Cardioprotective Effects of Nicorandil in Patients Undergoing On-Pump Coronary Artery Bypass Surgery

Journal of Cardiothoracic and Vascular Anesthesia

Volumn 22, Issue 4, 2008, Pages 548-553

  Yamamoto, Shinichi ^a   Yamada, Tatsuya ^a   Kotake, Yoshifumi ^a   Takeda, Junzo ^a  

^a KEIO UNIVERSITY   (Japan)

Author keywords

cardioprotective effect; coronary artery bypass graft surgery; nicorandil

Indexed keywords

CREATINE KINASE MB; DIAZEPAM; DILTIAZEM; DOBUTAMINE; FENTANYL; GLYCERYL TRINITRATE; MIDAZOLAM; NICORANDIL; PETHIDINE; PROPOFOL; RANITIDINE; SODIUM CHLORIDE; TROPONIN T; VECURONIUM;

ADULT; AGED; ANESTHESIA; ARTERIAL BLOOD; ARTICLE; BLOOD SAMPLING; CARDIOPULMONARY BYPASS; CLINICAL ARTICLE; CLINICAL TRIAL; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; ELECTIVE SURGERY; FEMALE; HEART PROTECTION; HUMAN; LOADING DRUG DOSE; MALE; OFF PUMP CORONARY SURGERY; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; UNIVERSITY HOSPITAL;

AGED; CARDIOTONIC AGENTS; CARDIOVASCULAR DISEASES; CORONARY ARTERY BYPASS; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MALE; MIDDLE AGED; NICORANDIL; POSTOPERATIVE COMPLICATIONS; PROSPECTIVE STUDIES;

EID: 47749101683     PISSN: 10530770     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.jvca.2008.02.011     Document Type: Article

References (32)

