메뉴 건너뛰기




Volumn 6, Issue 3, 2008, Pages 127-135

Advantages and limits of ADAMTS13 testing in thrombotic thrombocytopenic purpura

Author keywords

ADAMTS13; Thrombotic thrombocytopenic purpura; TTP

Indexed keywords

NEUTRALIZING ANTIBODY; VON WILLEBRAND FACTOR CLEAVING PROTEINASE;

EID: 47749132284     PISSN: 17232007     EISSN: None     Source Type: Journal    
DOI: 10.2450/2008.0056-07     Document Type: Review
Times cited : (38)

References (46)
  • 1
    • 0037379399 scopus 로고    scopus 로고
    • Advances in the pathogenesis, diagnosis, and treatment of thrombotic thrombocytopenic purpura
    • Tsai HM. Advances in the pathogenesis, diagnosis, and treatment of thrombotic thrombocytopenic purpura. J Am Soc Nephrol 2003; 14: 1072-81.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 1072-1081
    • Tsai, H.M.1
  • 4
    • 0002978048 scopus 로고
    • Hyaline thrombosis of the terminal arterioles and capillaries: A hitherto undescribed disease
    • Moschcowitz E. Hyaline thrombosis of the terminal arterioles and capillaries: a hitherto undescribed disease. Proc NY Pathol Soc 1924; 24: 21-4.
    • (1924) Proc NY Pathol Soc , vol.24 , pp. 21-24
    • Moschcowitz, E.1
  • 5
    • 84936619463 scopus 로고
    • Thrombotic thrombocytopenic purpura: Report of 16 cases and review of the literature
    • Amorosi EL, Ultmann JE. Thrombotic thrombocytopenic purpura: report of 16 cases and review of the literature. Medicine (Baltimore) 1966; 45: 139-59.
    • (1966) Medicine (Baltimore) , vol.45 , pp. 139-159
    • Amorosi, E.L.1    Ultmann, J.E.2
  • 6
    • 0026048114 scopus 로고
    • Comparison of plasma exchange with plasma infusion in the treatment of thrombotic thrombocytopenic purpura. Canadian Apheresis Study Group
    • Rock GA, Shumak KH, Buskard NA, et al. Comparison of plasma exchange with plasma infusion in the treatment of thrombotic thrombocytopenic purpura. Canadian Apheresis Study Group. N Engl J Med 1991; 325: 393-7.
    • (1991) N Engl J Med , vol.325 , pp. 393-397
    • Rock, G.A.1    Shumak, K.H.2    Buskard, N.A.3
  • 7
    • 0020428664 scopus 로고
    • Unusually large plasma factor VIII: Von Willebrand factor multimers in chronic relapsing thrombotic thrombocytopenic purpura
    • Moake JL, Rudy CK, Troll JH, et al. Unusually large plasma factor VIII: von Willebrand factor multimers in chronic relapsing thrombotic thrombocytopenic purpura. N Engl J Med 1982; 307: 1432-5.
    • (1982) N Engl J Med , vol.307 , pp. 1432-1435
    • Moake, J.L.1    Rudy, C.K.2    Troll, J.H.3
  • 8
    • 0032569884 scopus 로고    scopus 로고
    • von Willebrand factor cleaving protease in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome
    • Furlan M, Robles R, Galbusera M, et al. von Willebrand factor cleaving protease in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome. N Engl J Med 1998; 339: 1578-84.
    • (1998) N Engl J Med , vol.339 , pp. 1578-1584
    • Furlan, M.1    Robles, R.2    Galbusera, M.3
  • 9
    • 0032569840 scopus 로고    scopus 로고
    • Antibodies to von Willebrand factor cleaving protease in acute thrombotic thrombocytopenic purpura
    • Tsai HM, Lian EC. Antibodies to von Willebrand factor cleaving protease in acute thrombotic thrombocytopenic purpura. N Engl J Med 1998; 339: 1585-94.
