A multivariate genetic analysis of specific phobia, separation anxiety and social phobia in early childhood

Journal of Abnormal Child Psychology

Volumn 36, Issue 6, 2008, Pages 839-848

  Eley, Thalia C ^a   Rijsdijk, Fruhling V ^a   Perrin, Sean ^a   O'Connor, Thomas G ^b   Bolton, Derek ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

Anxiety disorders; Children; Environment; Genetics; Twins

Indexed keywords

ARTICLE; COMORBIDITY; CONTROLLED STUDY; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DIZYGOTIC TWINS; ENVIRONMENTAL FACTOR; FEMALE; GENETIC ANALYSIS; HUMAN; INTERVIEW; MAJOR CLINICAL STUDY; MALE; MONOZYGOTIC TWINS; MULTIVARIATE ANALYSIS; PATIENT ASSESSMENT; PHENOTYPE; PHOBIA; PRESCHOOL CHILD; SEPARATION ANXIETY; SOCIAL PHOBIA;

ADULT; ANXIETY DISORDERS; ANXIETY, SEPARATION; CHILD; COMORBIDITY; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; FEMALE; HUMANS; MALE; PHOBIC DISORDERS; TWINS; YOUNG ADULT;

EID: 47549113324     PISSN: 00910627     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10802-008-9216-x     Document Type: Article

References (44)

