In vivo monitoring of magnetically labelled mesenchymal stem cells administered intravascularly in rat acute renal failure

Swiss Medical Weekly

Volumn 138, Issue 27-28, 2008, Pages 404-412

  Sun, Jun Hui ^a,b   Teng, Gao Jun ^a   Zhang Long, Ma ^a   Ju, Sheng Hong ^a  

^a SOUTHEAST UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Acute renal failure; Animal model; Magnetic resonance imaging; Stem cells

Indexed keywords

CYCLINE;

ACUTE KIDNEY FAILURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL LABELING; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MESENCHYMAL STEM CELL; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PROTEIN EXPRESSION; RAT; STEM CELL TRANSPLANTATION; TRANSMISSION ELECTRON MICROSCOPY;

EID: 47949088295     PISSN: 14247860     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Ympa YP, Sakr Y, Reinhart K, Vincent JL. Has mortality from acute renal failure decreased? A systematic review of the literature. Am J Med. 2005;118:827-32.
2. Dai W, Hale SL, Martin BJ, Kuang JQ, Dow JS, Wold LE, et al. Allogeneic mesenchymal stem cell transplantation in postinfarcted rat myocardium: short- and long-term effects. Circulation. 2005;112:214-23.
3. Sato Y, Araki H, Kato J, Nakamura K, Kawano Y, Kobune M, et al. Human mesenchymal stem cells xenografted directly to rat liver are differentiated into human hepatocytes without fusion. Blood. 2005;106:756-63.
4. Herrera MB, Bussolati B, Bruno S, Fonsato V, Romanazzi GM, Camussi G. Mesenchymal stem cells contribute to the renal repair of acute tubular epithelial injury. Int J Mol Med. 2004;14:1035-41.
5. Togel F, Hu Z, Weiss K, Isaac J, Lange C, Westenfelder C. Administered mesenchymal stem cells protect against ischemic acute renal failure through differentiation-independent mechanisms. Am J Physiol Renal Physiol. 2005;289:F31-42.
6. Hoehn M, Kustermann E, Blunk J, Wiedermann D, Trapp T, Wecker S, et al. Monitoring of implanted stem cell migration in vivo: a highly resolved in vivo magnetic resonance imaging investigation of experimental stroke in rat. Proc Natl Acad Sci. USA 2002;99:16267-72.
7. Bos C, Delmas Y, Desmouliere A, Solanilla A, Hauger O, Grosset C, et al. In vivo MR imaging of intravascularly injected magnetically labelled mesenchymal stem cells in rat kidney and liver. Radiology. 2004;233:781-9.
8. Bulte JW, Zhang S, van Gelderen P, Herynek V, Jordan EK, Duncan ID, et al. Neuro transplantation of magnetically labelled oligodendrocyte progenitors: magnetic resonance tracking of cell migration and myelination. Proc Natl Acad Sci. U S A 1999;96:15256-61.
9. Kraitchman DL, Heldman AW, Atalar E, Amado LC, Martin BJ, Pittenger MF, et al. In vivo magnetic resonance imaging of mesenchymal stem cells in myocardial infarction. Circulation. 2003;107:2290-3.
10. Daldrup-Link HE, Rudelius M, Piontek G, Metz S, Brauer R, Debus G, et al. Migration of iron oxide-labelled human hematopoietic progenitor cells in a mouse model: in vivo monitoring with 1.5-T MR imaging equipment. Radiology. 2005;234:197-205.
11. Hauger O, Frost EE, van Heeswijk R, Deminiere C, Xue R, Delmas Y, et al. MR evaluation of the glomerular homing of magnetically labelled mesenchymal stem cells in a rat model of nephropathy. Radiology. 2006;238:200-10.
12. Pittenger MF, Mackay AM, Beck SC, Jaiswal RK, Douglas R, Mosca JD, et al. Multilineage potential of adult human mesenchymal stem cells. Science. 1999;284:143-7.
13. Ju SH, Teng GJ, Zhang Y, Ma M, Chen F, Ni YC. In vitro labelling and MR imaging of mesenchymal stem cells from human umbilical cord blood. Magn Reson Imaging. 2006;24:611-7.
14. Zager RA, Burkhart KM, Conrad DS and Gmur DJ. Iron, heme oxygenase, and glutathione: effects on myohemoglobinuric proximal tubular injury. Kidney Int. 1995;48:1624-34.
15. Wolff S, Balaban R. Assessing contrast on MR images. Radiology. 1997;202:25-9.
16. Chatterjee PK, Brown PA, Cuzzocrea S, Zacharowski K, Stewart KN, Mota-Filipe H, et al. Calpain inhibitor-1 reduces renal ischemia/reperfusion injury in the rat. Kidney Int. 2001;59:2073-83.
17. Zhou H, Kato A, Yasuda H, Miyaji T, Fujigaki Y, Yamamoto T, et al. The induction of cell cycle regulatory and DNA repair proteins in cisplatin-induced acute renal failure. Toxicol Appl Pharmacol. 2004;200:111-20.
18. Uchino S, Kellum JA, Bellomo R, Doig GS, Morimatsu H, Morgera S, et al. Acute renal failure in critically ill patients: a multinational, multicenter study. JAMA. 2005;294:813-8.
19. Imasawa T, Utsunomiya Y, Kawamura T, Zhong Y, Nagasawa R, Okabe M, et al. The potential of bone marrow-derived cells to differentiate to glomerular mesangial cells. J Am Soc Nephrol. 2001;12:1401-9.
20. Morigi M, Imberti B, Zoja C, Corna D, Tomasoni S, Abbate M, et al. Mesenchymal stem cells are renotropic, helping to repair the kidney and improve function in acute renal failure. J Am Soc Nephrol. 2004; 15:1794-804.
21. Lange C, Togel F, Ittrich H, Clayton F, Nolte-Ernsting C, Zander AR, et al. Administered mesenchymal stem cells enhance recovery from ischemia/reperfusion-induced acute renal failure in rats. Kindney Int. 2005;68:1613-7.
22. Hung SC, Deng WP, Yang WK, Liu RS, Lee CC, Su TC, et al. Mesenchymal stem cell targeting of microscopic tumors and tumor stroma development monitored by noninvasive in vivo positron emission tomography imaging. Clin Cancer Res. 2005;11:7749-56.
23. Shichinohe H, Kuroda S, Lee JB, Nishimura G, Yano S, Seki T, et al. In vivo tracking of bone marrow stromal cells transplanted into mice cerebral infarct by fluorescence optical imaging. Brain Res Brain Res Protoc. 2004;13:166-75.
24. Weissleder R. Molecular imaging: exploring the next frontier. Radiology. 1999;212:609-14.
25. Daldrup-Link HE, Rudelius M, Oostendorp RA, Settles M, Piontek G, Metz S, et al. Targeting of hematopoietic progenitor cells with MR contrast agents. Radiology. 2003;228:760-7.
26. Weissleder R, Stark DD, Engelstad BL, Bacon BR, Compton CC, White DL, et al. Superparamagetic iron oxide: pharmacokinetics and toxicity. AJR. 1989;152:167-73.