메뉴 건너뛰기




Volumn 9, Issue 2, 2008, Pages 69-82

Effect of S-adenosylmethionine tablets on the reduction of age-related mental decline in dogs: A double-blinded, placebo-controlled trial

Author keywords

[No Author keywords available]

Indexed keywords

S ADENOSYLMETHIONINE;

EID: 48049094157     PISSN: 15283593     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (32)

References (46)
  • 2
    • 0025707456 scopus 로고
    • Behavioral problems in old dogs: 26 cases ( 1984-1987)
    • Chapman BL, Voith VL. Behavioral problems in old dogs: 26 cases ( 1984-1987). JAVMA 1990;196:944-946.
    • (1990) JAVMA , vol.196 , pp. 944-946
    • Chapman, B.L.1    Voith, V.L.2
  • 3
    • 0002479840 scopus 로고    scopus 로고
    • Canine cognitive dysfunction
    • Dodman NH, Shuster L, eds, Hoboken, NJ: Blackwell Science;
    • Ruehl WW, Hart BL. Canine cognitive dysfunction. In: Dodman NH, Shuster L, eds. Psychopharmacology of Animal Behavior Disorders. Hoboken, NJ: Blackwell Science; 1998:283-304.
    • (1998) Psychopharmacology of Animal Behavior Disorders , pp. 283-304
    • Ruehl, W.W.1    Hart, B.L.2
  • 4
    • 0035379688 scopus 로고    scopus 로고
    • Predicting behavioral changes associated with age-related cognitive impairment in dogs
    • Bain MJ, Hart BL, Cliff KD, Ruehl WW. Predicting behavioral changes associated with age-related cognitive impairment in dogs. JAVMA 2001;218:1792-1795.
    • (2001) JAVMA , vol.218 , pp. 1792-1795
    • Bain, M.J.1    Hart, B.L.2    Cliff, K.D.3    Ruehl, W.W.4
  • 5
    • 0035377333 scopus 로고    scopus 로고
    • Prevalence of behavioral changes associated with age-related cognitive impairment in dogs
    • Neilson JC, Hart BL, Cliff KD, Ruehl WW. Prevalence of behavioral changes associated with age-related cognitive impairment in dogs. JAVMA 2001;218:1787-1791.
    • (2001) JAVMA , vol.218 , pp. 1787-1791
    • Neilson, J.C.1    Hart, B.L.2    Cliff, K.D.3    Ruehl, W.W.4
  • 6
    • 48049085265 scopus 로고    scopus 로고
    • Chronic dysfunction syndrome among manageable behavioral problems
    • Kahler S. Chronic dysfunction syndrome among manageable behavioral problems. JAVMA 2005;227: 863-864.
    • (2005) JAVMA , vol.227 , pp. 863-864
    • Kahler, S.1
  • 7
    • 0027332522 scopus 로고
    • β-Amyloid accumulation in aged canine brain: A model of early plaque formation in Alzheimer's disease
    • Cummings BJ, Su JH, Cotman CW, et al. β-Amyloid accumulation in aged canine brain: a model of early plaque formation in Alzheimer's disease. Neurobiol Aging 1993;14:547-560.
    • (1993) Neurobiol Aging , vol.14 , pp. 547-560
    • Cummings, B.J.1    Su, J.H.2    Cotman, C.W.3
  • 8
    • 0033125493 scopus 로고    scopus 로고
    • Age-related changes in the brain of the dog
    • Borras D, Ferret I, Pumarola M. Age-related changes in the brain of the dog. Vet Pathol 1999;36:202-211.
    • (1999) Vet Pathol , vol.36 , pp. 202-211
    • Borras, D.1    Ferret, I.2    Pumarola, M.3
  • 9
    • 0036828353 scopus 로고    scopus 로고
    • S-adenosyl-L-methionine (SAMe): From the bench to the bedside-molecular basis of a pleiotropic molecule
    • Bottiglieri T. S-adenosyl-L-methionine (SAMe): from the bench to the bedside-molecular basis of a pleiotropic molecule. Am J Clin Nutr 2002;76,1151S-1157S.
