Bone metabolism in pregnant women exposed to single compared with multiple courses of corticosteroids

Obstetrics and Gynecology

Volumn 111, Issue 6, 2008, Pages 1352-1358

  Vidaeff, Alex C ^a,b   Carroll, Mary A ^c   Mele, Lisa ^c   Wapner, Ronald J ^c   Mercer, Brian ^c   Peaceman, Alan M ^c   Sorokin, Yoram ^c   Dudley, Donald J ^c   Spong, Catherine Y ^c   Leveno, Kenneth J ^c   Harper, Margaret ^c   Caritis, Steve N ^c   Miodovnik, Menachem ^c   Thorp, John M ^c   Moawad, Atef ^c   O'Sullivan, Mary J ^c   Carpenter, Marshall W ^c   Rouse, Dwight J ^c   Sibai, Baha ^c  

^a UNIVERSITY OF TEXAS   (United States)

^b UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

BETAMETHASONE; CARBOXY TERMINAL TELOPEPTIDE; COLLAGEN TYPE 1; PLACEBO; BIOLOGICAL MARKER; COLLAGEN TYPE I TRIMERIC CROSS LINKED PEPTIDE; COLLAGEN TYPE I TRIMERIC CROSS-LINKED PEPTIDE; GLUCOCORTICOID; PEPTIDE; PEPTIDE FRAGMENT; PROCOLLAGEN; PROCOLLAGEN TYPE I CARBOXY TERMINAL PEPTIDE;

ARTICLE; BLOOD SAMPLING; BONE METABOLISM; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORTICOSTEROID THERAPY; DRUG EXPOSURE; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MULTICENTER STUDY; OSSIFICATION; OSTEOLYSIS; PREGNANT WOMAN; PRENATAL PERIOD; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; BLOOD; BONE; COMPARATIVE STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; METABOLISM; PREGNANCY; PREMATURE LABOR;

BETAMETHASONE; BIOLOGICAL MARKERS; BONE AND BONES; COLLAGEN TYPE I; DOUBLE-BLIND METHOD; FEMALE; GLUCOCORTICOIDS; HUMANS; OBSTETRIC LABOR, PREMATURE; PEPTIDE FRAGMENTS; PEPTIDES; PREGNANCY; PROCOLLAGEN;

EID: 47749087521     PISSN: 00297844     EISSN: None     Source Type: Journal    
DOI: 10.1097/AOG.0b013e318173573b     Document Type: Article

References (30)

