Association between cough and cytology of bronchoalveolar lavage fluid and pulmonary function in horses diagnosed with inflammatory airway disease

Journal of Veterinary Internal Medicine

Volumn 22, Issue 4, 2008, Pages 1022-1028

  Bedenice, D ^a   Mazan, M R ^a   Hoffman, Andrew M ^a  

^a TUFTS UNIVERSITY   (United States)

Author keywords

Airway hyper responsiveness; Forced oscillation technique; Histamine challenge; Recurrent airway obstruction

Indexed keywords

ANIMAL; ANIMAL DISEASE; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; COUGHING; CYTOLOGY; FEMALE; HORSE; HORSE DISEASE; INFLAMMATION; LUNG FUNCTION TEST; LUNG LAVAGE; MALE; PATHOLOGY;

ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; COUGH; FEMALE; HORSE DISEASES; HORSES; INFLAMMATION; MALE; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RESPIRATORY FUNCTION TESTS;

EQUIDAE;

EID: 47849117128     PISSN: 08916640     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1939-1676.2008.0109.x     Document Type: Article

References (29)

1. Couëtil LL, Hoffman AM, Hodgson J, et al. Inflammatory airway disease of horses. J Vet Intern Med 2007;21:356-361.
2. Robinson NE, Berney C, Eberhart S, et al. Coughing, mucous accumulation, airway obstruction, and airway inflammation in control horses and horses affected with recurrent airway obstruction. Am J Vet Res 2003;64:550-557.
3. Hodgson DR, Christley RM, Wood JLN, et al. Relationship between coughing and airway inflammation in young race horses. In: Hoffman AM, Robinson NE, Wade JE, eds. Proceedings of a Workshop on Inflammatory Airway Disease: Defining the Syndrome, Monograph Series No. 9, Havemeyer Foundation. Suffolk, UK: R&W Publications (Newmarket) Limited; 2002:49-51.
4. Christley RM, Hodgson DR, Rose RJ, et al. Coughing in thoroughbred racehorses: Risk factors and tracheal endoscopic and cytological findings. Vet Rec 2001;148:99-104.
5. Sweeney CR, Humber KA, Roby KA. Cytologic findings of tracheobronchial aspirates from 66 Thoroughbred racehorses. Am J Vet Res 1992;53:1172-1175.
6. Derksen FJ, Brown CM, Sonea I, et al. Comparison of transtracheal aspirate and bronchoalveolar lavage cytology in 50 horses with chronic lung disease. Equine Vet J 1989;21:23-26.
7. Robinson DJ, Karmaus W, Holcombe SJ, et al. Airway inflammation in Michigan pleasure horses: Prevalence and risk factors. Equine Vet J 2006;38:293-299.
8. Holcombe SJ, Robinson NE, Derksen FJ, et al. Effect of tracheal mucous and tracheal cytology on racing performance in Thoroughbred race horses. Equine Vet J 2006;38:300-304.
9. Hoffman AM, Robinson NE, Wade JE. Proceedings of a Workshop on Inflammatory Airway Disease: Defining the Syndrome, Monograph Series No. 9, Havemeyer Foundation. Suffolk, UK: R&W Publications (Newmarket) Limited; 2002.
10. Hoffman AM, Mazan MR, Ellenberg S. Association between bronchoalveolar lavage cytologic features and airway reactivity in horses with a history of exercise intolerance. Am J Vet Res 1998;59:176-181.
11. Sanchez A, Couetil LL, Ward MP, et al. Effect of airway disease on blood gas exchange in racehorses. J Vet Intern Med 2005;19:87-92.
12. Couetil LL, Rosenthal FS, DeNicola DB, et al. Clinical signs, evaluation of bronchoalveolar lavage fluid, and assessment of pulmonary function in horses with inflammatory respiratory disease. Am J Vet Res 2001;62:538-546.
13. Couetil LL, Denicola DB. Blood gas, plasma lactate and bronchoalveolar lavage cytology analyses in racehorses with respiratory disease. Equine Vet J 1999;30(Suppl):77-82.
14. Hoffman AM, Mazan MR. Airway obstruction and hyper-reactivity in horse with signs of inflammatory airway disease. In: Hoffman AM, Robinson NE, Wade JE, eds. Proceedings of a Workshop on Inflammatory Airway Disease: Defining the Syndrome, Monograph Series No. 9, Havemeyer Foundation. Suffolk, UK: R&W Publications (Newmarket) Limited; 2002:71-74.
15. Hoffman A. Programme of lung function testing horses with suspected small airway disease. Equine Vet Educ 1999;11: 322-328.
16. Hoffman AM. Bronchoalveolar lavage technique and cytologic diagnosis of small airway inflammatory disease. Equine Vet Educ 1999;11:330-336.
17. Leclere M, Desnoyers M, Beauchamp G, et al. Comparison of four staining methods for detection of mast cells in equine bronchoalveolar lavage fluid. J Vet Intern Med 2006;20:377-381.
18. Hoffman AM. Clinical application of pulmonary function in the horse. In: Lekeux P, ed. International Veterinary Information Service (IVIS); Ithaca, NY: IVIS. 2002: B0304.0802.
19. Young SS, Hall LW. A rapid, non-invasive method for measuring total respiratory impedance in the horse. Equine Vet J 1989;21:99-105.
20. Young SS, Tesarowski D, Viel L. Frequency dependence of forced oscillatory respiratory mechanics in horses with heaves. J Appl Physiol 1997;82:983-987.
21. Mazan MR, Hoffman AM, Manjerovic N. Comparison of forced oscillation with the conventional method for histamine bronchoprovocation testing in horses. Am J Vet Res 1999;60: 174-180.
22. Viel L. Small airway disease as a vanguard for chronic obstructive pulmonary disease. Vet Clin North Am Equine Pract 1997;13:549-560.
23. Mazan M, Hoffman A. Inflammatory airway disease: Effect of athletic discipline. In: Hoffman A, Robinson NE, Wade JF, eds. Proceedings of a Workshop on Inflammatory Airway Disease: Defining the Syndrome, Monograph Series No. 9, Havemeyer Foundation. Suffolk, UK: R&W Publications (Newmarket) Limited; 2002:9-12.
24. Wood JLN, Newton JR, Chanter N, et al. A longitudinal epidemiological study of respiratory disease in racehorses: Disease definitions, prevalence and incidence. In: Wernery U, Wade J, Mumford J, et al. eds. Equine Infectious Diseases VIII. Suffolk, UK: R&W Publications (Newmarket) Limited; 1999:64-70.
25. Franchini M, Gill U, von Fellenberg R, et al. Interleukin-8 concentration and neutrophil chemotactic activity in bronchoalveolar lavage fluid of horses with chronic obstructive pulmonary disease following exposure to hay. Am J Vet Res 2000;61:1369-1374.
26. Barnes PJ. Neuroeffector mechanisms: The interface between inflammation and neuronal responses. J Allergy Clin Immunol 1996;98:S73-S81.
27. Gerber V, Robinson NE, Luethi S, et al. Airway inflammation and mucus in two age groups of asymptomatic well-performing sport horses. Equine Vet J 2003;35:491-495.
28. Fogarty U, Buckley T. Bronchoalveolar lavage findings in horses with exercise intolerance. Equine Vet J 1991;23:434-437.
29. Lutchen KR, Greenstein JL, Suki B. How inhomogeneities and airway walls affect frequency dependence and separation of airway and tissue properties. J Appl Physiol 1996;80:1696-1707.