    • (2002) Am J Clin Nutr , vol.76
    • Bottiglieri, T.1
  • 10
    • 2942673042 scopus 로고    scopus 로고
    • S-adenosyl-methionine in depression: A comprehensive review of the literature
    • Papakostas GI, Alpert JE, Fava M. S-adenosyl-methionine in depression: a comprehensive review of the literature. Curr Psychiatry Rep 2003;5:460-466.
    • (2003) Curr Psychiatry Rep , vol.5 , pp. 460-466
    • Papakostas, G.I.1    Alpert, J.E.2    Fava, M.3
  • 11
    • 0036829068 scopus 로고    scopus 로고
    • Role of S-adenosyl-L-methionine in the treatment of depression: A review of the evidence
    • Mischoulon D, Fava M. Role of S-adenosyl-L-methionine in the treatment of depression: a review of the evidence. Am J Clin Nutr 2002;76:1158S-1161S.
    • (2002) Am J Clin Nutr , vol.76
    • Mischoulon, D.1    Fava, M.2
  • 12
    • 0036526714 scopus 로고    scopus 로고
    • S-adenosylmethionine and depression
    • Nguyen M, Gregan A. S-adenosylmethionine and depression. Aust Fam Physician 2002;31:339-343.
    • (2002) Aust Fam Physician , vol.31 , pp. 339-343
    • Nguyen, M.1    Gregan, A.2
  • 13
    • 0028102526 scopus 로고
    • The clinical potential of ademetionine (S-adenosylmethionine) in neurological disorders
    • Bottiglieri T, Hyland K, Reynolds EH. The clinical potential of ademetionine (S-adenosylmethionine) in neurological disorders. Drugs 1994;45:137-152.
    • (1994) Drugs , vol.45 , pp. 137-152
    • Bottiglieri, T.1    Hyland, K.2    Reynolds, E.H.3
  • 14
    • 0028320572 scopus 로고
    • S-adenosylmethionine levels in psychiatric and neurological disorders: A review
    • Bottiglieri T, Hyland K. S-adenosylmethionine levels in psychiatric and neurological disorders: a review. Acta Neurol Scand 1994; 154:19-26.
    • (1994) Acta Neurol Scand , vol.154 , pp. 19-26
    • Bottiglieri, T.1    Hyland, K.2
  • 15
    • 0029799427 scopus 로고    scopus 로고
    • Brain S-adenosylmethionine levels are severely decreased in Alzheimer's disease
    • Morrison LD, Smith DD, Kish SJ. Brain S-adenosylmethionine levels are severely decreased in Alzheimer's disease. J Neurochem 1996;67:1328-1331.
    • (1996) J Neurochem , vol.67 , pp. 1328-1331
    • Morrison, L.D.1    Smith, D.D.2    Kish, S.J.3
  • 16
    • 0025606597 scopus 로고
    • Cerebrospinal fluid S-adenosylmethionine in depression and dementia: Effects of treatment with parenteral and oral S-adenosylmethionine
    • Bottiglieri T, Godfrey P, Flynn T, et al. Cerebrospinal fluid S-adenosylmethionine in depression and dementia: effects of treatment with parenteral and oral S-adenosylmethionine. J Neurol Neurosurg Psychiatry 1990;53: 1096-1098.
    • (1990) J Neurol Neurosurg Psychiatry , vol.53 , pp. 1096-1098
    • Bottiglieri, T.1    Godfrey, P.2    Flynn, T.3
  • 17
    • 0000728520 scopus 로고
    • S-adenosylmethionine and Alzheimer's disease
    • Reynolds EH, Godfrey P, Bottiglieri T, et al. S-adenosylmethionine and Alzheimer's disease. Neurology 1989;39(Suppl 1):397.
