메뉴 건너뛰기




Volumn 7, Issue 2, 2008, Pages 314-325

An enhancer/promoter combination strengthens the expression of blood-coagulation factor VIII in non-viral expression vectors

Author keywords

Coagulation; Enhancer HCR 1 and HCR 2; Human factor VIII; Liver specific promoter; Mammalian cell lines; Plasmid vector

Indexed keywords

ALPHA 1 ANTITRYPSIN; BLOOD CLOTTING FACTOR 8; ELONGATION FACTOR 1ALPHA; PLASMID VECTOR;

EID: 47949090032     PISSN: None     EISSN: 16765680     Source Type: Journal    
DOI: 10.4238/vol7-2gmr447     Document Type: Article
Times cited : (9)

References (28)
  • 1
    • 0028825717 scopus 로고
    • Evolutionary duplication of a hepatic control region in the human apolipoprotein E gene locus. Identification of a second region that confers high level and liver-specific expression of the human apolipoprotein E gene in transgenic mice
    • Allan CM, Walker D and Taylor JM (1995). Evolutionary duplication of a hepatic control region in the human apolipoprotein E gene locus. Identification of a second region that confers high level and liver-specific expression of the human apolipoprotein E gene in transgenic mice. J. Biol. Chem. 270: 26278-26281.
    • (1995) J. Biol. Chem , vol.270 , pp. 26278-26281
    • Allan, C.M.1    Walker, D.2    Taylor, J.M.3
  • 3
    • 0022975486 scopus 로고    scopus 로고
    • Burke RL, Pachl C, Quiroga M, Rosenberg S, et al. (1986). The functional domains of coagulation factor VIII:C. J. Biol. Chem. 261: 12574-12578.
    • Burke RL, Pachl C, Quiroga M, Rosenberg S, et al. (1986). The functional domains of coagulation factor VIII:C. J. Biol. Chem. 261: 12574-12578.
  • 4
    • 34548796475 scopus 로고    scopus 로고
    • The enhancing effects of the light chain on heavy chain secretion in split delivery of factor VIII gene
    • Chen L, Zhu F, Li J, Lu H, et al. (2007). The enhancing effects of the light chain on heavy chain secretion in split delivery of factor VIII gene. Mol. Ther. 15: 1856-1862.
    • (2007) Mol. Ther , vol.15 , pp. 1856-1862
    • Chen, L.1    Zhu, F.2    Li, J.3    Lu, H.4
  • 5
    • 33750825113 scopus 로고    scopus 로고
    • The protein structure and effect of factor VIII
    • Fang H, Wang L and Wang H (2007). The protein structure and effect of factor VIII. Thromb. Res. 119: 1-13.
    • (2007) Thromb. Res , vol.119 , pp. 1-13
    • Fang, H.1    Wang, L.2    Wang, H.3
  • 6
    • 0021750055 scopus 로고
    • Characterization of the human factor VIII gene
    • Gitschier J, Wood WI, Goralka TM, Wion KL, et al. (1984). Characterization of the human factor VIII gene. Nature 312: 326-330.
    • (1984) Nature , vol.312 , pp. 326-330
    • Gitschier, J.1    Wood, W.I.2    Goralka, T.M.3    Wion, K.L.4
  • 7
    • 0027992935 scopus 로고
    • Quantitative evaluation of liver-specific promoters from retroviral vectors after in vivo transduction of hepatocytes
    • Hafenrichter DG, Wu X, Rettinger SD, Kennedy SC, et al. (1994a). Quantitative evaluation of liver-specific promoters from retroviral vectors after in vivo transduction of hepatocytes. Blood 84: 3394-3404.
    • (1994) Blood , vol.84 , pp. 3394-3404
    • Hafenrichter, D.G.1    Wu, X.2    Rettinger, S.D.3    Kennedy, S.C.4
  • 8
    • 0028300832 scopus 로고
    • Liver-directed gene therapy: Evaluation of liver specific promoter elements
    • Hafenrichter DG, Ponder KP, Rettinger SD, Kennedy SC, et al. (1994b). Liver-directed gene therapy: evaluation of liver specific promoter elements. J. Surg. Res. 56: 510-517.
    • (1994) J. Surg. Res , vol.56 , pp. 510-517
    • Hafenrichter, D.G.1    Ponder, K.P.2    Rettinger, S.D.3    Kennedy, S.C.4
  • 9
    • 0028078717 scopus 로고
    • Hemophilia A
    • Hoyer LW (1994). Hemophilia A. N. Engl. J. Med. 330: 38-47.
    • (1994) N. Engl. J. Med , vol.330 , pp. 38-47
    • Hoyer, L.W.1
  • 10
