IgLON cell adhesion molecule Kilon is a crucial modulator for synapse number in hippocampal neurons

Brain Research

Volumn 1224, Issue , 2008, Pages 1-11

  Hashimoto, Takashi ^a   Yamada, Mayumi ^a,b   Maekawa, Shohei ^c   Nakashima, Toshihiro ^a   Miyata, Seiji ^a  

^a KYOTO INSTITUTE OF TECHNOLOGY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c KOBE UNIVERSITY   (Japan)

Author keywords

Cell adhesion molecule; Detergent; Iglon; Immunoglobulin superfamily; Synaptogenesis

Indexed keywords

CELL ADHESION MOLECULE; IMMUNOGLOBULIN; KILON; PLASMID VECTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; GENE; GENE OVEREXPRESSION; HIPPOCAMPUS; IMMUNOCYTOCHEMISTRY; KILON GENE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SYNAPTIC POTENTIAL; SYNAPTOGENESIS; WESTERN BLOTTING;

ANIMALS; BIOLOGICAL MARKERS; CELL ADHESION MOLECULES, NEURONAL; CELL DIFFERENTIATION; CELLS, CULTURED; CHO CELLS; CRICETINAE; CRICETULUS; DENDRITES; DETERGENTS; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HIPPOCAMPUS; NEURONS; PRESYNAPTIC TERMINALS; RATS; RATS, WISTAR; SOLUBILITY; SYNAPSES; SYNAPSINS; TRANSFECTION;

EID: 47649105358     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2008.05.069     Document Type: Article

References (58)