1. Murry C.E., Jennings R.B., and Reimer K.A. Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation 74 (1986) 1124-1136
2. Ishihara M., Sato H., Tateishi H., et al. Implications of prodromal angina pectoris in anterior wall acute myocardial infarction: Acute angiographic findings and long-term prognosis. J Am Coll Cardiol 30 (1997) 970-975
3. Wu Z., Iivainen T., Pehkonen E., et al. Ischemic preconditioning suppressed ventricular tachyarrhythmias after myocardial revascularization. Circulation 106 (2002) 3091-3096
4. Gross G.J., and Auchampach J.A. Blockade of ATP-sensitive potassium cannels prevents myocardial preconditioning in dogs. Circ Res 70 (1992) 223-233
5. 1 receptors. Circulation 86 (1992) 1310-1316
6. Auchampach J.A., Grover G.J., and Gross G.J. Blockade of ischaemic preconditioning in dogs by the novel ATP-dependent potassium channel antagonist sodium 5-hydroxydecanoate. Cardiovasc Res 26 (1992) 1054-1062
7. ATP channels and myocardial preconditioning: An update. Am J Physol Heart Circ Physiol 285 (2003) 921-930
8. Sato T., Sasaki N., O'ourke B., et al. Nicorandil, a potent cardioprotective agent, acts by opening mitochondrial ATP-dependent potassium channels. J Am Coll Cardiol 35 (2000) 514-518
9. IONA Study Group. Effect of nicorandil on coronary events in patients with stable angina: The Impact Of Nicorandil in Angina (IONA) randomized trial. Lancet 359 (2002) 1269-1275
10. ATP channel in unstable angina. Eur Heart J 20 (1999) 51-57
11. Kawamura T., Kadosaki M., Nara N., et al. Nicorandil attenuates NF-κB activation, adhesion molecule expression, and cytokine production in patients with coronary artery bypass surgery. Shock 24 (2005) 103-108
12. Ito I., Hayashi Y., Kawai Y., et al. Prophylactic effect of intravenous nicorandil on perioperative myocardial damage in patients undergoing off-pump coronary artery bypass surgery. J Cardiovasc Pharmacol 44 (2004) 501-506
13. Hayashi Y., Sawa Y., Ohtake S., et al. Controlled nicorandil administration for myocardial protection during coronary artery bypass grafting under cardiopulmonary bypass. J Cardiovasc Pharmacol 38 (2001) 21-28
14. Kaneko T., Saito Y., Hikawa Y., et al. Dose-dependent prophylactic effect of nicorandil, an ATP-sensitive potassium channel opener, on intraoperative myocardial ischaemia in patients undergoing major abdominal surgery. Br J Anaesth 86 (2001) 332-337
15. Chinnan N.K., Puri G.D., and Thingnam S.K.S. Myocardial protection by nicorandil during open-heart surgery under cardioprotective bypass. Eur J Anesth 24 (2007) 26-32
16. Kersten J.R., Schmeling T.J., Pagel P.S., et al. Isoflurane mimics ischemic preconditioning via activation of KATP channels: Reduction of myocardial infarct size in rabbit. Anesthesiology 87 (1997) 361-370
17. Kehl F., Pagel P.S., Krolikowski J.G., et al. Isoflurane does not produce a second window of preconditioning against myocardial infarction in vivo. Anesth Analg 95 (2002) 1162-1168
18. Bolli R., Bhatti Z.A., Tang X.-L., et al. Evidence that late preconditioning against myocardial stunning in conscious rabbits is triggered by the generation of nitric oxide. Circ Res 81 (1997) 1094-1107
19. Banerjee S., Tang X.-L., Qiu Y., et al. Nitroglycerin induces late preconditioning against myocardial stunning via a PKC-dependent pathway. Am J Physiol 277 (1999) 2488-2494
20. Kashimoto S., Makoto S., Ishiguro T., et al. Nicorandil decreases cardiac events during and after noncardiac surgery. J Clin Anesth 19 (2007) 44-48
21. Agbo-Godeau S., Joly P., Lauret P., et al. Association of major aphthous ulcers and nicorandil. Lancet 352 (1998) 1598-1599
22. Watson A., Al Ozairi O., Fraser A., et al. Nicorandil-associated anal ulceration. Lancet 360 (2002) 546-547
23. Healy C.M., Smyth Y., and Flint S.R. Persistent nicorandil-induced oral ulceration. Heart 90 (2004) e38
24. Hackel D.B., Reimer K.A., and Ideker R.E. Comparison of enzymatic and anatomic estimates of infarct size in man. Circulation 70 (1984) 824-835
25. Katus A.H., Remppis A., Neumann F.J., et al. Diagnostic efficiency of troponin T measurements in acute myocardial infarction. Circulation 83 (1991) 902-912
26. The Joint European Society of Cardiology/American College of Cardiology Committee. Myocardial infarction redefined-A consensus document of the Joint European Society of Cardiology/American College of Cardiology Committee for the redefinition of myocardial infarction. J Am Coll Cardiol 36 (2000) 959-969
27. Adams III J.E., Abendschein D.R., and Jaffe A.S. Biochemical markers of myocardial injury. Is MB creatine kinase the choice for the 1990s?. Circulation 88 (1993) 750-763
28. Chan M.Y., and Pronovost P.J. Clinical utility of biomarkers in myocardial injury. Curr Opin Anaesthesiol 17 (2004) 49-55
29. Ohtani T., Ueda Y., Shimizu M., et al. Association between cardiac troponin T elevation and angioscopic morphology of culprit lesion in patients with non-ST-segment elevation acute coronary syndrome. Am Heart J 150 (2005) 227-233
30. Wu Z., Pehkonen E., Laurikka J., et al. Protective effect of unstable angina in coronary artery bypass surgery. Scand Cardiovasc J 34 (2000) 486-492
31. Benoit M., Paris M., Silleran J., et al. Cardiac troponin I: Its contribution to the diagnosis of perioperative myocardial infarction and various complications of cardiac surgery. Crit Care Med 29 (2001) 1880-1886
32. Januzzi Jr. J.L., Lewandrowski K., MacGillivray T.E., et al. A comparison of cardiac troponin T and creatine kinase-MB for patient evaluation after cardiac surgery. J Am Coll Cardiol 39 (2002) 1518-1523