    • 0036547749 scopus 로고    scopus 로고
    • Gene regulation of the serine proteinase inhibitors alpha1-antitrypsin and alpha1-antichymotrypsin
    • Kalsheker N, Morley S and Morgan K (2002). Gene regulation of the serine proteinase inhibitors alpha1-antitrypsin and alpha1-antichymotrypsin. Biochem. Soc. Trans. 30: 93-98.
    • (2002) Biochem. Soc. Trans , vol.30 , pp. 93-98
    • Kalsheker, N.1    Morley, S.2    Morgan, K.3
  • 11
    • 0023918719 scopus 로고
    • Synthesis, processing, and secretion of recombinant human factor VIII expressed in mammalian cells
    • Kaufman RJ, Wasley LC and Dorner AJ (1988). Synthesis, processing, and secretion of recombinant human factor VIII expressed in mammalian cells. J. Biol. Chem. 263: 6352-6362.
    • (1988) J. Biol. Chem , vol.263 , pp. 6352-6362
    • Kaufman, R.J.1    Wasley, L.C.2    Dorner, A.J.3
  • 12
    • 0024597022 scopus 로고
    • Effect of von Willebrand factor coexpression on the synthesis and secretion of factor VIII in Chinese hamster ovary cells
    • Kaufman RJ, Wasley LC, Davies MV, Wise RJ, et al. (1989). Effect of von Willebrand factor coexpression on the synthesis and secretion of factor VIII in Chinese hamster ovary cells. Mol. Cell Biol. 9: 1233-1242.
    • (1989) Mol. Cell Biol , vol.9 , pp. 1233-1242
    • Kaufman, R.J.1    Wasley, L.C.2    Davies, M.V.3    Wise, R.J.4
  • 13
    • 34249677913 scopus 로고    scopus 로고
    • An efficient and safe herpes simplex virus type 1 amplicon vector for transcriptionally targeted therapy of human hepatocellular carcinomas
    • Lam PY, Sia KC, Khong JH, De Geest B, et al. (2007). An efficient and safe herpes simplex virus type 1 amplicon vector for transcriptionally targeted therapy of human hepatocellular carcinomas. Mol. Ther. 15: 1129-1136.
    • (2007) Mol. Ther , vol.15 , pp. 1129-1136
    • Lam, P.Y.1    Sia, K.C.2    Khong, J.H.3    De Geest, B.4
  • 16
    • 0029133142 scopus 로고
    • Novel forms of B-domain-deleted recombinant factor VIII molecules. Construction and biochemical characterization
    • Lind P, Larsson K, Spira J, Sydow-Backman M, et al. (1995). Novel forms of B-domain-deleted recombinant factor VIII molecules. Construction and biochemical characterization. Eur. J. Biochem. 232: 19-27.
    • (1995) Eur. J. Biochem , vol.232 , pp. 19-27
    • Lind, P.1    Larsson, K.2    Spira, J.3    Sydow-Backman, M.4
  • 17
    • 0029963548 scopus 로고    scopus 로고
    • Role of the liver-enriched transcription factor hepatocyte nuclear factor 1 in transcriptional regulation of the factor VIII gene
    • McGlynn LK, Mueller CR, Begbie M, Notley CR, et al. (1996). Role of the liver-enriched transcription factor hepatocyte nuclear factor 1 in transcriptional regulation of the factor VIII gene. Mol. Cell Biol. 16: 1936-1945.
    • (1996) Mol. Cell Biol , vol.16 , pp. 1936-1945
    • McGlynn, L.K.1    Mueller, C.R.2    Begbie, M.3    Notley, C.R.4
  • 18
    • 0025892211 scopus 로고
    • HNF-1 alpha and HNF-1 beta (vHNF-1) share dimerization and homeo domains, but not activation domains, and form heterodimers in vitro
    • Mendel DB, Hansen LP, Graves MK, Conley PB, et al. (1991). HNF-1 alpha and HNF-1 beta (vHNF-1) share dimerization and homeo domains, but not activation domains, and form heterodimers in vitro. Genes Dev. 5: 1042-1056.
    • (1991) Genes Dev , vol.5 , pp. 1042-1056
    • Mendel, D.B.1    Hansen, L.P.2    Graves, M.K.3    Conley, P.B.4
  • 19
    • 0023771077 scopus 로고
    • A new recombinant procoagulant protein derived from the cDNA encoding human factor VIII
    • Meulien P, Faure T, Mischler F, Harrer H, et al. (1988). A new recombinant procoagulant protein derived from the cDNA encoding human factor VIII. Protein Eng. 2: 301-306.
    • (1988) Protein Eng , vol.2 , pp. 301-306
    • Meulien, P.1    Faure, T.2    Mischler, F.3    Harrer, H.4
