Characterization of glycopeptides, aminoglycosides and macrolide resistance among Enterococcus faecalis and Enterococcus faecium isolates from hospitals in Tehran

Polish Journal of Microbiology

Volumn 57, Issue 2, 2008, Pages 173-178

  Émaneini, Mohammad ^a   Aligholi, Marzieh ^a   Aminshahi, Maneli ^b  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b Pars General Hospital Tehran   (Iran)

Author keywords

AMEs; Enterococcus faecalis; Enterococcus faecium; erm; Vancomycin resistant enterococci; VRE

Indexed keywords

AMIKACIN; AMINOGLYCOSIDE ANTIBIOTIC AGENT; AMINOGLYCOSIDE MODIFYING ENZYME; DRUG METABOLIZING ENZYME; ERYTHROMYCIN; ERYTHROMYCIN RESISTANT METHYLASE A; ERYTHROMYCIN RESISTANT METHYLASE B; ERYTHROMYCIN RESISTANT METHYLASE C; GENTAMICIN; KANAMYCIN; MACROLIDE; METHYLTRANSFERASE; NETILMICIN; POLYPEPTIDE ANTIBIOTIC AGENT; STREPTOMYCIN; TEICOPLANIN; TOBRAMYCIN; VANCOMYCIN; 6' AMINOGLYCOSIDE ACETYLTRANSFERASE 2'' AMINOGLYCOSIDE PHOSPHOTRANSFERASE; 6'-AMINOGLYCOSIDE ACETYLTRANSFERASE-2''-AMINOGLYCOSIDE PHOSPHOTRANSFERASE; ACYLTRANSFERASE; BACTERIAL PROTEIN; ERMA PROTEIN, BACTERIA; KANAMYCIN KINASE; LIGASE; PHOSPHOTRANSFERASE; VANA LIGASE, BACTERIA;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIUM ISOLATION; BROTH DILUTION; CONTROLLED STUDY; DISK DIFFUSION; ENTEROCOCCUS FAECALIS; ENTEROCOCCUS FAECIUM; HOSPITAL PATIENT; HUMAN; IRAN; MINIMUM INHIBITORY CONCENTRATION; MULTIPLEX POLYMERASE CHAIN REACTION; NONHUMAN; PHENOTYPE; VANCOMYCIN RESISTANT ENTEROCOCCUS; CROSS INFECTION; DRUG EFFECT; ENZYMOLOGY; GENETICS;

ENTEROCOCCUS FAECALIS; ENTEROCOCCUS FAECIUM;

ACETYLTRANSFERASES; BACTERIAL PROTEINS; CARBON-OXYGEN LIGASES; CROSS INFECTION; DISK DIFFUSION ANTIMICROBIAL TESTS; DRUG RESISTANCE, BACTERIAL; ENTEROCOCCUS FAECALIS; ENTEROCOCCUS FAECIUM; ERYTHROMYCIN; GENES, BACTERIAL; GENTAMICINS; HUMANS; IRAN; KANAMYCIN KINASE; METHYLTRANSFERASES; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); VANCOMYCIN; VANCOMYCIN RESISTANCE;

