Synergy of aldosterone and high salt induces vascular smooth muscle hypertrophy through up-regulation of NOX1

Journal of Steroid Biochemistry and Molecular Biology

Volumn 111, Issue 1-2, 2008, Pages 29-36

  Fan, ChunYuan ^a   Kawai, Yasuyuki ^d   Inaba, Satoru ^a   Arakawa, Kenichiro ^a   Katsuyama, Masato ^c   Kajinami, Kouji ^d   Yasuda, Toshihiro ^b   Yabe Nishimura, Chihiro ^c   Konoshita, Tadashi ^a   Miyamori, Isamu ^a  

^a Third Department of Internal Medicine   (Japan)

^b UNIVERSITY OF FUKUI   (Japan)

^c KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^d KANAZAWA MEDICAL UNIVERSITY   (Japan)

Author keywords

Aldosterone; NOX1; Salt; Superoxide

Indexed keywords

ALDOSTERONE; EPLERENONE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; SODIUM CHLORIDE; SUPEROXIDE;

ANIMAL CELL; ARTICLE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVATION; GENE OVEREXPRESSION; MUSCLE HYPERTROPHY; NONHUMAN; RAT; SALT INTAKE; UPREGULATION; VASCULAR SMOOTH MUSCLE;

ALDOSTERONE; ANIMALS; AORTA; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; HYPERTROPHY; MUSCLE, SMOOTH, VASCULAR; NADH, NADPH OXIDOREDUCTASES; RATS; RNA, MESSENGER; SODIUM CHLORIDE, DIETARY; SUPEROXIDES; UP-REGULATION;

EID: 47849127408     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2008.02.012     Document Type: Article

References (46)

