First evidence of polybrominated diphenyl ether (flame retardants) effects in feral barbel from the Ebro River basin (NE, Spain)

Chemosphere

Volumn 73, Issue 1, 2008, Pages 56-64

  Raldúa, Demetrio ^a   Padrós, Francesc ^b   Solé, Montserrat ^c   Eljarrat, Ethel ^d   Barceló, Damià ^d   Riva, Mari Carme ^a   Barata, Carlos ^d  

^a UNIVERSITAT POLITÈCNICA DE CATALUNYA   (Spain)

^b UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^c INSTITUT DE CIÈNCIES DEL MAR   (Spain)

^d CSIC   (Spain)

Author keywords

Barbus graellsii; Ebro river; EROD; Macrophage aggregates; PBDE; UDPGT

Indexed keywords

BIOCHEMISTRY; BIOMARKERS; BRAIN; DIGITAL SIGNAL PROCESSING; EFFLUENTS; ENZYMES; ETHERS; FISH; FLAME RETARDANTS; FLAME SPRAYING; FOOD ADDITIVES; LIVER; NEON; ORGANIC COMPOUNDS; PHOTOACOUSTIC EFFECT; POLLUTION; POLYACRYLATES; RIVER POLLUTION;

(ABIOTIC AND BIOTIC) STRESS; ANTIOXIDANT ENZYMES; BIOLOGICAL EFFECTS; BIVARIATE; CHOLINESTERASE (CHE); CU (II) METABOLISM; DIAPHORASE; EBRO BASIN; EBRO RIVER BASIN; ELSEVIER (CO); ENVIRONMENTAL FACTORS; GLUTATHIONE PEROXIDASE (GSH-PX); GLUTATHIONE-S-TRANSFERASE (GST); HISTOPATHOLOGICAL EFFECTS; IN-FIELD; INDUSTRIAL SITES; LIPOPHILIC (LP); METABOLIC ENZYMES; NEUROTOXICITY; NUMBER AND SIZE; PHASE I; POLY-BROMINATED DIPHENYL ETHERS (PBDE); POLYBROMINATED DIPHENYL ETHER (PBDE);

RIVERS;

CHOLINESTERASE; CYTOCHROME P450 1A; DIHYDROLIPOAMIDE DEHYDROGENASE; ETHOXYRESORUFIN DEETHYLASE; FLAME RETARDANT; GLUCURONOSYLTRANSFERASE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; OXIDOREDUCTASE; POLYBROMINATED DIPHENYL ETHER;

BIOACCUMULATION; CYPRINID; EFFLUENT; ENZYME ACTIVITY; MEASUREMENT METHOD; METABOLISM; OXIDATION; PBDE; PHYSIOLOGICAL RESPONSE; RIVER DISCHARGE;

ANIMAL TISSUE; ARTICLE; BARBUS GRAELLSII; FISH; KIDNEY DISEASE; LIVER DISEASE; LIVER METABOLISM; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; RIVER BASIN; SPAIN; WATER CONTAMINATION;

ANIMALS; BIOLOGICAL MARKERS; CYPRINIDAE; CYTOCHROME P-450 CYP1A1; ENVIRONMENTAL EXPOSURE; FISHES; FLAME RETARDANTS; GEOGRAPHY; HALOGENATED DIPHENYL ETHERS; INDUSTRIAL WASTE; KIDNEY; LIVER; MACROPHAGES; RIVERS; SPAIN; WATER POLLUTANTS, CHEMICAL;

ARAGON; CINCA RIVER; EBRO BASIN; EURASIA; EUROPE; HUESCA [ARAGON]; SOUTHERN EUROPE; SPAIN; VERO RIVER;

BARBUS; BARBUS GRAELLSII; PISCES;

EID: 48049111173     PISSN: 00456535     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chemosphere.2008.05.037     Document Type: Article

References (64)

