Sweet preference, Obesity and genetic polymorphism of Leptin and the Leptin receptor

Hypertension Research

Volumn 31, Issue 6, 2008, Pages 1055-1056

  Hisatome, Ichiro ^a  

^a TOTTORI UNIVERSITY   (Japan)

Author keywords

Genetic polymorphism; Leptin; Obesity; Sweet preference

Indexed keywords

ADENINE; GUANINE; LEPTIN; LEPTIN RECEPTOR; POTASSIUM; RECOMBINANT LEPTIN;

CARDIOVASCULAR DISEASE; ENERGY EXPENDITURE; FATTY ACID OXIDATION; FOOD INTAKE; GENE OVEREXPRESSION; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENOTYPE; GLUCONEOGENESIS; HUMAN; HYPERTENSION; HYPOTHALAMUS HYPOPHYSIS SYSTEM; INSULIN RELEASE; INSULIN RESISTANCE; LIFESTYLE; NONHUMAN; NOTE; OBESITY; POTASSIUM CONDUCTANCE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN SECRETION; RECEPTOR BINDING; RISK FACTOR; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; SWEETNESS; TASTE PREFERENCE; TISSUE DISTRIBUTION; WEIGHT REDUCTION;

FOOD PREFERENCES; HUMANS; LEPTIN; OBESITY; POLYMORPHISM, GENETIC; RECEPTORS, LEPTIN; TASTE;

EID: 48349092520     PISSN: 09169636     EISSN: 13484214     Source Type: Journal    
DOI: 10.1291/hypres.31.1055     Document Type: Note

References (6)

1. Abate N: Obesity and cardiovascular disease: pathogenic role of the metabolic syndrome and therapeutic implications. J Diabetes Complications 2000; 14: 154-174.
2. Zhang YY, Proenca R, Maffei M, Barone, M, Leopold L, Friedman JM: Positional cloning of the mouse obese gene and its human homolog. Nature 1994; 372: 425-432.
3. Chung WK, Power-Kehoe, Chua M, et al: Exonic and intronic sequence variation in the human leptin receptor gene. Diabetes 1997; 46: 1509-1511.
4. Kawai Y, Sugimoto K, Nakashima K, Miura H, Ninomiya Y: Leptin as a modulator of sweet taste sensitivities in mice. Proc Natl Acad Sci USA 2000; 97: 11044-11049.
5. Mizuta E, Kokubo Y, Yamanaka I, et al: Leptin gene and leptin receptor gene polymorphism are associated with sweet preference and obesity. Hypertens Res 2008; 31: 1069-1077.
6. Shigemura N, Ohta R, Kusakabe Y, et al: Leptin modulates behavioral response to sweet substances by influencing peripheral taste structure. Endocrinology 2004; 145: 839-847.