A note on tree gatekeeping procedures in clinical trials

Statistics in Medicine

Volumn 27, Issue 17, 2008, Pages 3446-3451

  Dmitrienko, Alex ^a   Tamhane, Ajit C ^b   Liu, Lingyun ^b   Wiens, Brian L ^c  

^a ELI LILLY AND COMPANY   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c GILEAD SCIENCES   (United States)

Author keywords

Clinical trials; Multiple endpoints; Multiple tests

Indexed keywords

ALGORITHM; ARTICLE; BIOSTATISTICS; BONFERRONI TREE GATEKEEPING PROCEDURE; CLINICAL RESEARCH; HYPOTHESIS; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE;

ALGORITHMS; CLINICAL TRIALS AS TOPIC; DATA INTERPRETATION, STATISTICAL; DECISION TREES; ENDPOINT DETERMINATION; HUMANS; RESEARCH DESIGN;

EID: 48249151795     PISSN: 02776715     EISSN: 10970258     Source Type: Journal    
DOI: 10.1002/sim.3307     Document Type: Article

References (2)

1. Dmitrienko A, Wiens BL, Tamhane AC, Wang X. Tree-structured gatekeeping tests in clinical trials with hierarchically ordered multiple objectives. Statistics in Medicine 2007; 26:2465-2478.
2. Hommel G, Bretz F, Maurer W. Powerful short-cuts for multiple testing procedures with special reference to gatekeeping strategies. Statistics in Medicine 2007; 26:4063-4073.