Effect of storage conditions on compaction behavior of two grades of spray-dried lactose

Pharmaceutical Development and Technology

Volumn 13, Issue 4, 2008, Pages 277-282

  Atassi, Faraj ^a   Almaya, Ahmad ^a   Aburub, Aktham ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

Compaction; Spray dried lactose; Storage conditions; XRPD

Indexed keywords

LACTOSE;

ARTICLE; CRYSTALLIZATION; DIFFERENTIAL SCANNING CALORIMETRY; MOISTURE; PRIORITY JOURNAL; TABLET COMPRESSION; TABLET FORMULATION; X RAY POWDER DIFFRACTION;

CHEMISTRY, PHARMACEUTICAL; CRYSTALLIZATION; DRUG STABILITY; DRUG STORAGE; EXCIPIENTS; HUMIDITY; LACTOSE; POWDERS; TABLETS;

EID: 47949123688     PISSN: 10837450     EISSN: 10979867     Source Type: Journal    
DOI: 10.1080/10837450802088539     Document Type: Article

References (12)

1. Lerk CF, Andreae AC, de Boer AH. Alteration of α-lactose during differential scanning calorimetry. J Pharm Sci. 1984;73(6):856-857.
2. Drapier-Beche N, Fanni J, Parmentier M, Vilasi M. Evaluation of lactose crystalline forms by nondestructive analysis. J Dairy Sci. 1997;80(3):457-463.
3. Haque MK, Roos YH. Crystallization and X-ray diffraction of spray-dried and freeze-dried amorphous lactose. Carbohydr Res. 2005;340(2):293-301.
4. Schmitt EA, Law D, Zhang GGZ. Nucleation and crystallization kinetics of hydrated amorphous lactose above glass transition temperature. J Pharm Sci. 1999;88(3),:291-296.
5. Jouppila K, Kansikas J, Roos YH. Crystallization and X-ray diffraction of crystals formed in water-plasticized amorphous lactose. Biotechnol Prog. 1998;14(2):347-350.
6. Sebhatu T, Elamin AA, Ahlneck G. Effect of moisture sorption on tableting characteristics of spray dried (15% amorphous) lactose. Pharm Res. 1994;11(9):1233-1238.
7. Busignies V, Tchoreloff P, Leclerc B, Hersen C, Keller G, Gouarraze G. Compaction of crystallographic forms of pharmaceutical granular lactose. II. Compacts mechanical properties. Eur J Pharm Biopharm. 2004;58(3):577-586.
8. Gombas A, Szabo-Revesz P, Kata M, Regdon Jr. G, Eros I. Quantitative determination of crystallinity of α-lactose monohydrate by DSC. J Therm Anal Calorim. 2002;68(2):503-510.
9. Chen X, Bates S, Morris KR. Quantifying amorphous content of lactose using parallel beam X-ray powder diffraction and whole pattern fitting. J Pharm Biomed Anal. 2001;26(1):63-72.
10. Joiris E, Martino PD, Berneron C, Guyot-Hermann AM, Gutot JS. Compression behavior of orthorhombic paracetamol. Pharm Res. 1998;15(7):1122.
11. Fell JT, Newton JM. Determination of tablet Strength by the diametral-compression test. J Pharm sci. 190;59(5):688.
12. Sugimoto M, Narisawa S, Matsubara K, Yoshino H, Nakano M, Handa T. Development of manufacturing method for rapidly disintegrating oral tablet using the crystalline transition of amorphous sucrose. Int J Pharm. 2006;320(1-2):71-78.