-
1
-
-
0003083826
-
cDNA for the human beta 2-adrenergic receptor: A protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the receptor for platelet-derived growth factor
-
Kobilka BK, Dixon RA, Frielle T, Dohlman HG, Bolanowski MA, Sigal IS, et al. cDNA for the human beta 2-adrenergic receptor: a protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the receptor for platelet-derived growth factor. Proc Natl Acad Sci U S A 1987; 84: 46-50.
-
(1987)
Proc Natl Acad Sci U S A
, vol.84
, pp. 46-50
-
-
Kobilka, B.K.1
Dixon, R.A.2
Frielle, T.3
Dohlman, H.G.4
Bolanowski, M.A.5
Sigal, I.S.6
-
2
-
-
0029152197
-
Genetic susceptibility to asthma - bronchial hyperresponsiveness coinherited with a major gene for atopy
-
Postma DS, Bleecker ER, Amelung PJ, Holroyd KJ, Xu J, Panhuysen CI, et al. Genetic susceptibility to asthma - bronchial hyperresponsiveness coinherited with a major gene for atopy. N Engl J Med 1995; 333: 894-900.
-
(1995)
N Engl J Med
, vol.333
, pp. 894-900
-
-
Postma, D.S.1
Bleecker, E.R.2
Amelung, P.J.3
Holroyd, K.J.4
Xu, J.5
Panhuysen, C.I.6
-
3
-
-
0023194433
-
Delineation of the intronless nature of the genes for the human and hamster beta 2-adrenergic receptor and their putative promoter regions
-
Kobilka BK, Frielle T, Dohlman HG, Bolanowski MA, Dixon RA, Keller P, et al. Delineation of the intronless nature of the genes for the human and hamster beta 2-adrenergic receptor and their putative promoter regions. J Biol Chem 1987; 262: 7321-7.
-
(1987)
J Biol Chem
, vol.262
, pp. 7321-7327
-
-
Kobilka, B.K.1
Frielle, T.2
Dohlman, H.G.3
Bolanowski, M.A.4
Dixon, R.A.5
Keller, P.6
-
4
-
-
0028850663
-
Genetics of beta2-adrenergic receptor variants in asthma
-
Liggett SB. Genetics of beta2-adrenergic receptor variants in asthma. Clin Exp Allergy 1995; 25 Suppl 2: 89-96.
-
(1995)
Clin Exp Allergy
, vol.25
, Issue.SUPPL. 2
, pp. 89-96
-
-
Liggett, S.B.1
-
5
-
-
0032442150
-
Polymorphisms of the 5′ leader cistron of the human beta2-adrenergic receptor regulate receptor expression
-
McGraw DW, Forbes SL, Kramer LA, Liggett SB. Polymorphisms of the 5′ leader cistron of the human beta2-adrenergic receptor regulate receptor expression. J Clin Invest 1998; 102: 1927-32.
-
(1998)
J Clin Invest
, vol.102
, pp. 1927-1932
-
-
McGraw, D.W.1
Forbes, S.L.2
Kramer, L.A.3
Liggett, S.B.4
-
6
-
-
0028068550
-
Amino-terminal polymorphisms of the human beta 2-adrenergic receptor impart distinct agonist-promoted regulatory properties
-
Green SA, Turki J, Innis M, Liggett SB. Amino-terminal polymorphisms of the human beta 2-adrenergic receptor impart distinct agonist-promoted regulatory properties. Biochemistry 1994; 33: 9414-9.
-
(1994)
Biochemistry
, vol.33
, pp. 9414-9419
-
-
Green, S.A.1
Turki, J.2
Innis, M.3
Liggett, S.B.4
-
7
-
-
0029339086
-
Influence of beta 2-adrenergic receptor genotypes on signal transduction in human airway smooth muscle cells
-
Green SA, Turki J, Bejarano P, Hall IP, Liggett SB. Influence of beta 2-adrenergic receptor genotypes on signal transduction in human airway smooth muscle cells. Am J Respir Cell Mol Biol 1995; 13: 25-33.
-
(1995)
Am J Respir Cell Mol Biol
, vol.13
, pp. 25-33
-
-
Green, S.A.1
Turki, J.2
Bejarano, P.3
Hall, I.P.4
Liggett, S.B.5
-
8
-
-
0034518904
-
Polymorphism of the beta (2) - adrenergic receptor gene and desensitization in human airway smooth muscle
-
Moore PE, Laporte JD, Abraham JH, Schwartzman IN, Yandava CN, Silverman ES, et al. Polymorphism of the beta (2) - adrenergic receptor gene and desensitization in human airway smooth muscle. Am J Respir Crit Care Med 2000; 162: 2117-24.