    • (1989) Neurology , vol.39 , Issue.SUPPL. 1 , pp. 397
    • Reynolds, E.H.1    Godfrey, P.2    Bottiglieri, T.3
  • 18
    • 0028362386 scopus 로고
    • Effects of S-adenosyl-L-methionine on cognitive and vigilance functions in the elderly
    • Fontanari D, DiPalma C, Giorgetti G, et al. Effects of S-adenosyl-L-methionine on cognitive and vigilance functions in the elderly. Curr Ther Res Clin Exp 1994;55: 682-689.
    • (1994) Curr Ther Res Clin Exp , vol.55 , pp. 682-689
    • Fontanari, D.1    DiPalma, C.2    Giorgetti, G.3
  • 19
    • 0028331373 scopus 로고
    • Cognitive functions and aging in the dog: Acquisition of non-spatial visual tasks
    • Milgram NW, Head E, Weiner E, Thomas E. Cognitive functions and aging in the dog: acquisition of non-spatial visual tasks. Behav Neurosci 1994;108:57-68.
    • (1994) Behav Neurosci , vol.108 , pp. 57-68
    • Milgram, N.W.1    Head, E.2    Weiner, E.3    Thomas, E.4
  • 20
    • 0013015637 scopus 로고    scopus 로고
    • Size and reversal learning in the beagle dog as a measure of executive function and inhibitory control in aging
    • Tapp PD, Siwak CT, Estrada J, et al. Size and reversal learning in the beagle dog as a measure of executive function and inhibitory control in aging. Learn Mem 2003;10:64-73.
    • (2003) Learn Mem , vol.10 , pp. 64-73
    • Tapp, P.D.1    Siwak, C.T.2    Estrada, J.3
  • 21
    • 2342544886 scopus 로고    scopus 로고
    • Long term treatment with antioxidants and a program of behavioral enrichment reduces age-dependant impairment in discrimination and reversal learning in beagle dogs
    • Milgram NW, Head EA, Zicker SC, et al. Long term treatment with antioxidants and a program of behavioral enrichment reduces age-dependant impairment in discrimination and reversal learning in beagle dogs. Exp Gerontol 2004;39:753-765.
    • (2004) Exp Gerontol , vol.39 , pp. 753-765
    • Milgram, N.W.1    Head, E.A.2    Zicker, S.C.3
  • 22
    • 0029564645 scopus 로고
    • Canine cognitive dysfunction as a model for human age-related cognitive decline, dementia and Alzheimer's disease: Clinical presentation, cognitive testing, pathology and response to l-deprenyl therapy
    • Ruehl WW, Bruyette DS, De Paoli A, et al. Canine cognitive dysfunction as a model for human age-related cognitive decline, dementia and Alzheimer's disease: clinical presentation, cognitive testing, pathology and response to l-deprenyl therapy. Prog Brain Res 1995;106:217-225.
    • (1995) Prog Brain Res , vol.106 , pp. 217-225
    • Ruehl, W.W.1    Bruyette, D.S.2    De Paoli, A.3
  • 23
    • 0036752043 scopus 로고    scopus 로고
    • Dietary enrichment counteracts age-associated cognitive dysfunction in canines
    • Milgram NW, Zicker SC, Head EA, et al. Dietary enrichment counteracts age-associated cognitive dysfunction in canines. Neurobiol Aging 2002;23:737-745.
    • (2002) Neurobiol Aging , vol.23 , pp. 737-745
    • Milgram, N.W.1    Zicker, S.C.2    Head, E.A.3
  • 24
    • 42649127765 scopus 로고    scopus 로고
    • Improvement of short term memory performance in aged beagles by a neutraceutical supplement containing phosphatidylserine, Ginkgo biloba, vitamin E and pyridoxine
    • Araujo J, Landsberg GM, Milgram NW, Miolo A. Improvement of short term memory performance in aged beagles by a neutraceutical supplement containing phosphatidylserine, Ginkgo biloba, vitamin E and pyridoxine. Can Vet J 2008;49:379-385.
