Involvements of PHI-nitric oxide and PACAP-BK channel in the sustained relaxation of mouse gastric fundus

European Journal of Pharmacology

Volumn 590, Issue 1-3, 2008, Pages 80-86

  Hagi, Kiyomi ^a   Azuma, Yasu Taka ^a   Nakajima, Hidemitsu ^a   Shintani, Norihito ^b   Hashimoto, Hitoshi ^b,c   Baba, Akemichi ^b   Takeuchi, Tadayoshi ^a  

^a Osaka Prefecture University   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

BK channel; nitric oxide; PACAP; PACAP knockout mouse; PHI

Indexed keywords

ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; APAMIN; ATROPINE; GLIBENCLAMIDE; GUANETHIDINE; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; IBERIOTOXIN; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; N ACETYL S NITROSOPENICILLAMINE; N(G) NITROARGININE; NITRIC OXIDE; PEPTIDE HISTIDINE ISOLEUCINE; POTASSIUM CHANNEL;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTROSTIMULATION; FEMALE; IMMUNOREACTIVITY; KNOCKOUT MOUSE; MALE; MOUSE; MUSCLE RELAXATION; MYENTERIC PLEXUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; STOMACH FUNDUS; STOMACH MUSCLE;

ANIMALS; ELECTRIC STIMULATION; GASTRIC FUNDUS; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MALE; MICE; MICE, INBRED ICR; MUSCLE RELAXATION; NITRIC OXIDE; PEPTIDE PHI; PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; S-NITROSO-N-ACETYLPENICILLAMINE;

EID: 48049099910     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2008.05.045     Document Type: Article

References (46)

