Uptake of testing for BRCA1/2 mutations in South East Scotland

European Journal of Human Genetics

Volumn 16, Issue 8, 2008, Pages 906-912

  Holloway, Susan M ^a   Bernhard, Birgitta ^a   Campbell, Harry ^b   Lam, Wayne W K ^a  

^a WESTERN GENERAL HOSPITAL   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN;

ADULT; AGE DISTRIBUTION; ARTICLE; BREAST CANCER; CANCER FAMILY; FAMILY STUDY; FEMALE; GENE IDENTIFICATION; GENETIC COUNSELING; GENETIC SCREENING; GENETIC SUSCEPTIBILITY; HETEROZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; MALE; MUTATIONAL ANALYSIS; OVARY CANCER; PRIORITY JOURNAL; RELATIVE; RISK ASSESSMENT; SEX RATIO; SOCIAL STATUS; UNITED KINGDOM;

ADULT; BRCA1 PROTEIN; BRCA2 PROTEIN; BREAST NEOPLASMS; FAMILY; FEMALE; GENETIC COUNSELING; GENETIC PREDISPOSITION TO DISEASE; GENETIC SCREENING; GERM-LINE MUTATION; HUMANS; MALE; SCOTLAND;

EID: 48249103090     PISSN: 10184813     EISSN: 14765438     Source Type: Journal    
DOI: 10.1038/ejhg.2008.17     Document Type: Article

References (19)

1. Lerman C, Seay J, Balshem A, Audrain J: Interest in genetic testing among first-degree relatives of breast cancer patients. Am J Med Genet 1995; 57: 385-392.
2. Struewing JP, Lerman C, Kase RG, Giambarresi TR, Tucker MA: Anticipated uptake and impact of genetic testing in hereditary breast and ovarian cancer families. Cancer Epidemiol Biomarkers Prev 1995; 4: 169-173.
3. Jacobsen PB, Valdimarsdottier HB, Brown KL, Offit K: Decision-making about genetic testing among women at familial risk for breast cancer. Psychosom Med 1997; 59: 459-466.
4. Brooks L, Lennard F, Shenton A et al: BRCA1/2 predictive testing: a study of uptake in two centres. Eur J Hum Genet 2004; 12: 654-662.
5. McLoone P: Carstairs scores for Scottish postcode sectors from the 2001 Census. MRC Social and Public Health Sciences Unit. University of Glasgow: Glasgow, 2004.
6. Julian-Reynier C, Sobol H, Sévilla C, Noguès C, Bourret P, The French Cancer Genetic Network: Uptake of hereditary breast/ovarian cancer genetic testing in a French national sample of BRCA1 families. Psychooncology 2000; 9: 504-510.
7. Biesecker BB, Ishibe N, Hadley DW et al: Psychosocial factors predicting BRCA1/BRCA2 testing decisions in members of hereditary breast and ovarian cancer families. Am J Med Genet 2000; 93: 257-263.
8. Peterson SK, Watts BG, Koehly LM et al: How families communicate about HNPCC genetic testing: Findings from a qualitative study. Am J Med Genet 2003; 119C: 78-86.
9. Meijers-Heijboer EJ, Verhoog LC, Brekelmans CT et al: Presymptomatic DNA testing and prophylactic surgery in families with a BRCA1 or BRCA2 mutation. Lancet 2000; 355: 2015-2020.
10. Lerman C, Daly M, Masny A, Balshem A: Attitudes about genetic testing for breast-ovarian cancer susceptibility. J Clin Oncol 1994; 12 843-850.
11. Armstrong K, Micco E, Carney A, Stopfer J, Putt M: Racial differences in the use of BRCA1/2 testing among women with a family history of breast and ovarian cancer. JAMA 2005; 293: 1729-1736.
12. Meiser B, Butow P, Barratt A et al: Attitudes to genetic testing for breast cancer susceptibility in women at increased risk of developing hereditary breast cancer. J Med Genet 2000; 37: 472-476.
13. Gwyn K, Vernon SW, Conoley PM: Intention to pursue genetic testing for breast cancer among women due for screening mammography. Cancer Epidemiol Biomarkers Prev 2003; 12: 96-102.
14. Kash KM, Ortega-Verdejo K, Dabney MK, Holland JC, Miller DG, Osborne MP: Psychosocial aspects of cancer genetics: Women at high risk for breast and ovarian cancer. Semin Surg Oncol 2000; 18: 333-338.
15. Lerman C, Hughes C, Trock BJ et al: Genetic testing in families with hereditary nonpolyposis colon cancer. JAMA 1999; 281: 1618-1622.
16. Bottorff JL, Ratner PA, Balneaves LG et al: Women's interest in genetic testing for breast cancer risk: The influence of sociodemographics and knowledge. Cancer Epidemiol Biomarkers Prev 2002; 11: 89-95.
17. Keogh LA, Southney MC, Maskiell J et al: Uptake of offer to receive genetic information about BRCA1 and BRCA2 mutations in an Australian population-based study. Cancer Epidemiol Biomarkers Prev 2004; 13: 2258-2263.
18. Patenaude AF, Dorval M, DiGianni LS, Schneider KA, Chittenden A, Garber JE: Sharing BRCA1/2 test results with first-degree rFlatives: factors predicting who women tell. J Clin Oncol 2006; 24: 700-706.
19. Foster C, Evans DG, Eeles R et al: Non uptake of predictive genetic testing for BRCA1/2 among relatives of known carriers: attributes, cancer worry, and barriers to testing in a multicenter clinical cohort. Genet Test 2004; 8: 23-29.