Enzymatic Inhibitory Activity and Trypanocidal Effects of Extracts and Compounds from Siphoneugena densiflora O. Berg and Vitex polygama Cham

Zeitschrift fur Naturforschung - Section C Journal of Biosciences

Volumn 63, Issue 5-6, 2008, Pages 371-382

  Gallo, Margareth B C ^a   Marques, Anna Sylvia F ^a   Vieira, Paulo C ^a   da Silva, Maria Fatima Das G F ^a   Fernandes, Joao B ^a   Silva, Marcio ^b   Guido, Rafael V ^b   Oliva, Glaucius ^b   Thiemann, Otévio H ^b   Albuquerque, Sérgio ^b   Fairlamb, Alan H ^c  

^a FEDERAL UNIVERSITY OF SÃO CARLOS   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Leishmania; Myrtaceae; Trypanosoma

Indexed keywords

ANTITRYPANOSOMAL AGENT; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; PARASITE ANTIGEN; PLANT EXTRACT; SOLVENT;

ANIMAL; ARTICLE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; EUGENIA; ISOLATION AND PURIFICATION; TRYPANOSOMA CRUZI; VITEX;

ANIMALS; ANTIGENS, PROTOZOAN; EUGENIA; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASES; INDICATORS AND REAGENTS; PLANT EXTRACTS; SOLVENTS; TRYPANOCIDAL AGENTS; TRYPANOSOMA CRUZI; VITEX;

LAMIACEAE; LEISHMANIA TARENTOLAE; MAGNOLIOPHYTA; MYRTACEAE; SIPHONEUGENA DENSIFLORA; TRYPANOSOMA; TRYPANOSOMA BRUCEI; TRYPANOSOMA CRUZI; VERBENACEAE; VITEX; VITEX POLYGAMA;

EID: 48249122753     PISSN: 09395075     EISSN: None     Source Type: Journal    
DOI: 10.1515/znc-2008-5-611     Document Type: Article

References (38)

