Rapid iron loading in a pregnant woman with transfusion-dependent thalassemia after brief cessation of iron chelation therapy

European Journal of Haematology

Volumn 81, Issue 2, 2008, Pages 157-159

  Farmaki, Kallistheni ^a   Gotsis, Efstathios ^b   Tzoumari, Ioanna ^a   Berdoukas, Vasilios ^a  

^a General Hospital of Corinth   (Greece)

^b Euromedica Enkephalos   (Greece)

Author keywords

Chelation therapy; Pregnancy; Thalassemia major; Transfusion iron load

Indexed keywords

DEFERIPRONE; DEFEROXAMINE;

ADULT; ARTICLE; BLOOD TRANSFUSION; BREAST FEEDING; CASE REPORT; CHELATION THERAPY; DRY WEIGHT; FEMALE; FERRITIN BLOOD LEVEL; FERTILIZATION IN VITRO; GLUCOSE METABOLISM; HEART LEFT VENTRICLE EJECTION FRACTION; HUMAN; IRON CHELATION; IRON OVERLOAD; LABORATORY DIAGNOSIS; LIVER WEIGHT; NUCLEAR MAGNETIC RESONANCE IMAGING; PREGNANCY COMPLICATION; PREGNANT WOMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SPLENECTOMY; THALASSEMIA MAJOR; THYROID FUNCTION; TREATMENT DURATION; TREATMENT WITHDRAWAL;

ADULT; BLOOD TRANSFUSION; CHELATION THERAPY; FEMALE; FERRITINS; HUMANS; IRON; IRON CHELATING AGENTS; IRON OVERLOAD; LIVER; PREGNANCY; THALASSEMIA; WITHHOLDING TREATMENT;

EID: 47649108424     PISSN: 09024441     EISSN: 16000609     Source Type: Journal    
DOI: 10.1111/j.1600-0609.2008.01092.x     Document Type: Article

References (8)

1. Jensen CE, Tuck SM, Wonke B. Fertility in beta thalassaemia major: a report of 16 pregnancies, preconceptual evaluation and a review of the literature. Br J Obstet Gynaecol 1995 102 : 625 9.
2. Skordis N, Christou S, Koliou M, Pavlides N, Angastiniotis M. Fertility in female patients with thalassemia. J Pediatr Endocrinol Metab 1998 11 (Suppl 3 935 43.
3. Karagiorga-Lagana M. Fertility in thalassemia: the Greek experience. J Pediatr Endocrinol Metab 1998 11 (Suppl 3 945 51.
4. Anderson LJ, Holden S, Davis B, et al. Cardiovascular T2* magnetic resonance for the early diagnosis of myocardial iron overload. Eur Heart J 2001 22 : 2171.
5. St. Pierre T, Clark P, Chua-anusorn W, et al. Noninvasive measurement and imaging of liver iron concentrations using proton magnetic resonance. Blood 2005 1052 : 855 61.
6. Wood JC, Enriquez C, Ghugre N, Tyzka JM, Carson S, Nelson MD, Coates T. MRI R2 and R2* mapping accurately estimates hepatic iron concentration in transfusion-dependent thalassemia and sickle-cell disease patients. Blood 2005 106 : 1460 5.
7. Singer ST, Vichinsky EP. Deferoxamine treatment during pregnancy: is it harmful? Am J Hematol 1999 60 : 24 6.
8. Sohn YS, Breuer W, Munnich A, Cabantchik ZI. Redistribution of accumulated cell iron: a modality of chelation with therapeutic implications. Blood 2008 111 : 1690 9.