EID: 48249085427     PISSN: 17331331     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Cetinkaya Y., P. Falk and C.G. Mayhall. 2000. Vancomycin-Resistant Enterococci. Clin. Microbiol. Rev. 13: 680-707.
2. Chow J.W, V. Kak, I. You, S.J. Kao, J. Petrin, D.B. Clewell, S.A. Lerner, G.H. Miller and K.J. Shaw. 2001. Aminoglycoside resistance genes aph (2″)-Ib and aac(6′)-Im detected together in strains of both Escherichia coli and Enterococcus faecium. Antimicrob. Agents. Chemother. 45: 2691-2694.
3. del Campo R., C. Tenorio, C. Rubio, J. Castillo, C. Torres and R. Go'mez-Lus. 2000. Ammoglycoside-modifying enzymes in high-level streptomycin and gentamicin resistant Enterococcus spp. in Spain. Int. J. Antimicrob. Agents 15: 221-226.
4. De Leener E., A. Martel, A. Decostere and F. Haesebrouck. 2004. Distribution of the erm(B) gene, tetracycline resistance genes, and Tn1545-like transposons in macrolide- and lincosamide-resistant enterococci from pigs and humans. Microb Drug Resist. 10: 341-345.
5. Dutka-Malen S., S. Evers and P. Courvalin. 1995. Detection of glycopeptide resistance genotypes and identification to the species level of clinically relevant enterococci by PCR. J. Clin. Microbiol. 33:24-27.
6. Emaneini M., F.B. Hashemi, M. Aligholi, B. Fatholahzadeh, B. Kazemi and F. Sadeghi. 2005. Detection of vanB genotype enterococci in Iran. Int. J. Antimicrob. Agents. 26:98-9.
7. Facklam R.R, and M.D. Collins. 1989. Identification of enterococcus species isolated from human infection by a conventional test scheme. J. Clin. Microbiol. 27: 731-734.
8. Feizabadi M.M., P. Maleknejad, A. Asgharzadeh, S. Asadi, L. Shokrzadeh and S. Sayadi. 2006. Prevalence of aminoglycoside-modifying enzymes genes among isolates of Enterococcus faecalis and Enterococcus faecium in Iran. Microb. Drug. Resist. 12: 265-268.
9. Feizabadi M.M., S. Asadi, A. Aliahmadi, M. Parvin, R. Parastan, M. Shayegh and G. Etemadi. 2004. Drug resistant patterns of enterococci recovered from patients in Tehran during 2000-2003. Int. J. Antimicrob. Agents 24: 521-522.
10. Forbes B. A., D.F. Sahm and A. Weisfeld. 1998. Catalase Negative Gram Positive Cocci. Baily and Scott's Diagnostic Microbiology. 10th Ed. St. Louis, Missouri. USA; Mosby Inc; P: pp. 620-635.
11. Gordon S., J.M. Swenson, B.C. Hill, N.E. Pigott, R.R. Facklam, R.C. Cooksey, C. Thornsberry, W.R. Jarvis and F.C. Tenover. 1992. Antimicrobial susceptibility patterns of common and unusual species of enterococci causing infections in the United States. Enterococcal study group. J. Clin. Microbiol. 30: 2373-2378.
12. Kaçmaz B. and A. Aksoy. 2005. Antimicrobial resistance of enterococci in Turkey. Int. J. Antimicrob. Agents 25: 535-538.
13. Kholy A., H. Baseem, G.S. Hall, G.W. Procop and D.L. Longworth. 2003. Antimicrobial resistance in Cairo, Egypt 1999-2000: a survey of five hospitals. J. Antimicrob. Chemother. 51: 625-630.
14. Lim J.A., A.R. Kwon, S.K. Kim, Y. Chong, K. Lee, and E.C. Choi. 2002. Prevalence of resistance to macrolide, lincosamide and streptogramin antibiotics in Gram-positive cocci isolated in a Korean hospital. J. Antimicrob. Chemother. 49: 489-95.
15. Martineau F., F.J. Picard and N. Lansac. 2000. Correlation between the resistance genotype determined by Multiplex-PCR assays and the antibiotic susceptibility patterns of Staphylococcus aureus and Staphylococcus epidermidis. Antimicrob. Agents. Chemother. 44: 231-238.
16. National Committee for Clinical Laboratory Standards. 2004. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. Approved Standard M7-A4. NCCLS, Wayne, PA, USA.
17. Portillo A., F. Ruiz-Larrea, M. Zarazaga, A. Alonso, J.L. Martinez and C. Torres. 2000. Macrolide resistance genes in Enterococcus spp. Antimicrob. Agents. Chemother. 44: 967-971.
18. Reyes J., M. Hidalgo, L. Díaz, S. Rincón, J. Moreno, N. Vanegas, E. Castańeda and C.A. Arias. 2007. Characterization of macrolide resistance in Gram-positive cocci from Colombian hospitals: a countrywide surveillance. Int. J. Infect. Dis. 11: 329-336.
19. Schmitz F.J., R. Sadurski, A. Kray, M. Boos, R. Geisel, K. Köhrer, K. Köhrer, J. Verhoef and A.C. Fluit. 2000. Prevalence of macrolide-resistance genes in Staphylococcus aureus and Enterococcus faecium isolates from 24 European university hospitals. J. Antimicrob. Chemother. 45: 891-894
20. Shaw K.J., P.N. Rather, R.S. Hare and G.H. Miller. 1993. Molecular genetics of aminoglycoside resistance genes and familial relationships of aminoglycoside-modifying enzymes. Microbiol. Rev. 57: 138-163.
21. Strommenger B., C. Kettlitz, G. Werner and W. Witte. 2003. Multiplex PCR assay for simultaneous detection of nine clinically relevant antibiotic resistance genes in Staphylococcus aureus. J. Clin. Microbiol. 41: 4089-4094.
22. Takeuchi K., H. Tomita, S. Fujimoto, M. Kudo, H. Kuwano and Y. Ike. 2005. Drug resistance of Enterococcus faecium clinical isolates and the conjugative transfer of gentamicin and erythromycin resistance traits. FEMS. Microbiol. Lett. 243:347-54.
23. Udo E.E., N. Al-Sweih, and T.D. Chugh. 2002. Antibiotic resistance of Enterococci isolated at a teaching hospital in Kuwait. Diagn. Microbiol. Infect. Dis. 43: 233-238.
24. Udo E.E., N. Al-Sweih, P. John, L.E. Jacob and S. Mohanakrishnan. 2004. Characterization of high-level aminoglycoside-resistant enterococci in Kuwait Hospitals. Microb. Drug. Resist. 10: 139-145.
25. Vakulenko S.B., S.M. Donabedian, A.M. Voskresenskiy, M.J. Zervos, S.A. Lerner and J.W. Chow. 2003. Multiplex PCR for detection of aminoglycoside resistance genes in enterococci. Antimicrob. Agents. Chemother. 47: 1423-1426.
26. Witte W., R. Wirth and I. Mare. 1999. Enterococci. Chemotherapy 45: 135-145.
27. Zarrilli R., M.F. Tripodi, A. Di Popolo, R. Fortunato, M. Bagattini, M. Crispino, A. Florio, M. Triassi and R. Utili. 2005. Molecular epidemiology of high-level aminoglycoside-resistant enterococci isolated from patients in a university hospital in southern Italy. J. Antimicrob. Chemother. 56: 827-835.
28. Zouain M.G. and G.F. Araj. 2001. Antimicrobial resistance of Enterococci in Lebanon. Int. J. Antimicrob. Agents 17: 209-213.