  • 20
    • 0037988905 scopus 로고    scopus 로고
    • Induction of immune tolerance to coagulation factor IX antigen by in vivo hepatic gene transfer
    • Mingozzi F, Liu YL, Dobrzynski E, Kaufhold A, et al. (2003). Induction of immune tolerance to coagulation factor IX antigen by in vivo hepatic gene transfer. J. Clin. Invest. 111: 1347-1356.
    • (2003) J. Clin. Invest , vol.111 , pp. 1347-1356
    • Mingozzi, F.1    Liu, Y.L.2    Dobrzynski, E.3    Kaufhold, A.4
  • 21
    • 0027361105 scopus 로고
    • Cell-specific expression of alpha 1-antitrypsin in human intestinal epithelium
    • Molmenti EP, Perlmutter DH and Rubin DC (1993). Cell-specific expression of alpha 1-antitrypsin in human intestinal epithelium. J. Clin. Invest. 92: 2022-2034.
    • (1993) J. Clin. Invest , vol.92 , pp. 2022-2034
    • Molmenti, E.P.1    Perlmutter, D.H.2    Rubin, D.C.3
  • 22
    • 11844252183 scopus 로고    scopus 로고
    • Hepatocyte-specific gene expression from integrated lentiviral vectors
    • Nash KL, Jamil B, Maguire AJ, Alexander GJ, et al. (2004). Hepatocyte-specific gene expression from integrated lentiviral vectors. J. Gene Med. 6: 974-983.
    • (2004) J. Gene Med , vol.6 , pp. 974-983
    • Nash, K.L.1    Jamil, B.2    Maguire, A.J.3    Alexander, G.J.4
  • 23
    • 0030008178 scopus 로고    scopus 로고
    • Liver-directed gene therapy: A retroviral vector with a complete LTR and the ApoE enhancer-alpha 1-antitrypsin promoter dramatically increases expression of human alpha 1-antitrypsin in vivo
    • Okuyama T, Huber RM, Bowling W, Pearline R, et al. (1996). Liver-directed gene therapy: a retroviral vector with a complete LTR and the ApoE enhancer-alpha 1-antitrypsin promoter dramatically increases expression of human alpha 1-antitrypsin in vivo. Hum. Gene Ther. 7: 637-645.
    • (1996) Hum. Gene Ther , vol.7 , pp. 637-645
    • Okuyama, T.1    Huber, R.M.2    Bowling, W.3    Pearline, R.4
  • 24
  • 25
    • 0027319588 scopus 로고
    • Biochemical, immunological, and in vivo functional characterization of B-domain-deleted factor VIII
    • Pittman DD, Alderman EM, Tomkinson KN, Wang JH, et al. (1993). Biochemical, immunological, and in vivo functional characterization of B-domain-deleted factor VIII. Blood 81: 2925-2935.
    • (1993) Blood , vol.81 , pp. 2925-2935
    • Pittman, D.D.1    Alderman, E.M.2    Tomkinson, K.N.3    Wang, J.H.4
  • 26
    • 0025775278 scopus 로고
    • vHNF1 is a homeoprotein that activates transcription and forms heterodimers with HNF1
    • Rey-Campos J, Chouard T, Yaniv M and Cereghini S (1991). vHNF1 is a homeoprotein that activates transcription and forms heterodimers with HNF1. EMBO J. 10: 1445-1457.
    • (1991) EMBO J , vol.10 , pp. 1445-1457
    • Rey-Campos, J.1    Chouard, T.2    Yaniv, M.3    Cereghini, S.4
  • 27
    • 0027471464 scopus 로고
    • A far-downstream hepatocyte-specific control region directs expression of the linked human apolipoprotein E and C-I genes in transgenic mice
    • Simonet WS, Bucay N, Lauer SJ and Taylor JM (1993). A far-downstream hepatocyte-specific control region directs expression of the linked human apolipoprotein E and C-I genes in transgenic mice. J. Biol. Chem. 268: 8221-8229.
    • (1993) J. Biol. Chem , vol.268 , pp. 8221-8229
    • Simonet, W.S.1    Bucay, N.2    Lauer, S.J.3    Taylor, J.M.4
  • 28
    • 0022411248 scopus 로고
    • Distribution of factor VIII mRNA and antigen in human liver and other tissues
    • Wion KL, Kelly D, Summerfield JA, Tuddenham EG, et al. (1985). Distribution of factor VIII mRNA and antigen in human liver and other tissues. Nature 317: 726-729.
    • (1985) Nature , vol.317 , pp. 726-729
    • Wion, K.L.1    Kelly, D.2    Summerfield, J.A.3    Tuddenham, E.G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.