Allele-specific targeting of hsa-miR-657 to human IGF2R creates a potential mechanism underlying the association of ACAA-insertion/deletion polymorphism with type 2 diabetes

Biochemical and Biophysical Research Communications

Volumn 374, Issue 1, 2008, Pages 101-105

  Lv, Ke ^a   Guo, Yingjun ^a   Zhang, Yiliang ^a   Wang, Kaiyu ^a   Jia, Yin ^a   Sun, Shuhan ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

3 untranslated region; DNA sequence polymorphism; Insulin like growth factor 2 receptor; microRNAs; Translational regulation; Type 2 diabetes

Indexed keywords

LUCIFERASE; MICRORNA; SOMATOMEDIN B RECEPTOR;

3' UNTRANSLATED REGION; ARTICLE; BINDING SITE; CELL STRAIN HEK293; CELL STRAIN HEPG2; CONTROLLED STUDY; DNA SEQUENCE; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE DELETION; GENE INSERTION; GENETIC POLYMORPHISM; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; REPORTER GENE; RNA DEGRADATION; TRANSLATION REGULATION;

3' UNTRANSLATED REGIONS; ALLELES; BINDING SITES; CELL LINE; COMPUTATIONAL BIOLOGY; DIABETES MELLITUS, TYPE 2; GENE EXPRESSION REGULATION; HUMANS; MICRORNAS; MUTAGENESIS, INSERTIONAL; POLYMORPHISM, GENETIC; RECEPTOR, IGF TYPE 2; SEQUENCE DELETION;

EID: 47749103305     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.06.102     Document Type: Article

References (26)

