Synthesis of an oligodeoxyribonucleotide adduct of mitomycin C by the postoligomerization method via a triamino mitosene

Journal of the American Chemical Society

Volumn 130, Issue 29, 2008, Pages 9556-9565

  Champeil, Elise ^b   Paz, Manuel M ^c   Ladwa, Sweta ^d   Clement, Cristina C ^e   Zatorski, Andrzej ^f   Tomasz, Maria ^a  

^a CITY UNIVERSITY OF NEW YORK   (United States)

^b JOHN JAY COLLEGE OF CRIMINAL JUSTICE   (United States)

^c UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^d A2SP Ltd   (United Kingdom)

^e ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^f CITIGROUP   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; GENES; NUCLEIC ACIDS; OLIGONUCLEOTIDES; ORGANIC ACIDS; RAW MATERIALS; SEMICONDUCTOR COUNTERS; SYNTHESIS (CHEMICAL);

CHEMOTHERAPEUTIC AGENTS; DEOXYGUANOSINE (DG); DNA ADDUCTS; IN-VITRO; IN-VIVO; MITOMYCIN-C (MMC); MONO-ADDUCTS; NATURAL PRODUCTS; OLIGO NUCLEOTIDES; SITE SPECIFIC;

COMPLEXATION;

2 FLUORO O 6 (2 TRIMETHYLSILYLETHYL)DEOXYINOSINE; 2,7 DIAMINO 10 DECARBAMOYLMITOSENE; MITOMYCIN C DERIVATIVE; N 2 PHENYLACETYL; NATURAL PRODUCT; OLIGODEOXYNUCLEOTIDE; OLIGONUCLEOTIDE; PENICILLIN AMIDASE; TRIAMINOMITOSENE; ZINC BROMIDE;

ARTICLE; DNA ADDUCT; DNA SYNTHESIS; DRUG CONFORMATION; ELUTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; OLIGOMERIZATION; PROTON NUCLEAR MAGNETIC RESONANCE; REDUCTION; STRUCTURE ACTIVITY RELATION;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CIRCULAR DICHROISM; DNA ADDUCTS; INOSINE; MITOMYCIN; MITOMYCINS; NUCLEOSIDES; OLIGODEOXYRIBONUCLEOTIDES; SPECTROPHOTOMETRY, ULTRAVIOLET; TANDEM MASS SPECTROMETRY; TRIMETHYLSILYL COMPOUNDS;

EID: 47749118027     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja802118p     Document Type: Article

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