1. Aebi H. Catalase. In: Bergmayer H.U. (Ed). Methods of Enzymatic Analysis (1974), Academic Press, London 671-684
2. Agius C., and Roberts R.J. Melano-macrophage centres and their role in fish pathology. J. Fish Dis. 26 (2003) 499-509
3. Asplund L., Athanasiadou M., Sjodin A., Bergman A., and Borjeson H. Organohalogen substances in muscle, egg and blood from healthy Baltic salmon (Salmo salar) and Baltic salmon that produced offspring with the M74 syndrome. Ambio 28 (1999) 67-76
4. Au D.W.T. The application of histo-cytopathological biomarkers in marine pollution monitoring: a review. Mar. Pollut. Bull. 48 (2004) 817-834
5. Barata C., Lekumberri I., Vila-Escalé M., Prat N., and Porte C. Trace metal concentration, antioxidant enzyme activities and susceptibility to oxidative stress in the tricoptera larvae Hydropsyche exocellata from the Llobregat Riven basin (NE Spain). Aquat. Toxicol. 74 (2005) 3-19
6. Benson A.M., Hunkeler M.J., and Talalay P. Increase of NAD(P)H quinine reductase by dietary antioxidants: possible role in protection against carcinogenesis and toxicity. Proc. Natl. Acad. Sci. USA 77 (1980) 5216-5220
7. Boon J., van Zanden J., Lewis W., Zegers B., Goksøyr A., and Arukwe A. The expression of CYP1A, vitellogenin and zona radiata proteins in Atlantic salmon (Salmo salar) after oral dosing with two commercial PBDE flame retardant mixtures: absence of short-term responses. Mar. Environ. Res. 54 (2002) 719-724
8. Branchi I., Capone F., Alleva E., and Costa L.G. Polybrominated diphenyl ethers: neurobehavioral effects following developmental exposure. NeuroToxicology 24 (2003) 449-462
9. Burke M.D., and Mayer R.T. Ethoxyresorufin: direct fluorimetric assay of a microsomal O-dealkylation which is preferentially inducible by 3-methylcholanthrene. Drug Metabol. Disp. 2 (1974) 583-588
10. Canton R.F., Sanderson J.T., Nijmeijer S., Bergman A., Letcher R.J., and van den Berg M. In vitro effects of brominated flame retardants and metabolites in CYP17 catalytic activity: a novel mechanism of action. Toxicol. Appl. Pharmacol. 216 (2006) 274-281
11. Carlberg I., and Mannervik B. Glutathione reductase. Meth. Enzymol. 113 (1985) 485-490
12. Chen G.S., Konstantinov A.D., Chittim B.G., Joyce E.M., Bols N.C., and Bunce N.J. Synthesis of polybrominated diphenyl ethers and their capacity to induce CYP1A by the Ah receptor mediated pathway. Environ. Sci. Technol. 35 (2001) 3749-3756
13. Clarke D.J., George S.G., and Burchell B. Multiplicity of UDP-glucuronosyltransferases in fish. Purification of UDP-glucuronosyltransferase from the liver of a marine teleost, Pleuronectes platessa. Biochem. J. 284 (1992) 417-423
14. Daidoji T., Gozu K., Iwano H., Inoue H., and Yokota H. UDP-glucuronosyltransferase isoforms catalyzing glucuronidation of hydroxy-polychlorinated biphenyls in rat. Drug Metabol. Disp. 33 (2005) 1466-1476
15. Darnerud P.O., and Sinjari T. Effects of polybrominated diphenylethers (PBDEs) and polychlorinated biphenyls (PCBs) on thyroxine and TSH blood levels in rats and mice. Organohalogen Comp. 29 (1996) 316-319
16. de Wit C.A. An overview of brominated flame retardants in the environment. Chemosphere 46 (2002) 583-624