1. Wapner RJ, Sorokin Y, Thorn EA, Johnson F, Dudley DJ, Spong CY, et al. Single versus weekly courses of antenatal corticosteroids: Evaluation of safety and efficacy. Am J Obstet Gynecol 2006;195:633-42.
2. National Institutes of Health Consensus Development Panel. Antenatal corticosteroids revisited: repeat courses - National Institutes of Health Consensus Development Conference Statement, August 17-18, 2000. Obstet Gynecol 2001;98:144-50.
3. Effect of corticosteroids for fetal maturation on perinatal outcomes. NIH Consensus Development Panel on the Effect of Corticosteroids for Fetal Maturation on Perinatal Outcomes. JAMA 1995;273:413-8.
4. Liggins GC, Howie RN. A controlled trial of antepartum glucocorticoid treatment for prevention of the respiratory distress syndrome in premature infants. Pediatrics 1972;50: 515-25.
5. Ballard PL, Ballard RA. Scientific basis and therapeutic regimens for use of antenatal glucocorticoids. Am J Obstet Gynecol 1995;173:254-62.
6. Murphy K, Aghajafari F. Single versus repetitive courses of corticosteroids: what do we know? Clin Obstet Gynecol 2003; 46:161-73.
7. Brocklehurst P, Gates S, McKenzie-McHarg K, Alfirevic Z, Chamberlain G. Are we prescribing multiple courses of antenatal corticosteroids? A survey of practice in the UK. Br J Obstet Gynaecol 1999;106:977-9.
8. Spencer C, Pakarian F. Are we prescribing multiple courses of antenatal corticosteroids? A survey of practice in the UK. Br J Obstet Gynaecol 2000;107:434-5.
9. O'Connell MP. Are we prescribing multiple courses of antenatal corticosteroids? A survey of practice in the UK. Br J Obstet Gynaecol 2000;107:577-8.
10. Sinha A. Are we prescribing multiple courses of antenatal corticosteroids? A survey of practice in the UK. Br J Obstet Gynaecol 2000; 107:578.
11. Guinn DA, Atkinson MW, Sullivan L, Lee M, MacGregor S, Parilla BV, et al. Single vs. weekly courses of antenatal corticosteroids for women at risk of preterm delivery: a randomized controlled trial. JAMA 2001;286:1581-7.
12. Crowley P, Chalmers I, Keirse MJ. The effects of corticosteroid administration before preterm delivery: an overview of the evidence from controlled trials. Br J Obstet Gynaecol 1990;97: 11-25.
13. Effect of antenatal dexamethasone administration on the prevention of respiratory distress syndrome. AmJ Obstet Gynecol 1981;141:276-87.
14. Aghajafari F, Murphy K, Willan A, Ohlsson A, Amankwah K, Matthews S, et al. Multiple courses of antenatal corticosteroids: A systematic review and meta-analysis. AmJ Obstet Gynecol 2001;185:1073-80.
15. Ogueh O, Khastgir G, Studd JW, Jones J, Alaghband-Zadeh J, Johnson MR. Antenatal corticosteroid therapy and risk of osteoporosis. Br J Obstet Gynaecol 1998;105:551-5.
16. Ogueh O, Khastgir G, Studd JW, King H, Johnson MR. Postpartum bone mineral density following antenatal dexamethasone therapy. Br J Obstet Gynaecol 1999;106:1093-5.
17. Eriksen EF, Charles P, Melsen F, Mosekilde L, Risteli L, Risteli J. Serum markers of type I collagen formation and degradation in metabolic bone disease: correlation with bone histomor-phometry. J Bone Miner Res 1993;8:127-32.
18. Melkko J, Niemi S, Risteli L, Risteli J. Radioimmunoassay of the carboxyterminal propeptide of human type I procollagen. Clin Chem 1990;36:1328-32.
19. Risteli J, Elomaa I, Niemi S, Novamo A, Risteli L. Radioimmunoassay for the pyridinoline cross-linked carboxyterminal telopeptide of type I collagen: a new serum marker of bone collagen degradation. Clin Chem 1993;39:635-40.
20. Christenson RH. Biochemical markers of bone metabolism: an overview. Clin Biochem 1997;30:573-93.
21. Khastgir G, Studd JW, King H, Abdalla H, Jones J, Carter G, et al. Changes in bone density and biochemical markers of bone turnover in pregnancy-associated osteoporosis. Br J Obstet Gynaecol 1996;103:716-8.
22. Kovacs CS, Kronenberg HM. Maternal-fetal calcium and bone metabolism during pregnancy, puerperium, and lactation. Endocr Rev 1997;18:832-72.
23. Naylor KE, Iqbal P, Fledelius C, Fraser RB, Eastell R. The effect of pregnancy on bone mineral density and bone turnover. J Bone Miner Res 2000;15:129-37.
24. Cross NA, Hillman LS, Allen SH, Krause GF, Vieira NE. Calcium homeostasis and bone metabolism during pregnancy, lactation, and postweaning: a longitudinal study. Am J Clin Nutr 1995;61:514-23.
25. Yamaga A, Taga M, Minaguchi H, Sato K. Changes in bone mass as determined by ultrasound and biochemical markers of bone turnover during pregnancy and puerperium: a longitudinal study. J Clin Endocrinol Metab 1996;81:752-6.
26. More C, Bhattoa HP, Bettembuk P, Balogh A. The effects of pregnancy and lactation on hormonal status and biochemical markers of bone turnover. Eur J Obstet Gynecol Reprod Biol 2003;106:209-13.
27. Namgung R, Tsang R. Bone in the pregnant mother and newborn at birth. Clin Chim Acta 2003;333:1-11.
28. Puistola U, Risteli L, Kauppila A, Knip M, Risteli J. Markers of type I and type III collagen synthesis in serum as indicators of tissue growth during pregnancy. J Clin Endocrinol Metab 1993;77:178-82.
29. Sowers M, Crutchfield M, Jannausch M, Updike S, Corton G. A prospective evaluation of bone mineral change in pregnancy. Obstet Gynecol 1991;77:841-5.
30. Baylink DJ. Glucocorticoid-induced osteoporosis. N Engl J Med 1983;309:306-8.