1. Bartel D.P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116 (2004) 281-297
2. Calin G.A., Liu C.G., Sevignani C., Ferracin M., Felli N., Dumitru C.D., Shimizu M., Cimmino A., Zupo S., Dono M., Dell'Aquila M.L., Alder H., Rassenti L., Kipps T.J., Bullrich F., Negrini M., and Croce C.M. MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias. Proc. Natl. Acad. Sci. USA 101 (2004) 11755-11760
3. Care A., Catalucci D., Felicetti F., Bonci D., Addario A., Gallo P., Bang M.L., Segnalini P., Gu Y., Dalton N.D., Elia L., Latronico M.V., Hoydal M., Autore C., Russo M.A., Dorn II G.W., Ellingsen O., Ruiz-Lozano P., Peterson K.L., Croce C.M., Peschle C., and Condorelli G. MicroRNA-133 controls cardiac hypertrophy. Nat. Med. 13 (2007) 613-618
4. Yang B., Lin H., Xiao J., Lu Y., Luo X., Li B., Zhang Y., Xu C., Bai Y., Wang H., Chen G., and Wang Z. The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2. Nat. Med. 13 (2007) 486-491
5. Lewis B.P., Burge C.B., and Bartel D.P. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120 (2005) 15-20
6. Krek A., Grun D., Poy M.N., Wolf R., Rosenberg L., Epstein E.J., MacMenamin P., da Piedade I., Gunsalus K.C., Stoffel M., and Rajewsky N. Combinatorial microRNA target predictions. Nat. Genet. 37 (2005) 495-500
7. Georges M., Coppieters W., and Charlier C. Polymorphic miRNA-mediated gene regulation: contribution to phenotypic variation and disease. Curr. Opin. Genet. Dev. 17 (2007) 166-176
8. Abelson J.F., Kwan K.Y., O'Roak B.J., Baek D.Y., Stillman A.A., Morgan T.M., Mathews C.A., Pauls D.L., Rasin M.R., Gunel M., Davis N.R., Ercan-Sencicek A.G., Guez D.H., Spertus J.A., Leckman J.F., Dure L.S.T., Kurlan R., Singer H.S., Gilbert D.L., Farhi A., Louvi A., Lifton R.P., Sestan N., and State M.W. Sequence variants in SLITRK1 are associated with Tourette's syndrome. Science 310 (2005) 317-320
9. Clop A., Marcq F., Takeda H., Pirottin D., Tordoir X., Bibe B., Bouix J., Caiment F., Elsen J.M., Eychenne F., Larzul C., Laville E., Meish F., Milenkovic D., Tobin J., Charlier C., and Georges M. A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep. Nat. Genet. 38 (2006) 813-818
10. Mishra P.J., Humeniuk R., Mishra P.J., Longo-Sorbello G.S., Banerjee D., and Bertino J.R. A miR-24 microRNA binding-site polymorphism in dihydrofolate reductase gene leads to methotrexate resistance. Proc. Natl. Acad. Sci. USA 104 (2007) 13513-13518
11. van Haeften T.W., and Twickler T.B. Insulin-like growth factors and pancreas β cells. Eur. J. Clin. Invest. 34 (2004) 249-255
12. Di Bacco A., and Gill G. The secreted glycoprotein CREG inhibits cell growth dependent on the mannose-6-phosphate/insulin-like growth factor II receptor. Oncogene 22 (2003) 5436-5445
13. Ikushima H., Munakata Y., Ishii T., Iwata S., Terashima M., Tanaka H., Schlossman S.F., and Morimoto C. Internalization of CD26 by mannose 6-phosphate/insulin-like growth factor II receptor contributes to T cell activation. Proc. Natl. Acad. Sci. USA 97 (2000) 8439-8444
14. Gasanov U., Koina C., Beagley K.W., Aitken R.J., and Hansbro P.M. Identification of the insulin-like growth factor II receptor as a novel receptor for binding and invasion by Listeria monocytogenes. Infect. Immun. 74 (2006) 566-577
15. Duggirala R., Blangero J., Almasy L., Arya R., Dyer T.D., Williams K.L., Leach R.J., O'Connell P., and Stern M.P. A major locus for fasting insulin concentrations and insulin resistance on chromosome 6q with strong pleiotropic effects on obesity-related phenotypes in nondiabetic Mexican Americans. Am. J. Hum. Genet. 68 (2001) 1149-1164
16. Villuendas G., Botella-Carretero J.I., Lopez-Bermejo A., Gubern C., Ricart W., Fernandez-Real J.M., San Millan J.L., and Escobar-Morreale H.F. The ACAA-insertion/deletion polymorphism at the 3'UTR of the IGF-II receptor gene is associated with type 2 diabetes and surrogate markers of insulin resistance. Eur. J. Endocrinol. 155 (2006) 331-336
17. Costello M., Baxter R.C., and Scott C.D. Regulation of soluble insulin-like growth factor II/mannose 6-phosphate receptor in human serum: measurement by enzyme-linked immunosorbent assay. J. Clin. Endocrinol. Metab. 84 (1999) 611-617
18. Rusinov V., Baev V., Minkov I.N., and Tabler M. MicroInspector: a web tool for detection of miRNA binding sites in an RNA sequence. Nucleic Acids Res. 33 (2005) W696-W700
19. John B., Enright A.J., Aravin A., Tuschl T., Sander C., and Marks D.S. Human microRNA targets. PLoS Biol. 2 (2004) e363
20. Griffiths-Jones S., Grocock R.J., van Dongen S., Bateman A., and Enright A.J. miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 34 (2006) D140-D144
21. Landi D., Gemignani F., Barale R., and Landi S. A catalog of polymorphisms falling in microRNA-binding regions of cancer genes. DNA Cell Biol. (2007)
22. Morgan D.O., Edman J.C., Standring D.N., Fried V.A., Smith M.C., Roth R.A., and Rutter W.J. Insulin-like growth factor II receptor as a multifunctional binding protein. Nature 329 (1987) 301-307
23. Martin M.M., Buckenberger J.A., Jiang J., Malana G.E., Nuovo G.J., Chotani M., Feldman D.S., Schmittgen T.D., and Elton T.S. The human angiotensin II type 1 receptor +1166 A/C polymorphism attenuates microrna-155 binding. J. Biol. Chem. 282 (2007) 24262-24269
24. Martin M.M., Lee E.J., Buckenberger J.A., Schmittgen T.D., and Elton T.S. MicroRNA-155 regulates human angiotensin II type 1 receptor expression in fibroblasts. J. Biol. Chem. 281 (2006) 18277-18284
25. Young L.E., Fernandes K., McEvoy T.G., Butterwith S.C., Gutierrez C.G., Carolan C., Broadbent P.J., Robinson J.J., Wilmut I., and Sinclair K.D. Epigenetic change in IGF2R is associated with fetal overgrowth after sheep embryo culture. Nat. Genet. 27 (2001) 153-154
26. Gicquel C., Weiss J., Amiel J., Gaston V., Le Bouc Y., and Scott C.D. Epigenetic abnormalities of the mannose-6-phosphate/IGF2 receptor gene are uncommon in human overgrowth syndromes. J. Med. Genet. 41 (2004) e4