1. Baccari M.C., Bani D., Bigazzi M., and Calamai F. Influence of relaxin on the neurally induced relaxant responses of the mouse gastric fundus. Biol. Reprod. 71 (2004) 1325-1329
2. Baccari M.C., and Calamai F. Modulation of nitrergic relaxant responses by peptides in the mouse gastric fundus. Regul. Pept. 98 (2001) 27-32
3. Baccari M.C., Iacoviello C., and Calamai F. Nitric oxide as modulator of cholinergic neurotransmission in gastric muscle of rabbits. Am. J. Physiol. 273 (1997) G456-G463
4. Bruch L., Bychkov R., Kastner A., Bulow T., Ried C., Gollasch M., Baumann G., Luft F.C., and Haller H. Pituitary adenylate-cyclase-activating peptides relax human coronary arteries by activating K(ATP) and K(Ca) channels in smooth muscle cells. J. Vasc. Res. 34 (1997) 11-18
5. Bruch L., Rubel S., Kastner A., Gellert K., Gollasch M., and Witt C. Pituitary adenylate cyclase activating peptides relax human pulmonary arteries by opening of KATP and KCa channels. Thorax 53 (1998) 586-587
6. Calixto J.B., and Medeiros Y.S. Bradykinin-induced biphasic response in the rat isolated stomach fundus: functional evidence for a novel bradykinin receptor. Life Sci. 50 (1992) PL47-PL52
7. Curro D., De Marco T., and Preziosi P. Evidence for an apamin-sensitive, but not purinergic, component in the nonadrenergic noncholinergic relaxation of the rat gastric fundus. Br. J. Pharmacol. 143 (2004) 785-793
8. Curro D., and Preziosi P. Non-adrenergic non-cholinergic relaxation of the rat stomach. Gen. Pharmacol. 31 (1998) 697-703
9. Curro D., Preziosi P., Ragazzoni E., and Ciabattoni G. Peptide histidine isoleucine-like immunoreactivity release from the rat gastric fundus. Br. J. Pharmacol. 113 (1994) 541-549
10. De Man J.G., De Winter B.Y., Herman A.G., and Pelckmans P.A. Study on the cyclic GMP-dependency of relaxations to endogenous and exogenous nitric oxide in the mouse gastrointestinal tract. Br. J. Pharmacol. 150 (2007) 88-96
11. De Man J.G., Moreels T.G., De Winter B.Y., Herman A.G., and Pelckmans P.A. Pre- and postjunctional protective effect of neocuproine on the nitrergic neurotransmitter in the mouse gastric fundus. Br. J. Pharmacol. 132 (2001) 277-285
12. Dick J.M., Van Molle W., Brouckaert P., and Lefebvre R.A. Relaxation by vasoactive intestinal polypeptide in the gastric fundus of nitric oxide synthase-deficient mice. J. Physiol. 538 (2002) 133-143
13. Drahushuk K., Connell T.D., and Higgins D. Pituitary adenylate cyclase-activating polypeptide and vasoactive intestinal peptide inhibit dendritic growth in cultured sympathetic neurons. J. Neurosci. 22 (2002) 6560-6569
14. Ergun Y., and Ogulener N. Evidence for the interaction between nitric oxide and vasoactive intestinal polypeptide in the mouse gastric fundus. J. Pharmacol. Exp. Ther. 299 (2001) 945-950
15. Hay-Schmidt A., Grunnet M., Abrahamse S.L., Knaus H.G., and Klaerke D.A. Localization of Ca2+ -activated big-conductance K+ channels in rabbit distal colon. Pflugers Arch. 446 (2003) 61-68
16. Hiramatsu T., Kume H., Yamaki K., and Takagi K. Inhibition of pituitary adenylate cyclase activating polypeptide induced relaxation of guinea-pig tracheal smooth muscle by charybdotoxin. Arzneimittelforschung 45 (1995) 689-692
17. Jenkinson K.M., and Reid J.J. Evidence that adenosine 5'-triphosphate is the third inhibitory non-adrenergic non-cholinergic neurotransmitter in the rat gastric fundus. Br. J. Pharmacol. 130 (2000) 1627-1631
18. Katsoulis S., Schmidt W.E., Schwarzhoff R., Folsch U.R., Jin J.G., Grider J.R., and Makhlouf G.M. Inhibitory transmission in guinea pig stomach mediated by distinct receptors for pituitary adenylate cyclase-activating peptide. J. Pharmacol. Exp. Ther. 278 (1996) 199-204
19. Kim M., Han I.S., Koh S.D., and Perrino B.A. Roles of CaM kinase II and phospholamban in SNP-induced relaxation of murine gastric fundus smooth muscles. Am. J. Physiol. Cell Physiol. 291 (2006) C337-C347
20. Kishi M., Takeuchi T., Katayama H., Yamazaki Y., Nishio H., Hata F., and Takewaki T. Involvement of cyclic AMP-PKA pathway in VIP-induced, charybdotoxin-sensitive relaxation of longitudinal muscle of the distal colon of Wistar-ST rats. Br. J. Pharmacol. 129 (2000) 140-146
21. Kishi M., Takeuchi T., Suthamnatpong N., Ishii T., Nishio H., Hata F., and Takewaki T. VIP- and PACAP-mediated nonadrenergic, noncholinergic inhibition in longitudinal muscle of rat distal colon: involvement of activation of charybdotoxin- and apamin-sensitive K+ channels. Br. J. Pharmacol. 119 (1996) 623-630
22. Klemm M.F., and Lang R.J. Distribution of Ca2+-activated K+ channel (SK2 and SK3) immunoreactivity in intestinal smooth muscles of the guinea-pig. Clin. Exp. Pharmacol. Physiol. 29 (2002) 18-25