1. Biederer T., Sara Y., Mozhayeva M., Atasoy D., Liu X., Kavalali E.T., and Südhof T.C. SynCAM, a synaptic adhesion molecule that drives synapse assembly. Science 297 (2002) 1525-1531
2. Bräuer A.U., Savaskan N.E., Plaschke M., Prehn S., Ninnemann O., and Nitsch R. Ig-molecule kilon shows differential expression pattern from LAMP in the developing and adult rat hippocampus. Hippocampus 10 (2000) 632-644
3. Cho T.M., Hasegawa J., Ge B., and Loh H.H. Purification to apparent homogeneity of a m-type opioid receptor from rat brains. Proc. Natl. Acad. Sci. USA 83 (1986) 4138-4142
4. Eagleson K.L., Pimenta A.F., Burns M.M., Fairfull L.D., Cornuet P.K., Zhang L., and Levitt P. Distinct domains of the limbic system-associated membrane protein (LAMP) mediate discrete effects on neurite outgrowth. Mol. Cell. Neurosci. 24 (2003) 725-740
5. Funatsu N., Miyata S., Kumanogoh H., Shigeta M., Hamada K., Endo Y., Sokawa Y., and Maekawa S. Characterization of a novel rat brain glycosylphosphatidylinositol-anchored protein (Kilon), a member of the IgLON cell adhesion molecule family. J. Biol. Chem. 274 (1999) 8224-8230
6. Gil O.D., Zanazzi G., Struyk A.F., and Salzer J.L. Neurotrimin mediates bifunctional effects on neurite outgrowth via homophilic and heterophilic interactions. J. Neurosci. 18 (1998) 9312-9325
7. Gil O.D., Zhang L., Chen S., Ren Y.Q., Pimenta A., Zanazzi G., Hillman D., Levitt P., and Salzer J.L. Complementary expression and heterophilic interactions between IgLON family members neurotrimin and LAMP. J. Neurobiol. 51 (2002) 190-240
8. Gerrow K., and El-Husseini A. Cell adhesion molecules at the synapse. Front. Biosci. 11 (2006) 2400-2419
9. Goda Y., and Davis G.W. Mechanisms of synapse assembly and disassembly. Neuron 40 (2003) 243-264
10. Hering H., Lin C.-C., and Sheng M. Lipid rafts in the maintenance of synapses, dendritic spines, and surface AMPA receptor stability. J. Neurosci. 23 (2003) 3262-3271
11. De Hoop M., von Poser C., Lange C., Ikonen E., Hunziker W., and Dotti C.G.J. Intracellular routing of wild-type and mutated polymeric immunoglobulin receptor in hippocampal neurons in culture. Cell. Biol. 130 (1995) 1447-1459
12. Horton H.L., and Levitt P. A unique membrane protein is expressed on early development of the limbic system axons and cortical targets. J. Neurosci. 8 (1988) 4653-4661
13. Ledesma M.D., Simons K., and Dotti C.G. Neuronal polarity: essential role of protein-lipid complexes in axonal sorting. Proc. Natl. Acad. Sci. USA. 95 (1998) 3966-3971
14. Levitt P. A monoclonal antibody to limbic system neurons. Science 223 (1984) 299-301
15. Li P., Prasad S.S., Mitchell D.E., Hachisuka A., Sawada J.I., Al-Housseini A.M., and Gu Q. Postnatal expression profile of OBCAM implies its involvement in visual cortex development and plasticity. Cereb. Cortex 16 (2005) 291-299
16. Lodge A.P., Mark R.H., McNamee C.J., and Moss D.J. Co-localization, heterophilic interactions and regulated expression of IgLON family proteins in the chick nervous system. Mol. Brain Res. 82 (2000) 84-94
17. Maekawa S., Iino S., and Miyata S. Molecular characterization of the detergent-insoluble cholesterol-rich membrane microdomain (raft) of the central nervous system. Biochem. Biophys. Acta. 1610 (2003) 261-270
18. Mann F., Zhukareva V., Pimenta A., Levitt P., and Bolz J. Membrane-associated molecules guide limbic and nonlimbic thalamocortical projections. J. Neurosci. 18 (1998) 9409-9419
19. Marg A., Sirim P., Spaltmann F., Plagge A., Kauselmann G., Buck F., Rathjen F.G., and Brummendorf T. Neurotractin, a novel neurite outgrowth-promoting Ig-like protein that interacts with CEPU-1 and LAMP. J. Cell Biol. 145 (1999) 865-876
20. Matus A. Actin-based plasticity in dendritic spines. Science 290 (2000) 754-758
21. Miyata S., Funatsu N., Matsunaga W., Kiyohara T., Sokawa Y., and Maekawa S. Expression of the IgLON cell adhesion molecules Kilon and OBCAM in hypothalamic magnocellular neurons. J. Comp. Neurol. 424 (2000) 74-85
22. Miyata S., Takamatsu S., Maekawa S., Matsumoto N., Taguchi K., Watanabe K., Kiyohara T., and Hatton G.I. Plasticity of neurohypophysial terminals with increased hormonal release during dehydration: ultrastructural and biochemical analyses. J. Comp. Neurol. 343 (2001) 413-427
23. Miyata S., Matsumoto N., Taguchi K., Akagi A., Iino T., Funatsu N., and Maekawa S. Biochemical and ultrastructural analyses of IgLON cell adhesion molecules, Kilon and OBCAM in the rat brain. Neuroscience 117 (2003) 645-658
24. Miyata S., Matsumoto N., and Maekawa S. Polarized targeting of IgLON cell adhesion molecule OBCAM to dendrites in cultured neurons. Brain Res. 979 (2003) 129-136
25. Mizoguchi A., Nakanishi H., Kimura K., Matsubara K., Ozaki-Kuroda K., Katata T., Honda T., Kiyohara Y., Heo K., Higashi M., Tsutsumi T., Sonoda S., Ide C., and Takai Y. Nectin: an adhesion molecule involved in formation of synapses. J. Cell Biol. 156 (2002) 555-565
26. Nam C.I., and Chen L. Postsynaptic assembly induced by neurexin-NL interaction and neurotransmitter. Proc. Natl. Acad. Sci. U.S.A. 102 (2005) 6137-6142
27. Ntougkos E., Rush R., Scott D., Frankenberg T., Gabra H., Smyth J.F., and Sellar G.C. The IgLON family in epithelial ovarian cancer: expression profiles and clinicopathologic correlates. Clin. Cancer Res. 11 (2005) 5764-5768
28. Okamura K., Tanaka H., Yagita Y., Saeki Y., Taguchi A., Hiraoka Y., Zeng L.Z., Colman D.R., and Miki N. Cadherin activity is required for activity-induced spine remodeling. J. Cell Biol. 167 (2004) 961-972