-
(2000)
Am J Respir Crit Care Med
, vol.162
, pp. 2117-2124
-
-
Moore, P.E.1
Laporte, J.D.2
Abraham, J.H.3
Schwartzman, I.N.4
Yandava, C.N.5
Silverman, E.S.6
-
9
-
-
0031466866
-
Association between genetic polymorphisms of the beta 2-adrenoceptor and response to albuterol in children with and without a history of wheezing
-
Martinez FD, Graves PE, Baldini M, Solomon S, Erickson R. Association between genetic polymorphisms of the beta 2-adrenoceptor and response to albuterol in children with and without a history of wheezing. J Clin Invest 1997; 100: 3184-8.
-
(1997)
J Clin Invest
, vol.100
, pp. 3184-3188
-
-
Martinez, F.D.1
Graves, P.E.2
Baldini, M.3
Solomon, S.4
Erickson, R.5
-
10
-
-
0033915078
-
The effect of polymorphisms of the beta (2)-adrenergic receptor on the response to regular use of albuterol in asthma
-
Israel E, Drazen JM, Liggett SB, Boushey HA, Cherniack RM, Chinchilli VM, et al. The effect of polymorphisms of the beta (2)-adrenergic receptor on the response to regular use of albuterol in asthma. Am J Respir Crit Care Med 2000; 162: 75-80.
-
(2000)
Am J Respir Crit Care Med
, vol.162
, pp. 75-80
-
-
Israel, E.1
Drazen, J.M.2
Liggett, S.B.3
Boushey, H.A.4
Cherniack, R.M.5
Chinchilli, V.M.6
-
11
-
-
6944232728
-
National Heart, Lung, and Blood Institute's Asthma Clinical Research Network. Use of regularly scheduled albuterol treatment in asthma: Genotype-stratified, randomised, placebo-controlled cross-over trial
-
Israel E, Chinchilli VM, Ford JG, Boushey HA, Cherniack R, Craig TJ, et al. National Heart, Lung, and Blood Institute's Asthma Clinical Research Network. Use of regularly scheduled albuterol treatment in asthma: genotype-stratified, randomised, placebo-controlled cross-over trial. Lancet 2004; 364: 1505-12.
-
(2004)
Lancet
, vol.364
, pp. 1505-1512
-
-
Israel, E.1
Chinchilli, V.M.2
Ford, J.G.3
Boushey, H.A.4
Cherniack, R.5
Craig, T.J.6
-
12
-
-
33645110637
-
National Heart, Lung, and Blood Institute's Asthma Clinical Research Network. Beta-Adrenergic receptor polymorphisms and response to salmeterol
-
Wechsler ME, Lehman E, Lazarus SC, Lemanske RF Jr, Boushey HA, Deykin A, et al. National Heart, Lung, and Blood Institute's Asthma Clinical Research Network. Beta-Adrenergic receptor polymorphisms and response to salmeterol. Am J Respir Crit Care Med 2006; 173: 519-26.
-
(2006)
Am J Respir Crit Care Med
, vol.173
, pp. 519-526
-
-
Wechsler, M.E.1
Lehman, E.2
Lazarus, S.C.3
Lemanske Jr, R.F.4
Boushey, H.A.5
Deykin, A.6
-
13
-
-
48349102008
-
-
Japanese source
-
Japanese source
-
-
-
-
14
-
-
33745675688
-
Molecular-based haplotype analysis of the beta2-adrenergic receptor gene (ADRB2) in Japanese asthmatic and non-asthmatic subjects
-
Munakata M, Harada Y, Ishida T, Saito J, Nagabukuro A, Matsushita H, et al. Molecular-based haplotype analysis of the beta2-adrenergic receptor gene (ADRB2) in Japanese asthmatic and non-asthmatic subjects. Allergol Int 2006; 55: 191-8.
