn 30, Issue 3, 2008, Pages 519-528

  Fidan, Isil ^a   Ozkan, Semiha ^a   Gurbuz, Ilhan ^a   Yesilyurt, Emine ^a   Erdal, Berna ^a   Yolbakan, Sultan ^a   Imir, Turgut ^a  

^a GAZI UNIVERSITY   (Turkey)

Author keywords

Hypericum perforatum L.; Immune cells; Viscum album L. ssp. album

Indexed keywords

CD16 ANTIGEN; CD56 ANTIGEN; CD69 ANTIGEN; CELL SURFACE MARKER; HYPERICUM PERFORATUM EXTRACT; VISCUM ALBUM EXTRACT;

ANTIFUNGAL ACTIVITY; ARTICLE; CD4+ CD25+ T LYMPHOCYTE; CD8+ CD25+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL ADHESION; CELL CULTURE; CONTROLLED STUDY; CULTURE MEDIUM; DRUG EFFECT; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HYPERICUM PERFORATUM; IMMUNOCOMPETENT CELL; IMMUNOREGULATION; NATURAL KILLER CELL; NEUTROPHIL; NORMAL HUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; VISCUM ALBUM;

ADJUVANTS, IMMUNOLOGIC; ANTIGENS, CD; BACTERIAL ADHESION; CANDIDA ALBICANS; CELLS, CULTURED; EPITHELIAL CELLS; ESCHERICHIA COLI; FLOW CYTOMETRY; HUMANS; HYPERICUM; LEUKOCYTES, MONONUCLEAR; MOUTH MUCOSA; NEUTROPHILS; PHAGOCYTOSIS; PLANT COMPONENTS, AERIAL; PLANT EXTRACTS; VISCUM ALBUM;

HYPERICUM PERFORATUM; VISCUM ALBUM;

EID: 48349109839     PISSN: 08923973     EISSN: 15322513     Source Type: Journal    
DOI: 10.1080/08923970802135286     Document Type: Article

References (22)

1. nd edition. Istanbul: Nobel Tip Kitapevi, 1999.
2. Dorhoi, A.; Dobrean, V.; Zahan, M.; Virag, P. Modulatory effects of several herbal extracts on avian peripheral blood cell immune responses. Phytother. Res. 2006, 20 (5), 352-358.
3. Gurbuz, I.; Ustun, O.; Yesilada, E.; Sezik, E.; Akyurek, N. In vivo gastroprotective effects of five Turkish folk remedies against ethanol-induced lesions. J. Ethnopharmacol. 2002, 83 (3), 241-244.
4. Karagöz, A.; Önay, E.; Arda, N.; Kuru, A. Antiviral potency of Mistletoe (Viscum album ssp. album) extracts against human parainfluenza virus Type 2 in vero cells. Phytother. 2003, 17 (5), 560-562.
5. Yesilada, E.; Deliorman, D.; Ergun, F.; Takaishi, Y.; Ono, Y. Effects of the Turkish species of Viscum album on macrophage-derived cytokines. J. Ethnopharmacol. 1998, 61 (3), 195-200.
6. 2+ mobilization and functional leukocyte responses by hyperforin. Biochem. Pharmacol. 2004, 67 (8), 1531-1539.
7. Butterweck, V.; Schmidt, M. St. John's wort: Role of active compounds for its mechanism of action and efficacy. Wien Med. Wochenschr. 2007, 157(13-14), 356-361.
8. Pabuçcuoǧlu, A.; Konyahoǧlu, S.; Ba6, M.; Meral, G.E. The in vitro effects of Hypericum species on human leukocyte myeloperoxidase activity. J. Ethnopharmacol. 2003, 87(1), 89-92.
9. Yeşilada, E.; Gürbüz, I.; Shibata, H. Screening of Turkish anti-ulcerogenic folk remedies for anti-Helicobacter pylori activity. J. Ethnopharmacol. 1999, 66(3), 289-293.
10. Abbas, A.K.; Lichtman, A.H.. Immunity to microbes. In: Melley J, editor. Cellular and Molecular Immunology. 5th ed. Philadelphia: Elsevier Science, 2003; p. 17.
11. Liu, J.J.; Song, C.W.; Yue, Y.; Duan, C.G.; Yang, J.; He, T.; He, YZ. Quercetin inhibits LPS-induced delay in spontaneous apoptosis and activation of neutrophils. Inflamm. Res. 2005, 54 (12), 500-507.
12. Vidya, K.C.; Mallya, P.S.; Rao, PS. Inhibition of bacterial adhesion by subinhibitory Concentrations of antibiotics. Ind. J. Med. Microbiol. 2005, 23 (2), 102-105.
13. Frank, U.; Engels, I.; Wagner, A.; Lacour, M.; Daschner, F.D. Influence of mistletoe (Viscum album) extracts on phagocytosis/burst activity of human phagocytes. Eur. J. Clin. Microbiol. Infect. Dis. 2003, 22(8), 501-503.
14. Heinzerling, L.; Baehr, V.V.; Liebenthal, C.; Baehr, R.V.; Volk, H.D. Immunologic effector mechanisms of a standardized mistletoe extract on the function of human monocytes and lymphocytes in vitro, ex vivo, and in vivo. J. Clin. Immunol. 2006, 26(4), 347-359.
15. Lee, J.Y.; Kim, J.Y.; Lee, Y.G.; Byeon, S.E.; Kim, B.H.; Rhee, M.H.; Lee, A.; Kwon, M.; Hong, S.; Cho, J.Y. In vitro immunoregulatory effects of Korean mistletoe lectin on functional activation of monocytic and macrophage-like cells. Biol. Pharm. Bull. 2007, 30(11), 2043-2051.
16. Lyu, S.Y.; Park, W.B. Mistletoe Lectin (Viscum album coloratum) modulates proliferation and cytokine expressions in murine aplenocytes. J. Biochem. Mol. Biol. 2006, 39(6), 662-670.
17. Helgason, C.M.; Wieseler, Frank J.L.; Johnson, D.R.; Frank, M.G.; Hendricks, S.E. The effects of St. John's Wort (Hypericum perforatum) on NK cell activity in vitro Immunopharmacol. 2000, 46 (3), 247-251.
18. Zhou, C.; Tabb, M.M.; Sadatrafiei, A.; Grün, F.; Sun, A.; Blumberg, B. Hyperforin, the active component of St. John's wort, induces IL-8 expression in human intestinal epithelial cells via a MAPK-dependent, NF-kappaB-independent pathway. J. Clin. Immunol. 2004, 24(6), 623-636.
19. Schempp, C.M.; Winghoper, B.; Lüdtke, R.; Simon-Haarhaus; B., Schöpf, E.; Simon, J.C. Topical application of St John's wort (Hypericum perforatum L.) and of its metabolite hyperforin inhibits the allostimulatory capacity of epidermal cells. Br. J. Dermatol. 2000,142 (5), 979-984.
20. Lawvere, S.; Mahoney, M.C. St. John's wort. Am. Fam. Physician. 2005, 72, 2249-2254.
21. Gibbons, S.; Ohlendorf, B.; Johnsen, I. The genus Hypericum - A valuable resource of anti-Staphylococcal leads. Fitoterapia 2002, 73 (4), 300-304.
22. Izzo, A.A. Herb-drug interactions: An overview of the clinical evidence. Fund. Clin. Pharmacol. 2005, 19 (1), 1-16.