    • (2008) Can Vet J , vol.49 , pp. 379-385
    • Araujo, J.1    Landsberg, G.M.2    Milgram, N.W.3    Miolo, A.4
  • 25
    • 85044705316 scopus 로고    scopus 로고
    • Use of client-specific outcome measures to assess treatment effects in geriatric, arthritic dogs: Controlled clinical evaluation of a nutraceutical
    • Gingerich DA, Strobel JD. Use of client-specific outcome measures to assess treatment effects in geriatric, arthritic dogs: controlled clinical evaluation of a nutraceutical. Vet Ther 2003;4:56-66.
    • (2003) Vet Ther , vol.4 , pp. 56-66
    • Gingerich, D.A.1    Strobel, J.D.2
  • 26
    • 0028100302 scopus 로고
    • S-adenosyl-L-methionine normalizes P300 latency in patients with major depression
    • Torta R, Borio R, Cicolin A, et al. S-adenosyl-L-methionine normalizes P300 latency in patients with major depression. Curr Ther Res Clin Exp 1994;55:864-874.
    • (1994) Curr Ther Res Clin Exp , vol.55 , pp. 864-874
    • Torta, R.1    Borio, R.2    Cicolin, A.3
  • 27
    • 0036921639 scopus 로고    scopus 로고
    • Pharmacodynamic studies on the central mode of action of S-adenosyl-L-methionine (SAMe) infusions in elderly subjects, utilizing EEG mapping and psychometry
    • Saletu B, Anderer P, Linzmayer L, et al. Pharmacodynamic studies on the central mode of action of S-adenosyl-L-methionine (SAMe) infusions in elderly subjects, utilizing EEG mapping and psychometry. J Neural Transm 2002;109:1505-1526.
    • (2002) J Neural Transm , vol.109 , pp. 1505-1526
    • Saletu, B.1    Anderer, P.2    Linzmayer, L.3
  • 28
    • 24044433528 scopus 로고    scopus 로고
    • Double-blind, placebo-controlled pharmacodynamic studies with a nutraceutical dose of ademetionine (SAMe) in elderly subjects, utilizing EEG mapping and psychometry
    • Arnold O, Saletu B, Anderer P, et al. Double-blind, placebo-controlled pharmacodynamic studies with a nutraceutical dose of ademetionine (SAMe) in elderly subjects, utilizing EEG mapping and psychometry. Eur Neuropsychopharmacol 2005;15:533-543.
    • (2005) Eur Neuropsychopharmacol , vol.15 , pp. 533-543
    • Arnold, O.1    Saletu, B.2    Anderer, P.3
  • 29
    • 0036830204 scopus 로고    scopus 로고
    • Electrophysiological neuroimaging of the central effects of S-adenosyl-L-methionine by mapping of electroencephalograms and event-related potentials and low-resolution brain electromagnetic tomography
    • Saletu B, Anderer P, Di Padova C, et al. Electrophysiological neuroimaging of the central effects of S-adenosyl-L-methionine by mapping of electroencephalograms and event-related potentials and low-resolution brain electromagnetic tomography. Am J Clin Nutr 2002;76(Supplement): 1162S-1171S.
    • (2002) Am J Clin Nutr , vol.76 , Issue.SUPPL.EMENT
    • Saletu, B.1    Anderer, P.2    Di Padova, C.3
  • 30
    • 0028189416 scopus 로고
    • S-adenosyl-l-methionine (SAMe) as anti-depressant: Meta-analysis of clinical studies
    • Bressa GM. S-adenosyl-l-methionine (SAMe) as anti-depressant: meta-analysis of clinical studies. Acta Neural Scand 1994;154(Supplement):7-14.
    • (1994) Acta Neural Scand , vol.154 , Issue.SUPPL.EMENT , pp. 7-14
    • Bressa, G.M.1
  • 31
    • 0036828360 scopus 로고    scopus 로고
    • Efficacy and tolerability of oral and intramuscular S-adenosyl-L-methione 1,4-butanedisulfonate (SAMe) in the treatment of major depression: Comparison with imipramine in 2 multicentre studies
    • Delle Chiaie R, Pancheri R, Scapicchio P. Efficacy and tolerability of oral and intramuscular S-adenosyl-L-methione 1,4-butanedisulfonate (SAMe) in the treatment of major depression: comparison with imipramine in 2 multicentre studies. Am J Clin Nutr 2002;76(Suppl): 1172S-1176S.