1. A. Angold E. J. Costello 1993 Depressive comorbidity in children and adolescents: empirical, theoretical, and methodological issues American Journal of Psychiatry 150 1779 1791
2. S. M. Bogels M. L. Brechman-Toussaint 2006 Family issues in child anxiety: Attachment, family functioning, parental rearing and beliefs Clinical Psychology Review 26 834 856
3. D. Bolton T. C. Eley T. G. O'Connor S. Perrin S. Rabe-Hesketh F. V. Rijsdijk 2006 Prevalence and genetic and environmental influences on anxiety disorders in 6-year-old twins Psychological Medicine 36 335 344
4. T. A. Brown D. H. Barlow 1992 Comorbidity among anxiety disorders: Implications for treatment and DSM-IV Journal of Consulting and Clinical Psychology 60 835 844
5. S. E. Bruce K. A. Yonkers M. W. Otto J. L. Eisen R. B. Weisberg M. Pagano 2005 Influence of psychiatric comorbidity on recovery and recurrence in generalized anxiety disorder, Social Phobia, and panic disorder: A 12-year prospective study American Journal of Psychiatry 162 1179 1187
6. B. F. Chorpita T. A. Brown D. H. Barlow 1998 Perceived control as a mediator of family environment in etiological models of childhood anxiety Behavior Therapy 29 457 476
7. V. E. Cobham M. R. Dadds S. H. Spence 1998 The role of parental anxiety in the treatment of childhood anxiety Journal of Consulting & Clinical Psychology 66 893 905
8. J. A. Cohen 1960 A coefficient of agreement for nominal scales Educational and Psychological Measurement 20 37 46
9. E. J. Costello S. Mustillo A. Erkanli G. Keeler A. Angold 2003 Prevalence and development of psychiatric disorders in childhood and adolescence Archives of General Psychiatry 60 837 844
10. L. J. Eaves J. L. Silberg J. M. Meyer H. H. Maes E. Simonoff A. Pickles 1997 Genetics and developmental psychopathology: 2. The main effects of genes and environment on behavioral problems in the Virginia Twin Study of Adolescent Behavioral Development Journal of Child Psychology and Psychiatry 38 965 980
11. T. C. Eley D. Bolton T. G. O'Connor S. Perrin P. Smith R. Plomin 2003 A twin study of anxiety-related behaviours in pre-school children Journal of Child Psychology and Psychiatry 44 945 960
12. T. C. Eley J. Stevenson 1999 Using genetic analyses to clarify the distinction between depressive and anxious symptoms in children and adolescents Journal of Abnormal Child Psychology 27 105 114
13. C. A. Essau J. Conradt F. Petermann 2000 Frequency, comorbidity, and psychosocial impairment of anxiety disorders in German adolescents Journal of Anxiety Disorders 14 263 279
14. S. A. Feigon I. D. Waldman F. Levy D. A. Hay 2001 Genetic and environmental influences on Separation Anxiety disorder symptoms and their moderation by age and sex Behavior Genetics 31 403 411
15. A. P. Field J. E. Ball N. J. Kawycz H. Moore 2007 Parent-child relationships and the verbal information pathway to fear in children: Two preliminary experiments Behavioural and Cognitive Psychotherapy 35 473 486
16. R. Goodman 1997 The strengths and difficulties questionnaire Journal of Child Psychology & Psychiatry 39 581 586
17. A. M. Gregory T. C. Eley 2007 Genetic influences on anxiety in children: What we've learned and where we're heading Clinical Child and Family Psychology Review 10 199 212
18. Kendler, K. S. (1996). Major depression and generalised anxiety disorder. Same genes, (partly)different environments-revisited. British Journal of Psychiatry Supplement, 68-75.
19. E. Kortlander P. C. Kendall S. M. Panichelli-Mindel 1997 Maternal expectations and attributions about coping in anxious children Journal of Anxiety Disorders 11 297 315
20. C. G. Last C. C. Strauss G. Francis 1987 Comorbidity among childhood anxiety disorders Journal of Nervous and Mental Disease 175 726 730
21. P. Lichtenstein P. Annas 2000 Heritability and prevalence of specific fears and phobia in childhood Journal of Child Psychology & Psychiatry 41 927 937
22. N. Martin D. I. Boomsma G. Machin 1997 A twin-pronged attack on complex trait Nature Genetics 17 387 392
23. Maser, J. D., & Cloninger, C. R. (1990). Comorbidity of mood and anxiety disorders. Washington, DC: American Psychiatric Press.
24. K. R. Merikangas J. Angst 1995 Comorbidity and Social Phobia: Evidence from clinical, epidemiologic, and genetic studies European Archives of Psychiatry and Clinical Neuroscience 244 297 303
25. Neale, M. (1999). Mx: Statistical modeling (5th ed.). Richmond, VA 23298: Department of Psychiatry.
26. Neale, M., & Cardon, L. (1992). Methodology for genetic studies of twins and families. Dordrecht: Kluwer Academic Publications.
27. M. C. Neale M. B. Miller 1997 The use of likelihoodbased confidence intervals in genetic models Behavior Genetics 27 113 120
28. Oest, L. G., & Treffers, P. D. A. (2001). Onset, course, and outcome for anxiety disorders in children. In W. K. Silverman, & P. D. A. Treffers (Eds.) Anxiety disorders in children and adoelscents: Research, assessment and intervention. Cambridge Child and Adolescent Psychiatry (pp. 293-312). New York: Cambridge University Press.
29. A. Ogliari A. Citterio A. Zanoni C. Fagnani V. Patriarca R. Cirrincione 2006 Genetic and environmental influences on anxiety dimensions in Italian twins evaluated with the SCARED questionnaire Journal of Anxiety Disorders 20 760 777
30. M. W. Otto M. H. Pollack K. M. Maki R. A. Gould J. J. Worthington III J. W. Smoller 2001 Childhood history of anxiety disorders among adults with Social Phobia: Rates, correlates, and comparisons with patients with panic disorder Depression and Anxiety 14 209 213
31. Perrin, S., & Last, C. G. (1995). Dealing with comorbidity. In A. R. Eisen, C. A. Kearney, & C. E. Schaefer (Eds.) Clinical handbook of anxiety disorders in children and adolescents (pp. 412-435). Lanham, MD, US: Jason Aronson.
32. M. H. Pollack 2001 Comorbidity, neurobiology, and pharmacotherapy of social anxiety disorder Journal of Clinical Psychiatry 62 Suppl 12 24 29
33. S. Rachman 2002 Fears born and bred: Non-associative fear acquisition? Behaviour Research and Therapy 40 121 126
34. P. Rohde P. Lewinsohn J. Seeley 1997 Comparability of telephone and face to face interviews in assessing axis I and II disorders American Journal of Psychiatry 154 1593 1598
35. F. R. Schneier J. Johnson C. D. Hornig M. R. Liebowitz M. M. Weissman 1992 Social Phobia. Comorbidity and morbidity in an epidemiologic sample Archives of General Psychiatry 49 282 288
36. P. C. Sham A. Sterne S. Purcell S. S. Cherny M. Webster F. V. Rijsdijk 2000 GENESiS: Creating a composite index of the vulnerability to anxiety and depression in a community-based sample of siblings Twin Research 3 316 322
37. J. L. Silberg M. Rutter L. Eaves 2001 Genetic and environmental influences on the temporal association between earlier anxiety and later depression in girls Biological Psychiatry 49 1040 1049 [erratum appears in Biol Psychiatry 2001 Sep 1;50(5):393.]
38. W. K. Silverman A. R. Eisen 1992 Age differences in the reliability of parental and child reports of child-anxious symptomatology using a structured interview Journal of the American Academy of Child and Adolescent Psychiatry 31 117 124
39. W. K. Silverman W. B. Nelles 1998 The anxiety disorders interview schedule for children Journal of American Academy of Child and Adolescent Psychiatry 27 772 778
40. W. K. Silverman B. Rabian 1995 Test-retest reliability of the DSM-III-R childhood anxiety disorders symptoms using the Anxiety Disorders Interview Schedule for Children Journal of Anxiety Disorders 9 139 150
41. C. Sobin M. Weissman R. B. Goldstein P. Adams 1993 Diagnostic interviewing for family studies: Comparing telephone and face to face methods for diagnosis of lifetime psychiatric disorders Psychiatric Genetics 3 227 233
42. J. Stevenson N. Batten M. Cherner 1992 Fears and fearfulness in children and adolescents: A genetic analysis of twin data Journal of Child Psychology and Psychiatry 33 977 985
43. T. D. Topolski J. K. Hewitt L. J. Eaves J. L. Silberg J. M. Meyer M. Rutter 1997 Genetic and environmental influences on child reports of manifest anxiety and symptoms of Separation Anxiety and overanxious disorders: A community-based twin study Behavior Genetics 27 15 28
44. A. Trouton F. M. Spinath R. Plomin 2002 Twins Early Development Study (TEDS): A multivariate, longitudinal genetic investigation of language, cognition and behaviour problems in childhood Twin Research 5 444 448