-
(2006)
Allergol Int
, vol.55
, pp. 191-198
-
-
Munakata, M.1
Harada, Y.2
Ishida, T.3
Saito, J.4
Nagabukuro, A.5
Matsushita, H.6
-
15
-
-
33747622353
-
Association between nonspecific airway hyperresponsiveness and Arg16Gly beta2-adrenergic receptor gene polymorphism in asymptomatic healthy Japanese subjects
-
Fukui Y, Hizawa N, Takahashi D, Maeda Y, Jinushi E, Konno S, et al. Association between nonspecific airway hyperresponsiveness and Arg16Gly beta2-adrenergic receptor gene polymorphism in asymptomatic healthy Japanese subjects. Chest 2006; 130: 449-54.
-
(2006)
Chest
, vol.130
, pp. 449-454
-
-
Fukui, Y.1
Hizawa, N.2
Takahashi, D.3
Maeda, Y.4
Jinushi, E.5
Konno, S.6
-
16
-
-
0030860288
-
Association between beta 2-adrenoceptor polymorphism and susceptibility to bronchodilator desensitization in moderately severe stable asthmatics
-
Tan S, Hall IP, Dewar J, Dow E, Lipworth B. Association between beta 2-adrenoceptor polymorphism and susceptibility to bronchodilator desensitization in moderately severe stable asthmatics. Lancet 1997; 350: 995-9.
-
(1997)
Lancet
, vol.350
, pp. 995-999
-
-
Tan, S.1
Hall, I.P.2
Dewar, J.3
Dow, E.4
Lipworth, B.5
-
17
-
-
0037075320
-
2-adrenergic receptor
-
2-adrenergic receptor. N Engl J Med 2002; 346: 536-8.
-
(2002)
N Engl J Med
, vol.346
, pp. 536-538
-
-
Liggett, S.B.1
-
19
-
-
0026595475
-
The use of beta-agonists and the risk of death and near death from asthma
-
Spitzer WO, Suissa S, Ernst P, Horwitz RI, Habbick B, Cockcroft D, et al. The use of beta-agonists and the risk of death and near death from asthma. N Engl J Med 1992 20; 326: 501-6.
-
(1992)
N Engl J Med
, vol.20
, Issue.326
, pp. 501-506
-
-
Spitzer, W.O.1
Suissa, S.2
Ernst, P.3
Horwitz, R.I.4
Habbick, B.5
Cockcroft, D.6
-
20
-
-
33745306721
-
Meta-analysis: Effect of long-acting beta-agonists on severe asthma exacerbations and asthma-related deaths
-
Salpeter SR, Buckley NS, Ormiston TM, Salpeter EE. Meta-analysis: effect of long-acting beta-agonists on severe asthma exacerbations and asthma-related deaths. Ann Intern Med. 2006 20; 144: 904-12.
-
(2006)
Ann Intern Med
, vol.20
, Issue.144
, pp. 904-912
-
-
Salpeter, S.R.1
Buckley, N.S.2
Ormiston, T.M.3
Salpeter, E.E.4
-
21
-
-
0029043604
-
Bronchodilator subsensitivity to salbutamol after twice daily salmeterol in asthmatic patients
-
Grove A, Lipworth BJ. Bronchodilator subsensitivity to salbutamol after twice daily salmeterol in asthmatic patients. Lancet 1995; 346: 201-6.
-
(1995)
Lancet
, vol.346
, pp. 201-206
-
-
Grove, A.1
Lipworth, B.J.2
-
22
-
-
0025223381
-
Regular inhaled beta-agonist treatment in bronchial asthma
-
Sears MR, Taylor DR, Print CG, Lake DC, Li QQ, Flannery EM, et al. Regular inhaled beta-agonist treatment in bronchial asthma. Lancet 1990; 336: 1391-6.
-
(1990)
Lancet
, vol.336
, pp. 1391-1396
-
-
Sears, M.R.1
Taylor, D.R.2
Print, C.G.3
Lake, D.C.4
Li, Q.Q.5
Flannery, E.M.6
-
23
-
-
2442552858
-
Meta-analysis: Respiratory tolerance to regular beta 2-agonist use in patients with asthma
-
Salpeter SR, Ormiston TM, Salpeter EE. Meta-analysis: respiratory tolerance to regular beta 2-agonist use in patients with asthma. Ann Intern Med 2004 18; 140: 802-13.
-
(2004)
Ann Intern Med
, vol.18
, Issue.140
, pp. 802-813
-
-
Salpeter, S.R.1
Ormiston, T.M.2
Salpeter, E.E.3
-
24
-
-
0030612187
-
Beta2-agonists prevent Th1 development by selective inhibition of interleukin 12
-
Panina-Bordignon P, Mazzeo D, Lucia PD, D'Ambrosio D, Lang R, Fabbri L, et al. Beta2-agonists prevent Th1 development by selective inhibition of interleukin 12. J Clin Invest 1997; 100: 1513-9.