    • (1998) N Engl J Med , vol.339 , pp. 1585-1594
    • Tsai, H.M.1    Lian, E.C.2
  • 10
    • 0035798582 scopus 로고    scopus 로고
    • Structure of von Willebrand factor-cleaving protease (ADAMTS13), a metalloprotease involved in thrombotic thrombocytopenic purpura
    • Zheng X, Chung D, Takayama TK, et al. Structure of von Willebrand factor-cleaving protease (ADAMTS13), a metalloprotease involved in thrombotic thrombocytopenic purpura. J Biol Chem 2001; 276: 41059-63.
    • (2001) J Biol Chem , vol.276 , pp. 41059-41063
    • Zheng, X.1    Chung, D.2    Takayama, T.K.3
  • 11
    • 7044225940 scopus 로고    scopus 로고
    • Molecular mechanisms in thrombotic thrombovytopenic purpura
    • Tsai HM. Molecular mechanisms in thrombotic thrombovytopenic purpura. Semin Thromb Hemost 2004; 30: 549-56.
    • (2004) Semin Thromb Hemost , vol.30 , pp. 549-556
    • Tsai, H.M.1
  • 12
    • 72849154313 scopus 로고
    • Studies on thrombopoeisis. A factor in normal human plasma required for platelet production; chronic thrombocytopenia due to its deficiency
    • Schulman I, Pierce M, Lukens A, et al. Studies on thrombopoeisis. A factor in normal human plasma required for platelet production; chronic thrombocytopenia due to its deficiency. Blood 1960; 16: 943-57.
    • (1960) Blood , vol.16 , pp. 943-957
    • Schulman, I.1    Pierce, M.2    Lukens, A.3
  • 13
    • 0018098453 scopus 로고
    • Congenital deficiency of a factor in normal plasma that reverses microangiopathic hemolysis and thrombocytopenia
    • Upshaw JD. Congenital deficiency of a factor in normal plasma that reverses microangiopathic hemolysis and thrombocytopenia. N Engl J Med 1978; 298: 1350-2.
    • (1978) N Engl J Med , vol.298 , pp. 1350-1352
    • Upshaw, J.D.1
  • 14
    • 0035807348 scopus 로고    scopus 로고
    • Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura
    • Levy GG, Nichols WC, Lian EC, et al. Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura. Nature 2001; 413: 488-94.
    • (2001) Nature , vol.413 , pp. 488-494
    • Levy, G.G.1    Nichols, W.C.2    Lian, E.C.3
  • 15
    • 2942588403 scopus 로고    scopus 로고
    • Epitope mapping of ADAMTS13 autoantibodies in acquired thrombotic thrombocytopenic purpura
    • Klaus C, Plaimauer B, Studt JD, et al. Epitope mapping of ADAMTS13 autoantibodies in acquired thrombotic thrombocytopenic purpura. Blood 2004; 103: 4514-9.
    • (2004) Blood , vol.103 , pp. 4514-4519
    • Klaus, C.1    Plaimauer, B.2    Studt, J.D.3
  • 16
    • 0142183462 scopus 로고    scopus 로고
    • Nonneutralizing IgM and IgG antibodies to von Willebrand factor-cleaving protease (ADAMTS-13) in a patient with thrombotic thrombocytopenic purpura
    • Scheiflinger F, Knöbl P, Trattner B, et al. Nonneutralizing IgM and IgG antibodies to von Willebrand factor-cleaving protease (ADAMTS-13) in a patient with thrombotic thrombocytopenic purpura. Blood 2003; 102: 3241-3.
    • (2003) Blood , vol.102 , pp. 3241-3243
    • Scheiflinger, F.1    Knöbl, P.2    Trattner, B.3
  • 17
    • 23744486523 scopus 로고    scopus 로고
    • ADAMTS13 autoantibodies in patients with thrombotic microangiopathies and other immunomediated diseases
    • Rieger M, Mannucci PM, Hovinga JA, et al. ADAMTS13 autoantibodies in patients with thrombotic microangiopathies and other immunomediated diseases. Blood 2005; 106: 1262-7.
    • (2005) Blood , vol.106 , pp. 1262-1267
    • Rieger, M.1    Mannucci, P.M.2    Hovinga, J.A.3
  • 18
    • 0033151555 scopus 로고    scopus 로고
    • Von Willebrand factor proteolysis is deficient in classic but not in bone marrow transplantation- associated, thrombotic thrombocytopenic purpura
    • van der Plas RM, Schiphorst ME, Huizinga EG, et al. Von Willebrand factor proteolysis is deficient in classic but not in bone marrow transplantation- associated, thrombotic thrombocytopenic purpura. Blood 1999; 93: 3798-802.
