Hair analysis of anabolic steroids in connection with doping control - Results from horse samples

Journal of Mass Spectrometry

Volumn 43, Issue 7, 2008, Pages 1001-1008

  Anielski, P ^a  

^a Institute of Doping Analysis and Sports Biochemistry   (Germany)

Author keywords

Anabolic steroids; Doping control; Hair analysis; Horse; Long term detection; Testosterone propionate

Indexed keywords

BODY FLUIDS; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; DRUG PRODUCTS; ESTERS; HEALTH; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIPIDS; MASS SPECTROMETERS; MASS SPECTROMETRY; MOBILE TELECOMMUNICATION SYSTEMS; ORGANIC COMPOUNDS; SPECTROMETERS; SPECTROMETRY; SPECTRUM ANALYSIS;

ANABOLIC STEROIDS; ANALYTICAL RESULTS; CONTROL SAMPLES; DOPING CONTROL; HAIR ANALYSIS; HIGH RESOLUTION MASS SPECTROMETRY (HRMS); LIMITS OF DETECTION (LOD); NANDROLONE; SAMPLE PREPARATIONS; TANDEM MASS SPECTROMETRY (MS/MS); TESTOSTERONE (T); TESTOSTERONE PROPIONATE; TRIMETHYLSILYL (TMS); URINE ANALYSIS; URINE SAMPLES;

GAS CHROMATOGRAPHY;

ANABOLIC AGENT; NANDROLONE; NANDROLONE DECANOATE; NANDROLONE LAURATE; NANDROLONE PHENPROPIONATE; TESTOSTERONE; TESTOSTERONE CIPIONATE; TESTOSTERONE PHENYLPROPIONATE; TESTOSTERONE PROPIONATE; TESTOSTERONE UNDECANOATE; TRIMETHYLSILYL DERIVATIVE;

ARTICLE; CONTROLLED STUDY; DOPING; DRUG DETERMINATION; GAS CHROMATOGRAPHY; HAIR ANALYSIS; HORMONE DETERMINATION; HORSE; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY;

ANABOLIC AGENTS; ANIMALS; DOPING IN SPORTS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HAIR; HORSES; MALE; REPRODUCIBILITY OF RESULTS; SUBSTANCE ABUSE DETECTION; TANDEM MASS SPECTROMETRY; TESTOSTERONE PROPIONATE; URINALYSIS;

EQUIDAE;

EID: 47749119179     PISSN: 10765174     EISSN: 10969888     Source Type: Journal    
DOI: 10.1002/jms.1446     Document Type: Article

References (33)