17. Eljarrat E., De la Cal A., Raldua D., and Barcelo D. Occurrence and bioavailability of polybrominated diphenyl ethers and hexabromocyclododecane in Sediment and fish from the Cinca river, a tributary of the Ebro River (Spain). Environ. Sci. Technol. 38 (2004) 2603-2608
18. Eljarrat E., Labandeira A., Marsh G., Raldúa D., and Barceló D. Decabrominated diphenyl ether in river fish and sediment samples collected downstream an industrial park. Chemosphere 69 (2007) 1278-1286
19. Ellman G.L., Courtney K.D., Andres V.J., and Featherstone R.M. A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem. Pharmacol. 7 (1961) 88-95
20. Erikson P., Jakobsson E., and Fredriksson A. Brominated flame retardants: a novel class of developmental neurotoxicants in our environment?. Environ. Health Persp. 109 (2001) 903-908
21. Esterbauer H., Schaur R.J., and Zollner H. Chemistry and biochemistry of 4-hydroxynoneal, malonaldeyde and related aldehyeds. Free Radical Biol. Med. 11 (1991) 81-128
22. Facey D.E., Blazer V.S., Gasper M.M., and Turcotte C.L. Using fish biomarkers to monitor improvements in environmental quality. Aquat. Anim. Health. 17 (2005) 263-266
23. Fernie K.J., Shutt J.L., Mayne G., Hoffman D., Letcher R.J., Drouillard K.G., and Ritchie I.J. Exposure to polybrominated diphenyl ethers (PBDEs): changes in thyroid, vitamin A, glutathione homeostasis, and oxidative stress in American kestrels (Falco sparverius). Toxicol. Sci. 88 (2005) 375-383
24. Förlin L., and Anderson T. Storage conditions of rainbow trout liver cytochrome P450 and conjugating enzymes. Comp. Biochem. Physiol. 80 B (1985) 569-572
25. Fournie J.W., Summers J.K., Courtney L.A., Engle V.D., and Blazer V.S. Utility of splenic macrophage aggregates as an indicator of fish exposure to degraded environments. J. Aquat. Anim. Health. 13 (2001) 105-116
26. Greenwald R.A. Handbook of Methods for Oxygen Radical Research (1985), CRC Press, Boca Raton, FL
27. Habig W.H., Pabst M.J., and Jakoby W.B. Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. Biol. Chem. 249 (1974) 7130-7139
28. Hallgren S., and Darnerud P.O. Polybrominated diphenyl ethers (PBDEs), polychlorinated biphenyls (PCBs) and chlorinated paraffins (CPs) in rats - testing interactions and mechanisms for thyroid hormone effects. Toxicology 177 (2002) 227-243
29. Hallgren S., Sinjari T., Hakansson H., and Darnerud P.O. Effects of polybrominated diphenyl ethers (PBDEs) and polychlorinated biphenyls (PCBs) on thyroid hormone and vitamin A levels in rats and mice. Arch. Toxicol. 75 (2001) 200-208
30. Holm G., Norrgren L., Andersson T., and Thuren A. Effects of exposure to food contaminated with PBDE, PCN or PCB on reproduction, liver morphology and cytochrome P450 activity in the three-spined stickelback, Gasterosteus aculeatus. Aquat. Toxicol. 27 (1993) 33-50
31. Hu X.Z., Xu Y., Hu D.C., Hui Y., and Yang F.X. Apoptosis induction on human hepatoma cells Hep G2 of decabrominated diphenyl ether (PBDE-209). Toxicol. Lett. 171 (2007) 19-28
32. Ikonomou M.G., Rayne S., Fischer M., Fernandez M.P., and Cretney W. Occurrence and congener profiles of polybrominated diphenyl ethers (PBDEs) in environmental samples from coastal British Columbia, Canada. Chemosphere 46 (2002) 649-663
33. Kooponen K., Myers M.S., Ritola O., Huuskonen S.E., and Lindström-Seppä P. Histopathology of feral fish from a PCB-contaminated freshwater lake. Ambio 30 (2001) 122-126