    • (1999) Blood , vol.93 , pp. 3798-3802
    • van der Plas, R.M.1    Schiphorst, M.E.2    Huizinga, E.G.3
  • 19
    • 32944456736 scopus 로고    scopus 로고
    • Current concepts in thrombotic thrombocytopenic purpura
    • Tsai HM. Current concepts in thrombotic thrombocytopenic purpura. Annu Rev Med 2006; 57: 419-36.
    • (2006) Annu Rev Med , vol.57 , pp. 419-436
    • Tsai, H.M.1
  • 20
    • 0036236255 scopus 로고    scopus 로고
    • Assays of von Willebrand factor-cleaving protease: A test for diagnosis of familial and acquired thrombotic thrombocytopenic purpura
    • Furlan M, Lammle B. Assays of von Willebrand factor-cleaving protease: a test for diagnosis of familial and acquired thrombotic thrombocytopenic purpura. Semin Thromb Hemost 2002; 28: 167-72.
    • (2002) Semin Thromb Hemost , vol.28 , pp. 167-172
    • Furlan, M.1    Lammle, B.2
  • 21
    • 0347986766 scopus 로고    scopus 로고
    • Assays of ADAMTS-13 activity
    • Veyradier A, Girma JP. Assays of ADAMTS-13 activity. Semin Hematol 2004; 41: 41-7.
    • (2004) Semin Hematol , vol.41 , pp. 41-47
    • Veyradier, A.1    Girma, J.P.2
  • 22
    • 30344479161 scopus 로고    scopus 로고
    • Molecular biology of ADAMTS13 and diagnostic utility of ADAMTS13 proteolytic activity and inhibitor assays
    • Shelat S, Ai J, Zheng XL. Molecular biology of ADAMTS13 and diagnostic utility of ADAMTS13 proteolytic activity and inhibitor assays. Semin Thromb Hemost 2005; 31: 659-72.
    • (2005) Semin Thromb Hemost , vol.31 , pp. 659-672
    • Shelat, S.1    Ai, J.2    Zheng, X.L.3
  • 23
    • 17144408687 scopus 로고    scopus 로고
    • FRETS-VWF73, a fluorogenic substrate for ADAMTS13 assay
    • Kokame K, Nobe Y, Kokubo Y, et al. FRETS-VWF73, a fluorogenic substrate for ADAMTS13 assay. Br J Haemost 2005; 129: 93-100.
    • (2005) Br J Haemost , vol.129 , pp. 93-100
    • Kokame, K.1    Nobe, Y.2    Kokubo, Y.3
  • 24
    • 33645968978 scopus 로고    scopus 로고
    • FRETS-VWF73: A rapid and predictive tool for thrombotic thrombocytopenic purpura
    • Groot E, Hulstein JJ, Rison CN, et al. FRETS-VWF73: a rapid and predictive tool for thrombotic thrombocytopenic purpura. J Thromb Haemost 2006; 4: 698-9.
    • (2006) J Thromb Haemost , vol.4 , pp. 698-699
    • Groot, E.1    Hulstein, J.J.2    Rison, C.N.3
  • 25
    • 24644513413 scopus 로고    scopus 로고
    • Measurement of ADAMTS13 activity and inhibitors
    • Miyata T, Kokame K, Banno F. Measurement of ADAMTS13 activity and inhibitors. Curr Opin Hematol 2005; 12: 384-9.
    • (2005) Curr Opin Hematol , vol.12 , pp. 384-389
    • Miyata, T.1    Kokame, K.2    Banno, F.3
  • 26
    • 0043203072 scopus 로고    scopus 로고
    • Measurement of von Willebrand factor-cleaving protease (ADAMTS-13) activity in plasma: A multicenter comparison of different assay methods
    • Studt JD, Bohm M, Budde U, et al. Measurement of von Willebrand factor-cleaving protease (ADAMTS-13) activity in plasma: a multicenter comparison of different assay methods. J Thromb Haemost 2003; 1: 1882-7.
