Tree-structured gatekeeping tests in clinical trials with hierarchically ordered multiple objectives

Statistics in Medicine

Volumn 26, Issue 12, 2007, Pages 2465-2478

  Dmitrienko, Alex ^a   Wiens, Brian L ^b   Tamhane, Ajit C ^c   Wang, Xin ^d  

^a ELI LILLY AND COMPANY   (United States)

^b Myogen Inc   (United States)

^c NORTHWESTERN UNIVERSITY   (United States)

^d SANOFI   (France)

Author keywords

Clinical trials; Dose finding; Muliple tests; Multiple endpoints

Indexed keywords

CHOLESTEROL;

ALGORITHM; ARTICLE; CHOLESTEROL BLOOD LEVEL; CLINICAL TRIAL; DECISION TREE; DOSE CALCULATION; GLUCOSE BLOOD LEVEL; HEMOGLOBIN BLOOD LEVEL; HUMAN; HYPERTENSION; HYPOTHESIS; NON INSULIN DEPENDENT DIABETES MELLITUS; NULL HYPOTHESIS; STATISTICAL ANALYSIS;

ANTIHYPERTENSIVE AGENTS; BLOOD GLUCOSE; BLOOD PRESSURE; BLOOD PRESSURE MONITORING, AMBULATORY; CHOLESTEROL, HDL; CLINICAL TRIALS; DATA INTERPRETATION, STATISTICAL; DECISION TREES; DIABETES MELLITUS, TYPE 2; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; HYPERTENSION; HYPOGLYCEMIC AGENTS; RESEARCH DESIGN;

EID: 34248999506     PISSN: 02776715     EISSN: 10970258     Source Type: Journal    
DOI: 10.1002/sim.2716     Document Type: Article

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