29. Olive S., Dubois C., Schachner M., and Rougon G. The F3 neuronal glycosylphosphatidylinositol-linked molecule is localized to glycolipid-enriched membrane subdomains and interacts with L1 and fyn kinase in cerebellum. J. Neurochem. 65 (1995) 2307-2317
30. Paladino S., Sarnataro D., Pillich R., Tivodar S., Nitsch L., and Zurzolo C. Protein oligomerization modulates raft partitioning and apical sorting of GPI-anchored proteins. J. Cell Biol. 167 (2004) 699-709
31. Pietrini G., Suh Y.J., Edelmann L., Rudnick G., and Caplan M.J. The axonal gamma-aminobutyric acid transporter GAT-1 is sorted to the apical membranes of polarized epithelial cells. J. Biol. Cehm. 269 (1994) 4668-4674
32. Pimenta A.F., Zhukareva V., Barbe M.F., Reinoso B.S., Grimley C., Henzel W., Fischer I., and Levitt P. The limbic system-associated membrane protein is an Ig superfamily member that mediates selective neuronal growth and axon targeting. Neuron 15 (1995) 287-297
33. Pimenta A.F., Reinoso B.S., and Levitt P. Expression of the mRNAs encoding the limbic system-associated membrane protein (LAMP): II. Fetal rat brain. J. Comp. Neurol. 375 (1996) 289-302
34. Pimenta A.F., and Levitt P. Characterization of the genomic structure of the mouse limbic system-associated membrane protein (Lsamp) gene. Genomics. 83 (2004) 790-801
35. Reed J., McNamee C., Rackstraw S., Jenkins J., and Moos D. Diglons are heterodimeric proteins composed of IgLON subunits, and Diglon-CO inhibits neurite outgrowth from cerebellar granule cells. J Cell Sci. 117 (2004) 3961-3973
36. Reinoso B.S., Pimenta A.F., and Levitt P. Expression of the mRNAs encoding the limbic system-associated membrane protein (LAMP): II. Adult rat brain. J. Comp. Neurol. 375 (1996) 274-288
37. Rougon G., and Hobert O. New insights into the diversity and function of neuronal immunoglobulin superfamily molecules. Annu. Rev. Neurosci. 26 (2003) 207-238
38. Ruoslahti E. Fibronectin and its receptors. Annu. Rev. Biochem. 57 (1988) 375-413
39. Salzer J.L., and Colman D.R. Mechanisms of cell adhesion in the nervous system: role of the immunoglobulin gene superfamily. Dev. Neurosci. 11 (1989) 377-390
40. Schäfer M., Bräuer A.J., Savaskan N.E., Rathjen F.G., and Brümmendorf T. Neurotractin/kilon promotes neurite outgrowth and is expressed on reactive astrocytes after entorhinal cortex lesion. Mol. Cell. Neurosci. 29 (2005) 580-590
41. Scheiffele P., Fan J., Choih J., Fetter R., and Serafini T. Neuroligin expressed in nonneuronal cells triggers presynaptic development in contacting axons. Cell 101 (2000) 657-669
42. Schofield P.R., McFarland K.C., Hayflick J.S., Wilcox J.N., Cho T.M., Roy S., Lee N.M., Loh H., and Seeburg P.H. Molecular characterization of a new immunoglobulin superfamily protein with potential roles in opioid binding and cell contact. EMBO J. 8 (1989) 489-495
43. Sellar G.C., Watt K.P., Rabiasz G.J., Stronach E.A., Li L., Miller E.P., Massie C.E., Miller J., Contreas-Moreira B., Scott D., Brown I., Williams A.R., Bates P.A., Smyth J.F., and Gabra H. OPCML at 11q25 is epigenetically inactivated and has tumor-suppressor function in epithelial ovarian cancer. Nat. Genet. 34 (2003) 337-343
44. Sheng M., and Kim M.J. Postsynaptic signaling and plasticity mechanisms. Science 298 (2002) 776-780
45. Struyk A.F., Canoll P.D., Wolfgang M.J., Rosen C.J., D'Eustachio P., and Salzer J.L. Cloning of neurotrimin defines a new subfamily of differentially expressed neural cell adhesion molecules. J. Neurosci. 15 (1995) 2141-2156
46. Takeichi M. The cadherin: cell-cell adhesion molecules controlling animal morphogenesis. Development 102 (1988) 639-655
47. Tanaka H., Shan W., Phillips G.R., Arndt K., Bozdagi O., Shapiro L., Huntley G.W., Benson D.L., and Colman D.R. Molecular modification of N-cadherin in response to synaptic activity. Neuron 25 (2000) 93-107
48. Taniguchi H., Gollan L., Scholl F.G., Mahadomrongkul V., Dobler E., Limthong N., Peck M., Aoki C., and Scheiffele P. Silence of neuroligin function by postsynaptic neurexins. J. Neurosci. 27 (2007) 2815-2824
49. Thies E., and Mandelkow E.M. Missorting of tau in neurons causes degeneration of synapses that can be rescued by the kinase MARK2/Par-1. J. Neurosci. 27 (2007) 2896-2907
50. Togashi H., Abe K., Mizoguchi A., Takaoka K., Chisaka O., and Takeichi M. Cadherin regulates dendritic spine morphogenesis. Neuron 35 (2002) 77-89
51. Williams A.F., and Barclay A.N. The immunoglobulin super family: domains for cell surface recognition. Annu. Rev. Immunol. 6 (1988) 381-405
52. Yamada M., Hashimoto T., Hayashi N., Higuchi M., Murakami A., Nakashima T., Maekawa S., and Miyata S. Synaptic adhesion molecule OBCAM; synaptogenesis and dynamic internalization. Brain Res. 1165 (2007) 5-14
53. Yuste R., and Denk W. Dendritic spines as basic functional units of neuronal integration. Nature 375 (1995) 682-684
54. Yu X., and Malenka R.C. b-catenin is critical for dendritic morphogenesis. Nat. Neurosci. 11 (2003) 1169-1177
55. Zacco A., Cooper V., Chantler P., Fisher-Hyland S., Horton H.L., and Levitt P. Isolation, biochemical characterization and ultrastructural analysis of the limbic system-associated membrane protein (LAMP), a protein expressed by neurons comprising functional neural circuits. J. Neuorsci. 10 (1990) 73-90
56. Zhang H., Webb D.J., Asmussen H., and Horwitz A.F. Synapse formation is regulated by the signaling adaptor GIT1. J. Cell Biol. 161 (2003) 131-142
57. 2+ increase in primary fetal neurons. Mol. Cell. Neurosci. 10 (1997) 43-55
58. Zisch A.H., D'Alessandri L., Amrein K., Ranscht B., Winterhalter K.H., and Vaughan L. The glypiated neuronal cell adhesion molecule contactin/F11 complexes with src-family protein tyrosine kinase Fyn. Mol. Cell Neurosci. 6 (1995) 263-279