    • (2002) Am J Clin Nutr , vol.76 , Issue.SUPPL.
    • Delle Chiaie, R.1    Pancheri, R.2    Scapicchio, P.3
  • 33
    • 0002301763 scopus 로고
    • Changes in rat brain noradrenaline and serotonin metabolism after administration of S-adenosylmethionine
    • Zappia V, Usdin E, Salvatore S, eds, New York, NY: Pergamon Press;
    • Algeri S, Catto E, Curcio M, Coll E. Changes in rat brain noradrenaline and serotonin metabolism after administration of S-adenosylmethionine. In: Zappia V, Usdin E, Salvatore S, eds. Biochemical and Pharmacological Roles of Adenosylmethionine and the Central Nervous System. New York, NY: Pergamon Press; 1979:81-87.
    • (1979) Biochemical and Pharmacological Roles of Adenosylmethionine and the Central Nervous System , pp. 81-87
    • Algeri, S.1    Catto, E.2    Curcio, M.3    Coll, E.4
  • 34
    • 0024335021 scopus 로고
    • Acute changes in 5-HT metabolism after S-adenosy-L-methionine administration
    • Otero-Losada ME, Rubio MC. Acute changes in 5-HT metabolism after S-adenosy-L-methionine administration. Gen Pharmacol 1989;20:403-406.
    • (1989) Gen Pharmacol , vol.20 , pp. 403-406
    • Otero-Losada, M.E.1    Rubio, M.C.2
  • 35
    • 0024505014 scopus 로고
    • Acute effects of S-adenosylmethionine on catecholaminergic central functions
    • Otero-Losada ME, Rubio MC. Acute effects of S-adenosylmethionine on catecholaminergic central functions. Eur J Pharmacol 1990;163:353-356.
    • (1990) Eur J Pharmacol , vol.163 , pp. 353-356
    • Otero-Losada, M.E.1    Rubio, M.C.2
  • 36
    • 0021347893 scopus 로고
    • Age-related modification of dopaminergic and β-adrenergic receptor system: Restoration to normal activity by modifying membrane fluidity with S-adenosylmethionine
    • Cimino S, Vantini G, Algeri S, et al. Age-related modification of dopaminergic and β-adrenergic receptor system: restoration to normal activity by modifying membrane fluidity with S-adenosylmethionine. Life Sci 1984;34:2029-2039.
    • (1984) Life Sci , vol.34 , pp. 2029-2039
    • Cimino, S.1    Vantini, G.2    Algeri, S.3
  • 37
    • 0024396615 scopus 로고
    • Effects of a novel antidepressant S-adenosyl-methionine on α1- and β-adrenoreceptors in rat brain
    • Cohen BM, Stramentinoli G, Sosa AL, et al. Effects of a novel antidepressant S-adenosyl-methionine on α1- and β-adrenoreceptors in rat brain. Eur J Pharmacol 1989; 170:201-207.
    • (1989) Eur J Pharmacol , vol.170 , pp. 201-207
    • Cohen, B.M.1    Stramentinoli, G.2    Sosa, A.L.3
  • 38
    • 0026800648 scopus 로고
    • Effects of S-adenosyl-L-methionine on brain muscarinic receptors of aged rats
    • Muccioli G, Scordamaglia A, Bertacco S, Di Carlo R. Effects of S-adenosyl-L-methionine on brain muscarinic receptors of aged rats. Eur J Pharmacol 1992;227:293-299.