1. Fritsch Neves M., and Schiffrin E.L. Aldosterone: a risk factor for vascular disease. Curr. Hypertens. Rep. 5 (2003) 59-65
2. Ward M.R., Kanellakis P., Ramsey D., Funder J., and Bobik A. Eplerenone suppress constrictive remodeling and collagen accumulation after angioplasty in porcine coronary arteries. Circulation 104 4 (2001) 467-472
3. Rossi G.P., Di Bello V., Ganzaroli C., Sacchetto A., Cesari M., Bertini A., Giorgi D., Scognamiglio R., Mariani M., and Pessina A.C. Excess aldosterone is associated with alterations of myocardial texture in primary aldosteronism. Hypertension 40 (2002) 23-27
4. Rossi G.P., Sacchetto A., Visentin P., Canali C., Graniero G.R., Palatini P., and Pessina A.C. Changes in left ventricular anatomy and function in hypertension and primary aldosteronism. Hypertension 27 (1996) 1039-1045
5. Pitt B., Zannad F., Remme W., Cody R., Castaigne A., Perez A., Palensky J., and Wittes J. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. N. Engl. J. Med. 341 (1999) 709-717
6. Pitt B., Remme W., Zannad F., Neaton J., Martinez F., Roniker B., Bittman R., Hurley S., Kleiman J., and Gatlin M. Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction. N. Engl. J. Med. 348 (2003) 1309-1321
7. Oliver W.J., Cohen E.L., and Neel J.V. Blood pressure, sodium intake, and sodium related hormones in the Yanomamo Indians, a no-salt culture. Circulation 52 (1975) 146-151
8. Mancilha-Carvalho J.J., de Oliveria R., and Esposito R.J. Blood pressure and electrolyte excretion in the Yanomamo Indians, an isolated population. J. Human Hypertens. 3 (1989) 309-314
9. Conlin P.R. Interactions of high salt intake and the response of the cardiovascular system to aldosterone. Cardiol. Rev. 13 (2005) 118-124
10. Yoshida K., Kim-Mitsuyama S., Wake R., Izumiya Y., Izumi Y., Yukimura T., Ueda M., Yoshiyama M., and Iwao H. Excess aldosterone under normal salt diet induces cardiac hypertrophy and infiltration via oxidative stress. Hypertens. Res. 28 (2005) 447-455
11. Blasi E.R., Rocha R., Rudolph A.E., Blomme E.A., Polly M.L., and McMahon E.G. Aldosterone/salt induces renal inflammation and fibrosis in hypertensive rats. Kidney Int. 63 (2003) 1791-1800
12. Sun Y., Zhang J., Lu L., Chen S.S., Quinn M.T., and Weber K.T. Aldosterone-induced inflammation in rat heart. Role of oxidative stress. Am. J. Pathol. 161 (2002) 1773-1781
13. Nishiyama A., Yao L., Nagai Y., Miyata K., Yoshizumi M., Kagami S., Kondo S., Kiyomoto H., Shokoji T., Kimura S., Kohno M., and Abe Y. Possible contributions of reactive oxygen species and mitogen-activated protein kinase to renal injury in aldosterone/salt-induced hypertensive rats. Hypertension 43 (2004) 841-848
14. Virdis A., Neves M.F., Amiri F., Viel E., Touyz R.M., and Schiffrin E.L. Spironolactone improved angiotensin-induced vascular changes and oxidative stress. Hypertension 40 (2002) 504-510
15. Iglarz M., Touyz R.M., Viel E.C., Amiri F., and Schiffrin E.L. Involvement of oxidative stress in the profibrotic action of aldosterone. Interaction with the renin-angiotensin system. Am. J. Hypertens. 17 (2004) 597-603
16. Droge W. Free radicals in the physiological control of cell function. Physiol. Rev. 82 (2002) 47-95
17. Lassegue B., and Clempus R.E. Vascular NAD(P)H oxidases: specific features, expression, and regulation. Am. J. Physiol. 285 (2003) R277-R297
18. Griendling K.K., Sorescu D., and Ushio-Fukai M. NAD(P)H oxidase: role in cardiovascular biology and disease. Circ. Res. 86 (2000) 494-501
19. Hanna I.R., Taniyama Y., Szocs K., Rocic P., and Griendling K.K. NAD(P)H oxidase-derived reactive oxygen species as mediators of angiotensin II signaling. Antioxid. Redox. Signal. 4 (2002) 899-914
20. (2+)-activated NADPH oxidase in testis, spleen, and lymph nodes. J. Biol. Chem. 276 (2001) 37594-37601
21. Cheng G., Cao Z., Xu X., van Meir E.G., and Lambeth J.D. Homologs of gp91phox: cloning and tissue expression of Nox3, Nox4, and Nox5. Gene 269 (2001) 131-140
22. Lassegue B., Sorescu D., Szocs K., Yin Q., Akers M., Zhang Y., Grant S.L., Lambeth J.D., and Griendling K.K. Novel gp91(phox) homologues in vascular smooth muscle cells : nox1 mediates angiotensin II-induced superoxide formation and redox-sensitive signaling pathways. Circ. Res. 88 (2001) 888-894
23. Katsuyama M., Fan C., and Yabe-Nishimura C. NADPH oxidase is involved in prostaglandin F2alpha-induced hypertrophy of vascular smooth muscle cells: induction of NOX1 by PGF2alpha. J. Biol. Chem. 277 (2002) 13438-13442
24. phox is a critical component of the superoxide-generating NADH/NADPH oxidase system and regulates angiotensin II-induced hypertrophy in vascular smooth muscle cells. J. Biol. Chem. 271 (1996) 23317-23321