    • (2003) J Thromb Haemost , vol.1 , pp. 1882-1887
    • Studt, J.D.1    Bohm, M.2    Budde, U.3
  • 27
    • 0036893186 scopus 로고    scopus 로고
    • ADAMTS-13 rapidly cleaves newly secreted ultralarge von Willebrand factor multimers on the endothelial surface under flowing conditions
    • Dong JF, Moake JL, Nolasco L, et al. ADAMTS-13 rapidly cleaves newly secreted ultralarge von Willebrand factor multimers on the endothelial surface under flowing conditions. Blood 2002; 100: 4033-9.
    • (2002) Blood , vol.100 , pp. 4033-4039
    • Dong, J.F.1    Moake, J.L.2    Nolasco, L.3
  • 28
    • 34447309717 scopus 로고    scopus 로고
    • ADAMTS13 activity to antigen ratio in physiological and pathological conditions associated with an increased risk of thrombosis
    • Feys HB, Canciani MT, Peyvandi F, et al. ADAMTS13 activity to antigen ratio in physiological and pathological conditions associated with an increased risk of thrombosis. Br J Haematol 2007; 138: 534-40.
    • (2007) Br J Haematol , vol.138 , pp. 534-540
    • Feys, H.B.1    Canciani, M.T.2    Peyvandi, F.3
  • 29
    • 0035885927 scopus 로고    scopus 로고
    • Specific von Willebrand factor-cleaving protease in thrombotic microangiopathies: A study of 111 cases
    • Veyradier A, Obert B, Houllier A, et al. Specific von Willebrand factor-cleaving protease in thrombotic microangiopathies: a study of 111 cases. Blood 2001; 98: 1765-72.
    • (2001) Blood , vol.98 , pp. 1765-1772
    • Veyradier, A.1    Obert, B.2    Houllier, A.3
  • 30
    • 19044365367 scopus 로고    scopus 로고
    • Predicting response to plasma exchange in patients with thrombotic thrombocytopenic purpura with measurement of vWF-cleaving protease activity
    • Mori Y, Wada H, Gabazza EC, et al. Predicting response to plasma exchange in patients with thrombotic thrombocytopenic purpura with measurement of vWF-cleaving protease activity. Transfusion 2002; 42: 572-80.
    • (2002) Transfusion , vol.42 , pp. 572-580
    • Mori, Y.1    Wada, H.2    Gabazza, E.C.3
  • 31
    • 0037968640 scopus 로고    scopus 로고
    • ADAMTS13 activity in thrombotic thrombocytopenic purpurahemolytic uremic syndrome: Relation to presenting features and clinical outcomes in a prospective cohort of 142 patients
    • Vesely SK, George JN, Lammle B, et al. ADAMTS13 activity in thrombotic thrombocytopenic purpurahemolytic uremic syndrome: relation to presenting features and clinical outcomes in a prospective cohort of 142 patients. Blood 2003; 102: 60-8.
    • (2003) Blood , vol.102 , pp. 60-68
    • Vesely, S.K.1    George, J.N.2    Lammle, B.3
  • 32
    • 3242705780 scopus 로고    scopus 로고
    • Reseau d'Etude des Microangiopathies Thrombotiques de l'Adulte. Severe ADAMTS13 deficiency in adult idiopathic thrombotic microangiopathies defines a subset of patients characterized by various autoimmune manifestations, lower platelet count, and mild renal involvement
    • Coppo P, Bengoufa D, Veyradier A, et al; Reseau d'Etude des Microangiopathies Thrombotiques de l'Adulte. Severe ADAMTS13 deficiency in adult idiopathic thrombotic microangiopathies defines a subset of patients characterized by various autoimmune manifestations, lower platelet count, and mild renal involvement. Medicine (Baltimore) 2004; 83: 233-44.
    • (2004) Medicine (Baltimore) , vol.83 , pp. 233-244
    • Coppo, P.1    Bengoufa, D.2    Veyradier, A.3
  • 33
    • 8844286829 scopus 로고    scopus 로고
    • von Willebrand factor cleaving protease (ADAMTS-13) and ADAMTS-13 neutralizing autoantibodies in 100 patients with thrombotic thrombocytopenic purpura
    • Peyvandi F, Ferrari S, Lavoretano S, et al. von Willebrand factor cleaving protease (ADAMTS-13) and ADAMTS-13 neutralizing autoantibodies in 100 patients with thrombotic thrombocytopenic purpura. Br J Haematol 2004; 127: 433-9.