1. Bakker B. M., Westerhoff H. V., Opperdoes F. R., and Michels P. A. M. (2000), Metabolic control analysis of glycolysis in trypanosomes as an approach to improve selectivity and effectiveness of drugs. Mol. Biochem. Parasitol. 106, 1-10.
2. Besson E., Dellamonica G., Chopin J., Markham K. R., Kim M., Koh H., and Fukami H. (1985), C-Glycosyl-flavones from Oryza sativa. Phytochemistry 24, 1061-1064.
3. Brieskorn V. C. H. and Riedel W. (1977), Flavonoide aus Coleus amboinicus. Planta Med. 31, 308-310.
4. Chiappini I., Fardella G., Menghini A., and Rossi C. (1982), Flavonoids from Dittrichia viscosa. Planta Med. 44, 159-161.
5. Davidson B. S., Eisner T., Witz B., and Meinwald J. (1989), Defense mechanisms of arthropods No. 87. Defensive secretion of the carabid beetle Pasimachus subsulcatus. J. Chem. Ecol. 15, 1689-1697.
6. Dayrit F. M., Lapid M. R. G., Cagampang J. V., and La-gurin L. G. (1987), Phytochemical studies on the leaves of Vitex negundo L. (“Lagundi”). I. Investigation of the bronchial relaxing constituents. Philipp. J. Sci. 116, 403-410.
7. Fairlamb A. H., Blackburn P., Ulrich P., Chait B. T., and Cerami A. (1995), Trypanothione: a novel bis (gluta-thionyl) spermidine cofactor for glutathione reductase in trypanosomatids. Ann. Rev. Microbiol. 46, 695-729.
8. Gallo M. B. C., Rocha W. C., Cunha U. S., Diogo F. A., Silva F. C., Vieira P. C., Vendramim J. D., Fernandes J. B., Silva M. F. G. F., and Batista-Pereira L. G. (2006a), Bioactivity of extracts and isolated compounds from Vitex polygama (Verbenaceae) and Si-phoneugena densiflora (Myrtaceae) against Spodo-ptera frugiperda (Lepidoptera: Noctuidae). Pest. Manag. Sci. 62, 1072-1081.
9. Gallo M. B. C., Silva F. C., Vieira P. C., Fernandes J. B., and Silva M. F. G. F. (2006b), New natural products from Siphoneugena densiflora Berg (Myrtaceae) and their chemotaxonomic significance. J. Braz. Chem. Soc. 17, 279-288.
10. Gallo M. B. C., Beltrame F. L., Vieira P. C., Cass Q. B., Fernandes J. B., and Silva M. F. G. F. (2006c), Quantitative determination of 20-hydroxyecdysone in methanolic extract of twigs from Vitex polygama Cham. J. Chromatogr. B 832, 36-40.
11. Gallo M. B. C., Vieira P. C., Fernandes J. B., Silva M. F. G. F., and Salimena-Pires F. R. (2008), Compounds from Vitex polygama active against kidney diseases. J. Ethnopharmacol. 115, 320-322.
12. Grael C. F. F., Albuquerque S., and Lopes J. L. C. (2005), Chemical constituents of Lychnophora pohlii and trypanocidal activity of crude extracts and of isolated compounds. Fitoterapia 76, 73-82.
13. Hamilton C. J., Saravanamuthu A., Eggleston I. M., and Fairlamb A. H. (2003), Ellman's-reagent-mediated regeneration of trypanothione in situ: substrate-economical microplate and time-dependent inhibition assays for trypanothione reductase. Biochem. J. 369, 529-537.
14. Hirumi H. and Hirumi K. (1989), Continuous cultivation of Trypanosoma brucei bloodstream forms in a medium containing a low concentration of serum protein without feeder cell layers. J. Parasitol. 75, 985-989.
15. Kulkarni A. D., Modak H. M., Jadhav S. J., and Khan R. (1989), Preparation and commercial significance of 5-hydroxymethyl-2-furancarboxaldehyde: a review. J. Sci. Ind. Res. 47, 335-339.
16. Leitao S. G. and Delle Monache F. (1998), 2-O-Caffeo-ylorientin from Vitex polygama. Phytochemistry 49, 2167-2169.
17. Leitao S. G., Melo F. P. G., Delle Monache F., Goncalves J. L. S., and Wigg M. D. (1997), Inhibitory activity of Vitex polygama extracts against Herpes simplex type-1. Bull. Chim. Farmac. 136, 121.
18. Lio M., Moriyama A., Matsumoto Y., Takaki N., and Fukumoto M. (1985), Inhibition of xanthine oxidase by flavonoids by folate compounds and by ametho-pterin. J. Biol. Chem. 259, 12-15.
19. Mahato S. B. and Kundu A. P. (1994), 13C NMR spectra of pentacyclic triterpenoids-a compilation and some salient features. Phytochemistry 37, 1517-1575.
20. Mensor L. L., Menezes F. S., Leitao G. G., Reis A. S., Santos T. C., Coube C. S., and Leitao S. G. (2001), Screening of Brazilian plant extracts for antioxidant activity by the use of DPPH free radical method. Phy-tother. Res. 15, 127-130.
21. Musick W. D. (1981), Structural features of the phos-phoribosyltransferases and their relationship to the human deficiency disorders of purine and pyrimidine metabolism. CRC Crit. Rev. Biochem. 11, 1-34.
22. Opperdoes F. R. and Michels P. A. M. (2001), Enzymes of carbohydrate metabolism as potential drug targets. Int. J. Parasitol. 31, 482-490.
23. Pettit G. R., Cragg G. M., and Singh S. B. (1987), Constituents of Combretum caffrum. J. Nat. Prod. 50, 386-391.
24. Programa Biota FAPESP. (2007), List of species in extinction in Sao Paulo State, Brazil, http: //www. biota. org. br/info/wap/lista1qrs. html
25. Räz B., Iten M., Grether-Bühler Y., Kaminsky R., and Brun R. (1997), The Alamar Blue® assay to determine drug sensitivity of African trypanosomes (T brucei rhodesiense and T. brucei gambiense) in vitro. Acta Tropica 68, 139-147.
26. Rodrigues L. A. (2001), Estudo Floristico e Estrutural da Comunidade Arbustiva e Arborea de uma Floresta em Luminarias, MG, e Informacoes Etnobotanicas da Populacao Local. Master's Dissertation, Universidade Federal de Lavras, MG, Brazil, p. 190.
27. Roitman J. N. and James L. F. (1985), Chemistry of toxic range plants. Highly oxygenated flavonol methyl ethers from Gutierrezia microcephala. Phytochemistry 24, 835-848.
28. Russel K. M., Molan P. C., Wilkins A. L., and Holland P. T. (1990), Identification of some antibacterial constituents of New Zealand Manuka honey. J. Agric. Food Chem. 38, 10-13.
29. Sakushima A., Coskun M., and Maoka T. (1995), Hy-droxybenzoic acids from Boreava orientalis. Phytochemistry 40, 257-261.
30. Santos T. C., Delle Monache F., and Leitao S. G. (2001), Ecdysteroids from two Brazilian Vitex species. Fitoterapia 72, 215-220.
31. Sobral M. and Proenca C. E. B. (2006), Siphoneugena delicata (Myrtaceae), a new species from the montane Atlantic forest of southeastern Brazil. Novon 16, 530-532.
32. Southwick L., Mabry T. J., Averett J., and Powell A. M. (1972), Penduletin 4′-O-methyl ether from Perityle vaseyi. Phytochemistry 11, 2351.
33. Suksamrarn A. and Sommechai C. (1993), Ecdysteroids from Vitex pinnata. Phytochemistry 32, 303-306.
34. Suttanut K., Sripanidkulchai B., Yenjai C., and Jay M. (2007), Simultaneous identification and quantitation of 11 flavonoid constituents in Kaempferia parviflora by gas chromatography. J. Chromatogr. A 1143, 227-233.
35. Takeara R., Albuquerque S., Lopes N. P., and Lopes J. L. C. (2003), Trypanocidal activity of Lychnophora staa-vioides Mart. (Vernonieae, Asteraceae). Phytomedicine 10, 490-493.
36. Thiemann O. H., Alfonzo J. D., and Simpson L. (1998), Cloning and characterization of Leishmania tarentolae adenine phosphoribosyltransferase. Mol. Biochem. Parasitol. 95, 141-146.
37. Vieira P. C., Mafezoli J., Pupo M. T., Fernandes J. B., Silva M. F. G. F., Albuquerque S., Oliva G., and Paväo F. (2001), Strategies for the isolation and identification of trypanocidal compounds from the Rutales. Pure Appl. Chem. 73, 617-622.
38. WHO (World Health Organization) (2007), http: // www. who. int/tdr