34. Kuiper R., Murk A., Leonards P., Grinwis G., van der Berg M., and Vos J. In vivo and in vitro Ah-receptor activation by commercial and fractionated pentabromodiphenylether using zebrafish (Danio rerio). Aquat. Toxicol. 79 (2006) 366-375
35. Labandeira A., Eljarrat E., and Barceló D. Congener distribution of polybrominated diphenyl ethers in feral carp (Cyprinus carpio) from the Llobregat River, Spain. Environ. Pollut. 146 (2007) 188-195
36. Lema S., Schultz I., Scholz N., Incardona J., and Swanson P. Neural defects and cardiac arrhythmia in fish larvae following embryonic exposure to 2,2′,4,4′-tetrabomodiphenyl ether (PBDE 47). Aquat. Toxicol. 82 (2007) 296-307
37. Malmberg T., Athanasiadou M., Marsh G., Brandt I., and Bergmant A. Identification of hydroxylated polybrominated diphenyl ether metabolites in blood plasma from polybrominated diphenyl ether exposed rats. Environ. Sci. Technol. 39 (2005) 5342-5348
38. Marsh G., Athanasiadou M., Athanassiadis I., and Sandholm A. Identification of hydroxylated metabolites in 2,2′,4,4′-tetrabromodiphenyl ether exposed rats. Chemosphere 63 (2006) 690-697
39. McKinney M.A., de Guise S., Martineau D., Beland P., Arukwe A., and Letcher R.J. Biotransformation of polybrominated diphenyl ethers and polychlorinated biphenyls in beluga whale (Delphinapterus leucas) and rat mammalian model using an in vitro hepatic microsomal assay. Aquat. Toxicol. 77 (2006) 87-97
40. Muirhead E., Skillman A., Hook S., and Schultz I. Oral exposure of PBDE-47 in fish: toxicokinetics and reproductive effects in japanese medaka (Oryzias latipes) and fathead minnows (Pimephales promelas). Environ. Sci. Technol. 40 (2006) 523-528
41. Ni W., Trelease R.N., and Eising R. Two temporally synthesized charge subunits interact to form the five isoforms of cottonseed (Gossypium hirsutum) catalase. Biochemistry 269 (1990) 233-238
42. Norrgren L., Andersson T., and Björk M. Liver morphology and cytochrome P450 activity in fry of rainbow trout after microinjection of lipid-soluble xenobiotics in the yolk-sac embryos. Aquat. Toxicol. 26 (1993) 307-316
43. Norstrom R.J., Simon M., Moisey J., Wakeford B., and Weseloh D.V.C. Geographical distribution (2000) and temporal trends (1981-2000) of brominated diphenyl ethers in Great Lakes herring gull eggs. Environ. Sci. Technol. 36 (2002) 4783-4789
44. Porte C., Escartín E., García de la parra L.M., Biosca X., and Albaigés J. Assessment of coastal pollution by combined determination of chemical and biochemical markers in Mullus barbatus. Mar. Ecol. Prog. Ser. 235 (2002) 205-216
45. Prat N., and Munné A. Water use and quality and stream flow in a Mediterranean stream. Water Res. 15 (2000) 3876-3881
46. Prenda J., Clavero M., Blanco-Garrido F., Menor A., and Hermoso V. Threats to the conservation of biotic integrity in Iberian fluvial ecosystems. Limnetica 25 (2006) 377-388
47. Raldúa D., Díez S., Bayona J.M., and Barceló D. Mercury levels and liver pathology in feral fish living in the vicinity of a mercury cell chlor-alkaly factory. Chemosphere 66 (2007) 1217-1225
48. Scott G.R., and Sloman K.A. The effects of environmental pollutants on complex fish behavior: integrating behavioral and physiological indicators of toxicity. Aquat. Toxicol. 68 (2004) 369-392