-
(1997)
J Clin Invest
, vol.100
, pp. 1513-1519
-
-
Panina-Bordignon, P.1
Mazzeo, D.2
Lucia, P.D.3
D'Ambrosio, D.4
Lang, R.5
Fabbri, L.6
-
25
-
-
4544261946
-
-
Heijink IH, van den, Berge M, Vellenga E, de Monchy JG, Postma DS, Kauffman HF. Altered beta2-adrenergic regulation of T cell activity after allergen challenge in asthma Clin Exp Allergy 2004; 34: 1356-63.
-
Heijink IH, van den, Berge M, Vellenga E, de Monchy JG, Postma DS, Kauffman HF. Altered beta2-adrenergic regulation of T cell activity after allergen challenge in asthma Clin Exp Allergy 2004; 34: 1356-63.
-
-
-
-
26
-
-
0141924198
-
Desensitization of beta 2-adrenoceptor-mediated responses by short-acting beta 2-adrenoceptor agonists in human lung mast cells
-
Chong LK, Suvarna K, Chess-Williams R, Peachell PT. Desensitization of beta 2-adrenoceptor-mediated responses by short-acting beta 2-adrenoceptor agonists in human lung mast cells. Br J Pharmacol 2003; 138: 512-20.
-
(2003)
Br J Pharmacol
, vol.138
, pp. 512-520
-
-
Chong, L.K.1
Suvarna, K.2
Chess-Williams, R.3
Peachell, P.T.4
-
27
-
-
0035156580
-
Enhancement of goblet cell hyperplasia and airway hyperresponsiveness by salbutamol in a rat model of atopic asthma
-
Kamachi A, Munakata M, Nasuhara Y, Nishimura M, Ohtsuka Y, Amishima M, et al. Enhancement of goblet cell hyperplasia and airway hyperresponsiveness by salbutamol in a rat model of atopic asthma. Thorax 2001; 56: 19-24.
-
(2001)
Thorax
, vol.56
, pp. 19-24
-
-
Kamachi, A.1
Munakata, M.2
Nasuhara, Y.3
Nishimura, M.4
Ohtsuka, Y.5
Amishima, M.6
-
28
-
-
0347319054
-
The arginine-16 beta 2-adrenoceptor polymorphism predisposes to bronchoprotective subsensitivity in patients treated with formoterol and salmeterol
-
Lee DK, Currie GP, Hall IP, Lima JJ, Lipworth BJ. The arginine-16 beta 2-adrenoceptor polymorphism predisposes to bronchoprotective subsensitivity in patients treated with formoterol and salmeterol. Br J Clin Pharmacol 2004; 57: 68-75.
-
(2004)
Br J Clin Pharmacol
, vol.57
, pp. 68-75
-
-
Lee, D.K.1
Currie, G.P.2
Hall, I.P.3
Lima, J.J.4
Lipworth, B.J.5
-
29
-
-
0033841788
-
Asthma exacerbations during long term beta agonist use: Influence of beta (2) adrenoceptor polymorphism
-
Taylor DR, Drazen JM, Herbison GP, Yandava CN, Hancox RJ, Town GI. Asthma exacerbations during long term beta agonist use: influence of beta (2) adrenoceptor polymorphism. Thorax 2000; 55: 762-7.
-
(2000)
Thorax
, vol.55
, pp. 762-767
-
-
Taylor, D.R.1
Drazen, J.M.2
Herbison, G.P.3
Yandava, C.N.4
Hancox, R.J.5
Town, G.I.6
-
30
-
-
33144476873
-
SMART Study Group. The Salmeterol Multicenter Asthma Research Trial: A comparison of usual pharmacotherapy for asthma or usual pharmacotherapy plus salmeterol
-
Nelson HS, Weiss ST, Bleecker ER, Yancey SW, Dorinsky PM. SMART Study Group. The Salmeterol Multicenter Asthma Research Trial: a comparison of usual pharmacotherapy for asthma or usual pharmacotherapy plus salmeterol. Chest 2006; 129: 15-26.
-
(2006)
Chest
, vol.129
, pp. 15-26
-
-
Nelson, H.S.1
Weiss, S.T.2
Bleecker, E.R.3
Yancey, S.W.4
Dorinsky, P.M.5
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