    • (1992) Eur J Pharmacol , vol.227 , pp. 293-299
    • Muccioli, G.1    Scordamaglia, A.2    Bertacco, S.3    Di Carlo, R.4
  • 39
    • 0024369661 scopus 로고
    • S-adenosyl-L-methionine restores prolactin receptors in the aged rabbit brain
    • Muccioli G, Di Carlo R. S-adenosyl-L-methionine restores prolactin receptors in the aged rabbit brain. Eur J Pharmacol 1989;166:223-230.
    • (1989) Eur J Pharmacol , vol.166 , pp. 223-230
    • Muccioli, G.1    Di Carlo, R.2
  • 40
    • 0023614366 scopus 로고
    • S-adenosylmethionine in the treatment of osteoarthritis, review of the clinical studies
    • Di Padova C. S-adenosylmethionine in the treatment of osteoarthritis, review of the clinical studies. Am J Med 1987;83:60-65.
    • (1987) Am J Med , vol.83 , pp. 60-65
    • Di Padova, C.1
  • 41
    • 0023625313 scopus 로고
    • A long-term (two years) clinical trial with S-adenosylmethionine for the treatment of osteoarthritis
    • König B. A long-term (two years) clinical trial with S-adenosylmethionine for the treatment of osteoarthritis. Am J Med 1987;83:89-94.
    • (1987) Am J Med , vol.83 , pp. 89-94
    • König, B.1
  • 42
    • 0023633682 scopus 로고
    • Double-blind clinical trial of S-adenosylmethionine versus ibuprofen in the treatment of osteoarthritis
    • Müller-Fassbender H. Double-blind clinical trial of S-adenosylmethionine versus ibuprofen in the treatment of osteoarthritis. Am J Med 1987;83:81-83.
    • (1987) Am J Med , vol.83 , pp. 81-83
    • Müller-Fassbender, H.1
  • 43
    • 44949221323 scopus 로고    scopus 로고
    • S-adenosyl methionine (SAMe) versus celecoxib for the treatment of osteoarthritis symptoms: A double-blind cross-over trial
    • Naim WI, Reinsch S, Hoehlet F, et al. S-adenosyl methionine (SAMe) versus celecoxib for the treatment of osteoarthritis symptoms: a double-blind cross-over trial. BMC Musculoskelet Disord 2004;26:5-6.
    • (2004) BMC Musculoskelet Disord , vol.26 , pp. 5-6
    • Naim, W.I.1    Reinsch, S.2    Hoehlet, F.3
  • 44
    • 0023630758 scopus 로고
    • Pharmacologic aspects of S-adenosylmethionine. Pharmacokinetics and pharmacodynamics
    • Stramentinoli G. Pharmacologic aspects of S-adenosylmethionine. Pharmacokinetics and pharmacodynamics. Am J Med 1987;83(Suppl 5A):35-42.
    • (1987) Am J Med , vol.83 , Issue.SUPPL. 5A , pp. 35-42
    • Stramentinoli, G.1
  • 45
    • 0023613967 scopus 로고
    • Effect of S-adenosylmethionine on experimental osteoarthritis in rabbits
    • Barcelo HA, Wiemeyer JC, Sagasta CL, et al. Effect of S-adenosylmethionine on experimental osteoarthritis in rabbits. Am J Med 1987;83(Suppl 5A):55-59.
    • (1987) Am J Med , vol.83 , Issue.SUPPL. 5A , pp. 55-59
    • Barcelo, H.A.1    Wiemeyer, J.C.2    Sagasta, C.L.3
  • 46
    • 0030795285 scopus 로고    scopus 로고
    • SAMe restores the changes in the proliferation and in the synthesis of fibronectin and proteoglycans induced by tumour necrosis factor alpha on cultured rabbit synovial cells
    • Gutierrez S, Palacios I, Sanchez-Pernaute O, et al. SAMe restores the changes in the proliferation and in the synthesis of fibronectin and proteoglycans induced by tumour necrosis factor alpha on cultured rabbit synovial cells. Br J Rheumatol 1997;36:27-31.
    • (1997) Br J Rheumatol , vol.36 , pp. 27-31
    • Gutierrez, S.1    Palacios, I.2    Sanchez-Pernaute, O.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.