49. Sellström U., Kierkegaard A., de Wit C., and Jansson B. Polybrominated diphenyl ethers and hexabromocyclododecane in sediment and fish from a Swedish river. Environ. Toxicol. Chem. 17 (1998) 1065-1072
50. Solé M., and Livingstone D.R. Components of the cytochrome P450-dependent monooxygenase system and NADPH-independent benzo[a]pyrene hydroxylase activity in a wide range of marine invertebrate species. Comp. Biochem. Physiol. 141C (2005) 20-31
51. Song S.B., Xu Y., and Zhou B.S. Effects of hexachlorobenzene on antioxidant status of liver and brain of common carp (Cyprinus carpio). Chemosphere 65 (2006) 699-706
52. Sonne C., Dietz R., Leifsson P.S., Born E.W., Letcher R.J., Kirkegaard M., Muir D.C.G., Riget F.F., and Hyldstrup L. Do organohalogen contaminants contribute to histopathology in liver from East Greenland polar bears (Ursus maritimus). Environ. Health Persp. 113 (2005) 1569-1574
53. Sonne C., Dietz R., Leifsson P.S., Born E.W., Kirkegaard M., Letcher R.J., Muir D.C.G., Riget F.F., and Hyldstrup L. Are organohalogen contaminants a cofactor in the development of renal lesions in east Greenland polar bears (Ursus maritimus). Environ. Toxicol. Chem. 25 (2006) 1551-1557
54. Stapleton H.M., Alaee M., Letcher R.J., and Baker J.E. Debromination of flame retardant decabromodiphenyl ether by juvenile carp (Cyprinus carpio) following dietary exposure. Environ. Sci. Technol. 38 (2004) 112-119
55. Timme-Laragy A., Levin E., and Di Giulio R. Developmental and behavioral effects of embryonic exposure tot he polybrominated diphenylether mixture DE-71 in the killifish (Fundulus heteroclitus). Chemosphere 62 (2006) 1097-1104
56. Tjärnlunf U., Ericson G., Örn U., de Wit C., and Balk L. Effects of two polybrominated diphenyl ethers on rainbow trout (Oncorhynchus mykiss) exposed via food. Mar. Environ. Res. 46 (1998) 107-112
57. Tomy G., Palace V., Halldorson T., Braekevelt E., Danell R., Wautier K., Evans B., Brinkworth L., and Fisk A. Bioaccumulation, biotransformation and biochemical effects of brominated diphenyl ethers in juvenile lake trout (Salvelinus namaycush). Environ. Sci. Technol. 38 (2004) 1496-1504
58. Travacio M., Polo J.M., and Llesuy S. Chromium (VI) induces oxidative stress in the mouse brain. Toxicology 150 (2000) 137-146
59. van der Oost R., Beyer J., and Vermeulen N.P.E. Fish bioaccumulation and biomarkers in environmental risk assessment: a review. Environ. Toxicol. Pharmacol. 13 (2003) 57-149
60. Wang D. The uridine diphosphate glucuronosyltransferases: quantitative structure-activity relationships for hydroxyl polychlorinated biphenyl substances. Mol. Toxicol. 79 (2005) 554-560
61. Whitehead A., Anderson S.L., Ramirez A., and Wilson B.W. Cholinesterases in aquatic biomonitoring: assay optimization and species-specific characterization for a California native fish. Ecotoxicology 14 (2005) 597-606
62. Zar J.H. Biostatistical Analysis (1996), Prentice-Hall International, Inc., New Jersey
63. Zhou T., Ross D.G., DeVito M.J., and Crofton K.M. Effects of short-term in vivo exposure to polybrominated diphenyl ethers on thyroid hormones and hepatic enzyme activities in weanling rats. Toxicol. Sci. 61 (2001) 76-82
64. Zhou T., Taylor M.M., DeVito M.J., and Crofton K.M. Developmental exposure to brominated diphenyl ethers results in thyroid hormone disruption. Toxicol. Sci. 66 (2002) 105-116