Modulation of gel formation and drug-release characteristics of lidocaine-loaded poly(vinyl alcohol)-tetraborate hydrogel systems using scavenger polyol sugars

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 69, Issue 3, 2008, Pages 1135-1146

  Loughlin, Ryan G ^a   Tunney, Michael M ^a   Donnelly, Ryan F ^a   Murphy, Diarmaid J ^a   Jenkins, Mark ^b   McCarron, Paul A ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^b ANTRIM AREA HOSPITAL   (United Kingdom)

Author keywords

Borate; Hydrogel; Lidocaine hydrochloride; Mannitol; Poly(vinyl alcohol); Polyol; Topical delivery

Indexed keywords

LIDOCAINE; MANNITOL; POLYOL; POLYVINYL ALCOHOL; POLYVINYL ALCOHOL TETRABORATE; UNCLASSIFIED DRUG;

ARTICLE; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; GEL; HYDROGEL; PH;

ANESTHETICS, LOCAL; BORATES; CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; HARDNESS TESTS; HYDROGELS; HYDROGEN-ION CONCENTRATION; LIDOCAINE; MANNITOL; POLYMERS; POLYVINYL ALCOHOL; TEMPERATURE; VISCOSITY;

EID: 48149112133     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2008.01.033     Document Type: Article

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