25. Koseki S., Tanabe T., Tani K., Asano S., Shioda T., Nagai Y., Shimada T., Ohkawa J., and Taira K. Factors governing the activity in vivo of ribozymes transcribed by RNA polymerase III. J. Virol. 73 (1999) 1868-1877
26. Kato Y., Kuwabara T., Warashina M., Toda H., and Taira K. Relationships between the activities in vitro and in vivo of various kinds of ribozyme and their intracellular localization in mammalian cells. J. Biol. Chem. 276 (2001) 15378-15385
27. Kuwabara T., Warashina M., Orita M., Koseki S., Ohkawa J., and Taira K. Formation of a catalytically active dimer by tRNA(Val)-driven short ribozymes. Nat. Biotechnol. 16 (1998) 961-965
28. Ago T., Kitazono T., Ooboshi H., Iyama T., Han Y.H., Takada J., Wakisaka M., Ibayashi S., Utsumi H., and Iida M. Nox4 as the major catalytic component of an endothelial NAD(P)H oxidase. Circulation 109 (2004) 227-233
29. phox in vascular smooth muscle. Am. J. Physiol. Heart Circ. Physiol. 288 (2005) H37-H42
30. Dikalova A., Clempus R., Lassegue B., Cheng G., McCoy J., Dikalov S., San Martin A., Lyle A., Weber D.S., Weiss D., Taylor W.R., Schmidt H.H., Owens G.K., Lambeth J.D., and Griendling K.K. Nox1 overexpression potentiates angiotensin II-induced hypertension and vascular smooth muscle hypertrophy in transgenic mice. Circulation 112 (2005) 2668-2676
31. Mukai K., Imai M., Shimada H., and Ishimura Y. Isolation and characterization of rat CYP11B genes involved in late steps of mineralo- and glucocorticoid syntheses. J. Biol. Chem. 268 (1994) 9130-9137
32. Gomez-Sanchez C.E., Zhou M.Y., Cozza E.N., Morita H., Foecking M.F., and Gomez-Sanchez E.P. Aldosterone biosynthesis in the rat brain. Endocrinology 138 (1997) 3369-3373
33. Silvestre J.S., Robert V., Heymes C., Aupetit-Faisant B., Mouas C., Moalic J.M., Swynghedauw B., and Delcayre C. Myocardial production of aldosterone and corticosterone in the rat: physiological regulation. J. Biol. Chem. 273 (1998) 4883-4891
34. Matsuno K., Yamada H., Iwata K., Jin D., Katsuyama M., Matsuki M., Takai S., Yamanishi K., Miyazaki M., Matsubara H., and Yabe-Nishimura C. Nox1 is involved in angiotensin II-mediated hypertension: a study in Nox1-deficient mice. Circulation 112 (2005) 2677-2685
35. Mangelsdorf D.J., Thummel C., Beato M., Herrlich P., Schutz G., Umesono K., Blumberg B., Kastner P., Mark M., Chambon P., and Evans R.M. The nuclear receptor superfamily: the second decade. Cell 83 (1995) 835-839
36. Christ M., Douwes K., Eisen C., Bechtner G., Theisen K., and Wehling M. Rapid effects of aldosterone on sodium transporter in vascular smooth muscle cells. Hypertension 25 (1995) 117-123
37. Liao D.F., Duff J.L., Daum G., Pelech S.L., and Berk B.C. Angiotensin II stimulates MAP kinase kinase kinase activity in vascular smooth muscle cells. Role Raf. Circ Res. 79 (1996) 1007-1014
38. Peiro C., Llergo J.L., Angulo J., Lopez-Novoa J.M., Rodriguez-Lopez A., Rodriguez-Manas L., and Sanchez-Ferrer C.F. Effects of captopril, losartan, and nifedipine on cell hypertrophy of cultured vascular smooth muscle from hypertensive Ren-2 transgenic rats. Br. J. Pharmacol. 121 (1997) 1438-1444
39. + exchanger in vascular smooth muscle cells by nongenomic and genomic mechanism. Kidney Int. 56 (1999) 1400-1412
40. Karmazyn M., Liu Q., Gan X.T., Brix B.J., and Fliegel L. Aldosterone increases NHE-1 expression and induces NHE-1-dependent hypertrophy in neonatal rat ventricular myocytes. Hypertension 42 (2003) 1171-1176
41. Yamamuro M., Yoshimura M., Nakayama M., Abe K., Shono M., Suzuki S., Sakamoto T., Saito Y., Nakao K., Yasue H., and Ogawa H. Direct effects of aldosterone on cardiomyocytes in the presence of normal and elevated extracellular sodium. Endocrinology 147 (2006) 1314-1321
42. 2+ exchanger type-1 in vascular smooth muscle. Nat. Med. 10 (2004) 1193-1199
43. Miyata K., Rahman M., Shokoji T., Nagai Y., Zhang G.X., Sun G.P., Kimura S., Yukimura T., Kiyomoto H., Kohno M., Abe Y., and Nishiyama A. Aldosterone stimulates reactive oxygen species production through activation of NADPH oxidase in rat mesangial cells. J. Am. Soc. Nephrol. 16 (2005) 2906-2912
44. Ushio-Fukai M., Griendling K.K., Becker P.L., Hilenski L., Halleran S., and Alexander R.W. Epidermal growth factor receptor transactivation by angiotensin II requires reactive oxygen species in vascular smooth muscle cells. Arterioscler. Thromb. Vasc. Biol. 21 (2001) 489-495
45. Bokemeyer D., Schmitz U., and Kramer H.J. Angiotensin II-induced growth of vascular smooth muscle cells requires an Src-dependent activation of the epidermal growth factor receptor. Kidney Int. 58 (2000) 549-558
46. Fan C.Y., Katsuyama M., and Yabe-Nishimura C. PKCδ mediates up-regulation of NOX1, a catalytic subunit of NADPH oxidase, via transactivation of the EGF receptor: possible involvement of PKCd in vascular hypertrophy. Biochem. J. 390 (2005) 761-767