1. World Anti-Doping Agency. The 2008 prohibited list - international standard, 2007; 1.
2. Thieme D, Grosse J, Sachs H, Mueller R. Analytical strategy for detecting doping agents in hair. Forensic Science International 2000; 107: 335.
3. Rivier L. Is there a place for hair analysis in doping controls? Forensic Science International 2000; 107: 309.
4. Midio A, de Moraes Moreau R, Silva O. The possibilities of hair analysis in the determination of involuntary doping in sports. Sports Medicine 2001; 31: 321.
5. Kintz P, Villain M, Cirimele V. Hair analysis for drug detection. Therapeutic Drug Monitoring 2006; 28: 442.
6. Gambelunghe C, Sommavilla M, Ferranti C, Rossi R, Aroni K, Manes N, Bacci M. Analysis of anabolic steroids in hair by GC/MS/MS. Biomedical Chromatography 2007; 21: 369.
7. Gaillard Y, Vayssette F, Pepin G. Compared interest between hair analysis and urinalysis in doping controls. Results for amphetamines, corticosteroids and anabolic steroids in racing cyclists. Forensic Science International 2000; 107: 361.
8. Dumestre-Toulet V, Cirimele V, Ludes B, Gromb S, Kintz P. Hair analysis of seven bodybuilders for anabolic steroids, ephedrine, and clenbuterol. Journal of Forensic Sciences 2002; 47: 211.
9. Kintz P. Testing for anabolic steroids in hair: a review. Legal Medicine (Tokyo, Japan) 2003; 5(suppl1): S29.
10. Anielski P, Thieme D, Schlupp A, Grosse J, Ellendorff F, Mueller RK. Detection of testosterone, nandrolone and precursors in horse hair. Analytical and Bioanalytical Chemistry 2005; 383: 903.
11. Hold KM, Borges CR, Wilkins DG, Rollins DE, Joseph RE Jr. Detection of nandrolone, testosterone, and their esters in rat and human hair samples. Journal of Analytical Toxicology 1999; 23: 416.
12. Segura J, Pichini S, Peng S, de la Torre X. Hair analysis and detectability of single dose administration of androgenic steroid esters. Forensic Science International 2000; 107: 347.
13. Nielen M, Lasaroms J, Mulder P, Van Hende J, van Rhijn J, Groot M. Multi residue screening of intact testosterone esters and boldenone undecylenate in bovine hair using liquid chromatography electrospray tandem mass spectrometry. Journal of Chromatography B 2006; 830: 126.
14. Boyer S, Garcia P, Popot M, Steiner V, Lesieur M. Detection of testosterone propionate administration in horse hair samples. Journal of Chromatography B 2007; 852: 684.
15. Thieme D, Grosse J, Sachs H, Mueller RK. Detection of several anabolic steroids of abuse in human hair. 16th Cologne workshop on dope analysis. Recent Advances in Doping Analysis 1998; 6: 9.
16. Kintz P, Cirimele V, Jeanneau T, Ludes B. Identification of testosterone and testosterone esters in human hair. Journal of Analytical Toxicology 1999; 23: 352.
17. Gaillard Y, Vayssette F, Balland A, Pepin G. Gas chromatographic-tandem mass spectrometric determination of anabolic steroids and their esters in hair. Application in doping control and meat quality control. Journal of Chromatography B 1999; 735: 189.
18. Balikova M. Hair analysis for drugs of abuse. Plausibility of interpretation. Biomedical Papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 2005; 149: 199.
19. Pragst F, Balikova M. State of the art in hair analysis for detection of drug and alcohol abuse. Clinica Chimica Acta 2006; 370: 17.
20. Gratacós-Cubarsí M, Castellari M, Valero A, García-Regueiro J. Hair analysis for veterinary drug monitoring in livestock production. Journal of Chromatography B 2006; 834: 14.
21. Fédération Equestre Internationale. Equine prohibited list - veterinary regulations, 2006; 31.
22. Junkmann K. Long-acting steroids in reproduction. Recent Progress in Hormone Research 1957; 13: 389.
23. Nieschlag E, Cüppers HJ, Wiegelmann W, Wickings EJ. Bioavailability and LH-suppressing effect of different testosterone preparations in normal and hypogonadal men. Hormone Research 1976; 7: 138.
24. van der Vies J. Pharmacokinetics of anabolic steroids. Wien Med Wochenschr 1993; 143: 366.
25. Cirimele V, Kintz P, Mangin P. Drug concentrations in human hair after bleaching. Journal of Analytical Toxicology 1995; 19: 331.
26. Jurado C, Kintz P, Menéndez M, Repetto M. Influence of the cosmetic treatment of hair on drug testing. International Journal of Legal Medicine 1997; 110: 159.
27. Henderson G. Mechanisms of drug incorporation into hair. Forensic Science International 1993; 63: 19.
28. Nakahara Y, Takahashi K, Kikura R. Hair analysis for drugs of abuse. X. Effect of physicochemical properties of drugs on the incorporation rates into hair. Biological and Pharmaceutical Bulletin 1995; 18: 1223.
29. Deng X, Kurosu A, Pounder D. Detection of anabolic steroids in head hair. Journal of Forensic Sciences 1999; 44: 343.
30. Kintz P, Cirimele V, Sachs H, Jeanneau T, Ludes B. Testing for anabolic steroids in hair from two bodybuilders. Forensic Science International 1999; 101: 209.
31. Popot M, Boyer S, Maciejewski P, Garcia P, Dehennin L, Bonnaire Y. Approaches to the detection of drugs in horse hair. Proceedings of the 13th International Conference of Racing Analysts and Veterinarians, Cambridge, 2000; 115.
32. Schlupp A, Anielski P, Thieme D, Mueller R, Meyer H, Ellendorff F. The beta-agonist clenbuterol in mane and tail hair of horses. Equine Veterinary Journal 2004; 36: 118.
33. Dunnett M, Lees P. Hair analysis as a novel investigative tool for the detection of historical drug use/misuse in the horse: a pilot study. Equine Veterinary Journal 2004; 36: 113.