Investigation on insulin tyrosine modification mediated by peroxynitrite

2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007

Volumn , Issue , 2007, Pages 1813-1816

  Wang, Yunhai ^a   Luo, Yunjing ^a   Zhong, Rugang ^a  

^a BEIJING UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ANIMAL CELL CULTURE; BIOMEDICAL ENGINEERING; GLUCOSE; INSULIN; NITRATION; NITRIC OXIDE; OXYGEN; SUGAR (SUCROSE);

BIOLOGICAL ACTIVITIES; CARDIOVASCULAR COMPLICATIONS; HPLC-MS; HUMAN BLOODS; NITROTYROSINE; PATHOLOGICAL PROCESSES; PEROXYNITRITE; RECEPTOR BINDINGS; SPECTRAL CHANGES; SUPEROXIDE; TYROSINE RESIDUES;

HORMONES;

EID: 48149098740     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/ICCME.2007.4382060     Document Type: Conference Paper

References (10)

1. M. R. Reynolds, R. W. Berry, and L. I. Binder, "Site-Specific nitration and oxidative dityrosine bridging of the T protein by peroxynitrite: implications for Alzheimer's Disease," Biochemistry, vol. 44, pp. 1690-1700, May 2005.
2. A. ceriello, F. Mercuri, L. Quagliaro, R. Assaloni, E. Motz, et al. "Detection of nitrotyrosine in the diabetic plssma: evidence of oxidative stress," Diabetologia, vol. 44, pp. 834-838, July 2001.
3. L.B. Esberg and J. Ren, "Role of nitric oxide, tetrahydrobiopterin and peroxynitrite in glucose toxicity-associated contractile dysfunction in ventricular myocytes," Diabetologia, vol. 46, pp. 1419-1427, October 2003.
4. Q. Chi, T. L. Wang, and K. X. Huang "Effect of insulin nitration by peroxynitrite on its biological activity," Biochem. Bioph Res. Co. vol. 330, pp. 791-796, March 2005.
5. F. H. Carpenter, R. W. Boesel, and D. D. Sakai, "[Tetrakis(3 -Nitrotyrosine)]Insulin," Biochemistry, vol.19, pp. 5926-5931,April 1980.
6. R. M. Uppu and W. A. Pryor, "Synthesis of peroxynitrite in a two-phase system using isoamyl nitrite and hydrogen peroxide," Anal.Biochem., vol. 236, pp. 242-249, May 1996.
7. J. S. Beckman, H. Ischiropoulos, L. Zhu, M.Vanderwoerd, C. Smith, et al. "Kinetics of superoxide dismutase-datalyzed and iron-catalyze d nitration of phenolics by peroxynitrite," Arch. Biochem. Biophys., vol 298, pp. 438-445, November 1992.
8. A. M. Cassina, R. Hodara, J. M. Souza, L. Thomson, L. Castro, et al. "Cytochrome c Nitration by Peroxynitrite," J. Bio. Chem., vol 275, pp. 21409-21415, July 2000.
9. L. A. MacMillan-Crow, J. P. Crow, and J. A. Thompson "Peroxynitrite- mediated inactivation of manganese superoxide dismutase involves nitration and oxidation of critical tyrosine residues," Biochemistry vol. 37, pp. 1613-1622, January 1998.
10. S. S. Lehrer and G. D. Fasman, "Ultraviolet irradiation effects in poly-L-tyrosine and model compounds. Identification of bityrosine as a photoproduct," Biochemistry, vol. 6, pp. 757-767, March 1967.