    • (2004) Br J Haematol , vol.127 , pp. 433-439
    • Peyvandi, F.1    Ferrari, S.2    Lavoretano, S.3
  • 34
    • 2542490269 scopus 로고    scopus 로고
    • Effect of plasma exchange on plasma ADAMTS13 metalloprotease activity, inhibitor level, and clinical outcome in patients with idiopathic and nonidiopathic thrombotic thrombocytopenic purpura
    • Zheng XL, Kaufman RM, Goodnough LT, et al. Effect of plasma exchange on plasma ADAMTS13 metalloprotease activity, inhibitor level, and clinical outcome in patients with idiopathic and nonidiopathic thrombotic thrombocytopenic purpura. Blood 2004; 103: 4043-9.
    • (2004) Blood , vol.103 , pp. 4043-4049
    • Zheng, X.L.1    Kaufman, R.M.2    Goodnough, L.T.3
  • 35
    • 0037100531 scopus 로고    scopus 로고
    • Von Willebrand factor-cleaving protease (ADAMTS13) in thrombocytopenic disorders: A severely deficient activity is specific for thrombotic thrombocytopenic purpura
    • Bianchi V, Robles R, Alberio L, et al. Von Willebrand factor-cleaving protease (ADAMTS13) in thrombocytopenic disorders: a severely deficient activity is specific for thrombotic thrombocytopenic purpura. Blood 2002; 100: 710-3.
    • (2002) Blood , vol.100 , pp. 710-713
    • Bianchi, V.1    Robles, R.2    Alberio, L.3
  • 36
    • 0346095392 scopus 로고    scopus 로고
    • von Willebrand factor-cleaving protease (ADAMTS-13) activity determination in the diagnosis of thrombotic microangiopathies: The Swiss experience
    • Hovinga JA, Studt JD, Alberio L, et al. von Willebrand factor-cleaving protease (ADAMTS-13) activity determination in the diagnosis of thrombotic microangiopathies: the Swiss experience. Semin Hematol 2004; 41: 75-82.
    • (2004) Semin Hematol , vol.41 , pp. 75-82
    • Hovinga, J.A.1    Studt, J.D.2    Alberio, L.3
  • 37
    • 33745435227 scopus 로고    scopus 로고
    • Thrombotic microangiopathy with acquired deficiency in ADAMTS 13 activity in lung transplant recipients
    • Mal H, Veyradier A, Brugiere O, et al. Thrombotic microangiopathy with acquired deficiency in ADAMTS 13 activity in lung transplant recipients. Transplantation 2006; 81: 1628-32.
    • (2006) Transplantation , vol.81 , pp. 1628-1632
    • Mal, H.1    Veyradier, A.2    Brugiere, O.3
  • 38
    • 0037089066 scopus 로고    scopus 로고
    • Cancer-related thrombotic microangiopathy secondary to von Willebrand factor-cleaving protease deficiency
    • Blot E, Decaudin D, Veyradier A, et al. Cancer-related thrombotic microangiopathy secondary to von Willebrand factor-cleaving protease deficiency. Thromb Res 2002; 106: 127-30.
    • (2002) Thromb Res , vol.106 , pp. 127-130
    • Blot, E.1    Decaudin, D.2    Veyradier, A.3
  • 39
    • 0141832540 scopus 로고    scopus 로고
    • Is severe deficiency of ADAMTS-13 specific for thrombotic thrombocytopenic purpura? Yes
    • Tsai HM. Is severe deficiency of ADAMTS-13 specific for thrombotic thrombocytopenic purpura? Yes. J Thromb Haemost 2003; 1: 625-31.
    • (2003) J Thromb Haemost , vol.1 , pp. 625-631
    • Tsai, H.M.1
  • 40
    • 1242344743 scopus 로고    scopus 로고
    • Severe deficiency of VWF-cleaving protease (ADAMTS13) activity defines a distinct population of thrombotic microangiopathy patients
    • Raife T, Atkinson B, Montgomery R, et al. Severe deficiency of VWF-cleaving protease (ADAMTS13) activity defines a distinct population of thrombotic microangiopathy patients. Transfusion 2004; 44: 146-50.
