Presumptive specific clinical diagnosis of genital ulcer disease (GUD) in a primary health care setting in Nairobi

International Journal of STD and AIDS

Volumn 7, Issue 3, 1996, Pages 201-205

  Ndinya Achola, J O ^a   Kihara, A N ^a   Fisher, L D ^b   Krone, M R ^b   Plummer, F A ^c   Ronald, A ^c   Holmes, K K ^b  

^a UNIVERSITY OF NAIROBI   (Kenya)

^b UNIVERSITY OF WASHINGTON   (United States)

^c UNIVERSITY OF MANITOBA   (Canada)

Author keywords

Chancroid; Genital ulcer; Primary care; Syndromic diagnosis; Syphilis

Indexed keywords

ANTIINFECTIVE AGENT; BENZATHINE PENICILLIN; CEFTRIAXONE; ERYTHROMYCIN; SULFAMETROLE; TETRACYCLINE; TRIMETHOPRIM;

ARTICLE; CONTROLLED STUDY; FEMALE; GENITAL ULCER; HUMAN; INTRAMUSCULAR DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; KENYA; MAJOR CLINICAL STUDY; MALE; ORAL DRUG ADMINISTRATION; PATIENT CARE; PRIORITY JOURNAL; SYPHILIS; ULCUS MOLLE;

AFRICA; AFRICA SOUTH OF THE SAHARA; CHANCROID; DELIVERY OF HEALTH CARE; DEVELOPING COUNTRIES; DISEASES; EASTERN AFRICA; ENGLISH SPEAKING AFRICA; EXAMINATIONS AND DIAGNOSES; HEALTH; HEALTH SERVICES; HEALTH SURVEYS; INFECTIONS; KENYA; PRIMARY HEALTH CARE; REPRODUCTIVE TRACT INFECTIONS; RESEARCH REPORT; SEXUALLY TRANSMITTED DISEASES; SIGNS AND SYMPTOMS; SYPHILIS; TREATMENT;

ANTI-BACTERIAL AGENTS; CHANCROID; DIAGNOSIS, DIFFERENTIAL; FEMALE; HAEMOPHILUS DUCREYI; HUMANS; KENYA; MALE; PRIMARY HEALTH CARE; PROSPECTIVE STUDIES; SENSITIVITY AND SPECIFICITY; TREATMENT OUTCOME; URBAN HEALTH;

EID: 0029906316     PISSN: 09564624     EISSN: None     Source Type: Journal    
DOI: 10.1258/0956462961917627     Document Type: Article

References (22)

1. Piot P, Plummer FA. Genital ulcer adenopathy syndrome. In: Sexually Transmitted Diseases. (2nd Edn) Holmes KK, Mardh PA, Sparling PF, et al. Eds. McGraw-Hill, 1990
2. Greenblatt RM, Lukehart SA, Plummer FA, et al. Genital ulceration as a risk factor for human immunodeficiency virus infection. AIDS 1988;2(1):47-50
3. Cameron DW, Simonsen JN, D'Costa LJ, et al. Female to male transmission of human immunodeficiency virus type-1: risk factors for seroconversion in men. Lancet 1989;ii:403-7
4. Telzak EE, Chiasson MA, Bevier PJ, et al. HIV-1 seroconversion in patients with and without genital ulcer disease. Ann Intern Med 1993;119:1181-986
5. Figuerra JP, Brathwaite A, Morris J, et al. Rising HIV-1 prevalence among sexually transmitted disease clinic attendees in Jamaica: traumatic sex and genital ulcers as risk factors. AIDS 1994;7:310-16
6. Chapel TA, et al. How reliable is the morphological diagnosis of penile ulcerations? Sex Transm Dis 1984;11:72
7. Fast MV, et al. The clinical diagnosis of genital ulcer disease in men in the tropics. Sex Transm Dis 1977;4:150
8. Plummer FA, D'Costa LJ, Nsanze H, et al. Clinical and microbiologic studies of genital ulcers in Kenyan women. Sex Transm Dis 1985;12:193
9. Dangor Y, Ballard R, Exposto FL, Fehler G, Miller SD, Koornhof HJ. Accuracy of clinical diagnosis of genital ulcer disease. Sex Transm Dis 1990;17:184-9
10. Plummer FA, Nsanze H, D'Costa LJ, et al. Single-dose therapy of chancroid with trimethoprim-sulfamethoxazole. N Engl J Med. 1983;309:67-71
11. Ronald A, Albritton W. Chancroid and Haemophilus ducreyi. In: Sexually Transmitted Disease (2nd Ed). Holmes KK, Mardh PA, Sparling PF, et al. eds McGraw Hill. 1990:263-71
12. Tyndall MW, Agoki E, Plummer FA, Malisa W, Ndinya-Achola JO, Ronald AR. Single dose azithromycin for the treatment of chancroid: a randomized comparison with erythromycin. Sex Transm Dis 1994;21:231-4
13. Bowmer MI, Nzanze H, D'Costa LJ, et al. Ceftriazone: effective single dose treatment for chancroid. Antimicrob Agents Chemother 1987;31:67-79
14. Tyndall M, Malisa M, Plummer FA, Ombetti J, Ndinya-Achola JO, Ronald AR. Ceftriaxone no longer predictably cures chancroid in Kenya. J Infect Dis 1993;167:469-71
15. Plourde PJ, D'Costa LJ, Agoki E, et al. A randomized, double-blind study of the efficacy of fleroxacin versus trimethoprim-sulfamethoxazole in men with culture-proven chancroid. J Infect Dis 1992;165:949-52
16. Kristensen JK. The prevalence of symptomatic sexually transmitted diseases and human immunodeficiency virus infection in outpatients in Lilongwe, Malawi. Genitourin Med 1990;66:244-6
17. Meheus A, Van Dijck Ursi JP, Ballard RC, Piot P. Etiology of genital ulceration in Swaziland. Sex Transm Dis 1983;10:33-5
18. Coovadia YM, Kharsany A, Hooson A. The microbial etiology of genital ulcers in black men in Durham, South Africa. Genitourin Med 1982;61:266-9
19. Ombette J, Kimani J, Ndinya-Achola JO, et al. An improved cultural medium for H. ducreyi. J Clin Micro (Submitted)
20. Dylewski J, Nsanze H, Maitha G, Ronald A. Laboratory diagnosis of Haemophilus ducreyi: sensitivity of culture media. Diag Microbiol Infect Dis 1986;4:241-5
21. Chui L, Albritton W, Paster B, Maclean I, Marusyk R. Development of the polymerase chain reaction for diagnosis of chancroid. J Clin Microbiol 1993;31:659-64
22. Wasserheit JN. Epidemiological synergy: interrelationships between human immunodeficiency virus infection and other sexually transmitted diseases. Sex Transm Dis 1992;19: 61-77