23. Kortezova N.I., Shikova L.I., Milusheva E.A., Itzev D.E., Bagaev V.A., and Mizhorkova Z.N. Muscarinic modulation of nitrergic neurotransmission in guinea-pig gastric fundus. Neurogastroenterol. Motil. 16 (2004) 155-165
24. Kunze W.A., Bornstein J.C., Furness J.B., Hendriks R., and Stephenson D.S. Charybdotoxin and iberiotoxin but not apamin abolish the slow after-hyperpolarization in myenteric plexus neurons. Pflugers Arch. 428 (1994) 300-306
25. Lang R.J., Harvey J.R., McPhee G.J., and Klemm M.F. Nitric oxide and thiol reagent modulation of Ca2+-activated K+ (BKCa) channels in myocytes of the guinea-pig taenia caeci. J. Physiol. 525 Pt 2 (2000) 363-376
26. Lefebvre R.A. Non-adrenergic non-cholinergic neurotransmission in the proximal stomach. Gen. Pharmacol. 24 (1993) 257-266
27. Lefebvre R.A., and Horacek J. Relaxant effects of BRL 38227 and pinacidil on the rat gastric fundus. Eur. J. Pharmacol. 214 (1992) 1-6
28. Lefebvre R.A., Smits G.J., and Timmermans J.P. Study of NO and VIP as non-adrenergic non-cholinergic neurotransmitters in the pig gastric fundus. Br. J. Pharmacol. 116 (1995) 2017-2026
29. Lefebvre R.A., and Vandekerckhove K. Effect of nitroglycerin and long-term electrical stimulation on nitrergic relaxation in the pig gastric fundus. Br. J. Pharmacol. 123 (1998) 143-149
30. Mashimo H., He X.D., Huang P.L., Fishman M.C., and Goyal R.K. Neuronal constitutive nitric oxide synthase is involved in murine enteric inhibitory neurotransmission. J. Clin. Invest. 98 (1996) 8-13
31. Mukai K., Takeuchi T., Toyoshima M., Satoh Y., Fujita A., Shintani N., Hashimoto H., Baba A., and Hata F. PACAP- and PHI-mediated sustained relaxation in circular muscle of gastric fundus: findings obtained in PACAP knockout mice. Regul. Pept. 133 (2006) 54-61
32. Mule F., and Serio R. NANC inhibitory neurotransmission in mouse isolated stomach: involvement of nitric oxide, ATP and vasoactive intestinal polypeptide. Br. J. Pharmacol. 140 (2003) 431-437
33. Ren J., and Galligan J.J. Dynamics of fast synaptic excitation during trains of stimulation in myenteric neurons of guinea-pig ileum. Auton. Neurosci. 117 (2005) 67-78
34. Sah P., and Faber E.S. Channels underlying neuronal calcium-activated potassium currents. Prog. Neurobiol. 66 (2002) 345-353
35. Sausbier M., Matos J.E., Sausbier U., Beranek G., Arntz C., Neuhuber W., Ruth P., and Leipziger J. Distal colonic K(+) secretion occurs via BK channels. J. Am. Soc. Nephrol. 17 (2006) 1275-1282
36. Selemidis S., and Cocks T.M. Nitrergic relaxation of the mouse gastric fundus is mediated by cyclic GMP-dependent and ryanodine-sensitive mechanisms. Br. J. Pharmacol. 129 (2000) 1315-1322
37. Stengel P.W., and Cohen M.L. M1 receptor-mediated nitric oxide-dependent relaxation unmasked in stomach fundus from M3 receptor knockout mice. J. Pharmacol. Exp. Ther. 304 (2003) 675-682
38. Takahashi T., and Owyang C. Vagal control of nitric oxide and vasoactive intestinal polypeptide release in the regulation of gastric relaxation in rat. J. Physiol. 484 Pt 2 (1995) 481-492
39. Takeuchi T., Kishi M., Hirayama N., Yamaji M., Ishii T., Nishio H., Hata F., and Takewaki T. Tyrosine kinase involvement in apamin-sensitive inhibitory responses of rat distal colon. J. Physiol. 514 Pt 1 (1999) 177-188
40. Takeuchi T., Toyoshima M., Mukai K., Hagi K., Matsui M., Nakajima H., Azuma Y.T., and Hata F. Involvement of M(2) muscarinic receptors in relaxant response of circular muscle of mouse gastric antrum. Neurogastroenterol. Motil. 18 (2006) 226-233
41. Toyoshima M., Takeuchi T., Goto H., Mukai K., Shintani N., Hashimoto H., Baba A., and Hata F. Roles of PACAP and PHI as inhibitory neurotransmitters in the circular muscle of mouse antrum. Pflugers Arch. 451 (2006) 559-568
42. Vetri T., Bonvissuto F., Marino A., and Postorino A. Nitrergic and purinergic interplay in inhibitory transmission in rat gastric fundus. Auton. Autacoid. Pharmacol. 27 (2007) 151-157
43. Vogalis F. Potassium channels in gastrointestinal smooth muscle. J. Auton. Pharmacol. 20 (2000) 207-219
44. Waseda K., Takeuchi T., Ohta M., Okishio Y., Fujita A., Hata F., and Takewaki T. Participation of ATP in nonadrenergic, noncholinergic relaxation of longitudinal muscle of wistar rat jejunum. J. Pharmacol. Sci. 97 (2005) 91-100
45. Weiger T.M., Hermann A., and Levitan I.B. Modulation of calcium-activated potassium channels. J. Comp. Physiol. A Neuroethol. Sens. Neural. Behav. Physiol. 188 (2002) 79-87
46. Zizzo M.G., Mule F., and Serio R. Interplay between PACAP and NO in mouse ileum. Neuropharmacology 46 (2004) 449-455