    • (2004) Transfusion , vol.44 , pp. 146-150
    • Raife, T.1    Atkinson, B.2    Montgomery, R.3
  • 41
    • 33644795851 scopus 로고    scopus 로고
    • Reseau d'Etude des Microangiopathies Thrombotiques de l'Adulte. Prognostic value of inhibitory anti-ADAMTS13 antibodies in adult-acquired thrombotic thrombocytopenic purpura
    • Coppo P, Wolf M, Veyradier A, et al; Reseau d'Etude des Microangiopathies Thrombotiques de l'Adulte. Prognostic value of inhibitory anti-ADAMTS13 antibodies in adult-acquired thrombotic thrombocytopenic purpura. Br J Haematol 2005; 132: 66-74.
    • (2005) Br J Haematol , vol.132 , pp. 66-74
    • Coppo, P.1    Wolf, M.2    Veyradier, A.3
  • 42
    • 20444500957 scopus 로고    scopus 로고
    • The course of ADAMTS-13 activity and inhibitor titre in the treatment of thrombotic thrombocytopenic purpura with plasma exchange and vincristine
    • Böhm M, Betz C, Miesbach W, et al. The course of ADAMTS-13 activity and inhibitor titre in the treatment of thrombotic thrombocytopenic purpura with plasma exchange and vincristine. Br J Haematol 2005; 129: 644-52.
    • (2005) Br J Haematol , vol.129 , pp. 644-652
    • Böhm, M.1    Betz, C.2    Miesbach, W.3
  • 43
    • 0033791481 scopus 로고    scopus 로고
    • High titers of inhibitors of von Willebrand factor-cleaving metalloproteinase in a fatal case of acute thrombotic thrombocytopenic purpura
    • Tsai HM. High titers of inhibitors of von Willebrand factor-cleaving metalloproteinase in a fatal case of acute thrombotic thrombocytopenic purpura. Am J Hematol 2000; 65: 251-5.
    • (2000) Am J Hematol , vol.65 , pp. 251-255
    • Tsai, H.M.1
  • 44
    • 30344433272 scopus 로고    scopus 로고
    • Relapse of thrombotic thrombocytopenic purpura: Is it a continuum of disease?
    • Willis MS, Bandarenko N. Relapse of thrombotic thrombocytopenic purpura: is it a continuum of disease? Semin Thromb Hemost 2005; 31: 700-8.
    • (2005) Semin Thromb Hemost , vol.31 , pp. 700-708
    • Willis, M.S.1    Bandarenko, N.2
  • 45
    • 33947594746 scopus 로고    scopus 로고
    • French Clinical and Biological Network on Adult Thrombotic Microangiopathies. Prognostic value of anti-ADAMTS 13 antibody features (Ig isotype, titer, and inhibitory effect) in a cohort of 35 adult French patients undergoing a first episode of thrombotic microangiopathy with undetectable ADAMTS 13 activity
    • Ferrari S, Scheiflinger F, Rieger M, et al; French Clinical and Biological Network on Adult Thrombotic Microangiopathies. Prognostic value of anti-ADAMTS 13 antibody features (Ig isotype, titer, and inhibitory effect) in a cohort of 35 adult French patients undergoing a first episode of thrombotic microangiopathy with undetectable ADAMTS 13 activity. Blood 2007; 109: 2815-22.
    • (2007) Blood , vol.109 , pp. 2815-2822
    • Ferrari, S.1    Scheiflinger, F.2    Rieger, M.3
  • 46
    • 40849114959 scopus 로고    scopus 로고
    • ADAMTS13 and anti-ADAMTS13 antibodies as markers for recurrence of acquired thrombotic thrombocytopenic purpura during remission
    • Peyvandi F, Lavoretano S, Palla R, et al. ADAMTS13 and anti-ADAMTS13 antibodies as markers for recurrence of acquired thrombotic thrombocytopenic purpura during remission. Haematologica 2008; 2: 232-9.
    • (2008) Haematologica , vol.2 , pp. 232-239
    • Peyvandi, F.1    Lavoretano, S.2    Palla, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.