Polymorphisms in manganese superoxide dismutase, myeloperoxidase and glutathione-S-transferase and survival after treatment for metastatic breast cancer

Breast Cancer Research and Treatment

Volumn 111, Issue 1, 2008, Pages 93-101

  Bewick, Mary A ^a   Conlon, Michael S C ^a   Lafrenie, Robert M ^a,b  

^a SUDBURY REGIONAL HOSPITAL   (Canada)

^b NORTHERN ONTARIO SCHOOL OF MEDICINE   (Canada)

Author keywords

Drug metabolism; Metastatic breast cancer; Polymorphisms; Survival

Indexed keywords

ALANINE; CARBOPLATIN; CISPLATIN; CYCLOPHOSPHAMIDE; DAUNORUBICIN; DNA; DOCETAXEL; DOXORUBICIN; EPIRUBICIN; FLUOROURACIL; FOLIC ACID ANTAGONIST; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE P1; ISOLEUCINE; MANGANESE SUPEROXIDE DISMUTASE; MITOXANTRONE; MYELOPEROXIDASE; OXALIPLATIN; PACLITAXEL; THIOTEPA; VALINE; VINBLASTINE; VINCRISTINE;

ADULT; ARTICLE; AUTOLOGOUS STEM CELL TRANSPLANTATION; BREAST CANCER; CANCER CHEMOTHERAPY; CANCER PALLIATIVE THERAPY; CANCER SURVIVAL; DISEASE FREE SURVIVAL; DRUG EFFICACY; DRUG MEGADOSE; DRUG METABOLISM; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; METASTASIS; PRIORITY JOURNAL; PROMOTER REGION; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; COMBINED MODALITY THERAPY; DISEASE-FREE SURVIVAL; FEMALE; GENOTYPE; GLUTATHIONE TRANSFERASE; HUMANS; KAPLAN-MEIERS ESTIMATE; METABOLIC DETOXICATION, DRUG; MIDDLE AGED; PEROXIDASE; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; STEM CELL TRANSPLANTATION; SUPEROXIDE DISMUTASE;

EID: 47549108099     PISSN: 01676806     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10549-007-9764-8     Document Type: Article

References (48)

1. JD Hayes RC Strange 2000 Glutathione S-transferase polymorphisms and their biological consequences Pharmacology 61 154 166
2. G Liu W Zhou LI Wang S Park DP Miller LL Xu JC Wain TJ Lynch L Su DC Christiani 2004 MPO and SOD2 polymorphisms, gender, and the risk of non-small cell lung carcinoma Cancer Lett 214 69 79
3. SH Olson MD Carlson H Ostrer S Harlap A Stone M Winters CB Ambrosone 2004 Genetic variants in SOD2, MPO, and NQO1, and risk of ovarian cancer Gynecol Oncol 93 615 620
4. G Yang XO Shu ZX Ruan QY Cai F Jin YT Gao W Zheng 2005 Genetic polymorphisms in glutathione-S-transferase genes (GSTM1, GSTT1, GSTP1) and survival after chemotherapy for invasive breast carcinoma Cancer 103 52 58
5. CB Ambrosone J Ahn KK Singh H Rezaishiraz H Furberg C Sweeney B Coles A Trovato 2005 Polymorphisms in genes related to oxidative stress (MPO, MnSOD, CAT) and survival after treatment for breast cancer Cancer Res 65 1105 1111
6. A Beeghly D Katsaros H Chen S Fracchioli Y Zhang M Massobrio H Risch B Jones H Yu 2006 Glutathione S-transferase polymorphisms and ovarian cancer treatment and survival Gynecol Oncol 100 330 337
7. KA Conklin 2004 Chemotherapy-associated oxidative stress: impact on chemotherapeutic effectiveness Integr Cancer Ther 3 294 300
8. NI Weijl FJ Cleton S Osanto 1997 Free radicals and antioxidants in chemotherapy-induced toxicity Cancer Treat Rev 23 209 240
9. TF La A Orlando A Silipigni T Giacobello S Pergolizzi M Aragona 1997 Increase of oxygen free radicals and their derivatives in chemo- and radiation treated neoplasm patients Minerva Med 88 121 126
10. M Lopez-Lazaro 2006 Dual role of hydrogen peroxide in cancer: possible relevance to cancer chemoprevention and therapy Cancer Lett 252 1 8
11. J Alexandre F Batteux C Nicco C Chereau A Laurent L Guillevin B Weill F Goldwasser 2006 Accumulation of hydrogen peroxide is an early and crucial step for paclitaxel-induced cancer cell death both in vitro and in vivo Int J Cancer 119 41 48
12. B Ramanathan KY Jan CH Chen TC Hour HJ Yu YS Pu 2005 Resistance to paclitaxel is proportional to cellular total antioxidant capacity Cancer Res 65 8455 8460
13. A Sutton A Imbert A Igoudjil V Descatoire S Cazanave D Pessayre F Degoul 2005 The manganese superoxide dismutase Ala16Val dimorphism modulates both mitochondrial import and mRNA stability Pharmacogenet Genomics 15 311 319
14. CB Ambrosone JL Freudenheim PA Thompson E Bowman JE Vena JR Marshall S Graham R Laughlin T Nemoto PG Shields 1999 Manganese superoxide dismutase (MnSOD) genetic polymorphisms, dietary antioxidants, and risk of breast cancer Cancer Res 59 602 606
15. K Mitrunen P Sillanpaa V Kataja M Eskelinen VM Kosma S Benhamou M Uusitupa A Hirvonen 2001 Association between manganese superoxide dismutase (MnSOD) gene polymorphism and breast cancer risk Carcinogenesis 22 827 829
16. J Stoehlmacher SA Ingles DJ Park W Zhang HJ Lenz 2002 The -9Ala/-9Val polymorphism in the mitochondrial targeting sequence of the manganese superoxide dismutase gene (MnSOD) is associated with age among Hispanics with colorectal carcinoma Oncol Rep 9 235 238
17. K Woodson JA Tangrea TA Lehman R Modali KM Taylor K Snyder PR Taylor J Virtamo D Albanes 2003 Manganese superoxide dismutase (MnSOD) polymorphism, alpha-tocopherol supplementation and prostate cancer risk in the alpha-tocopherol, beta-carotene cancer prevention study (Finland) Cancer Causes Control 14 513 518
18. RJ Hung P Boffetta P Brennan C Malaveille U Gelatti D Placidi A Carta A Hautefeuille S Porru 2004 Genetic polymorphisms of MPO, COMT, MnSOD, NQO1, interactions with environmental exposures and bladder cancer risk Carcinogenesis 25 973 978
19. DI Pattison MJ Davies 2006 Reactions of myeloperoxidase-derived oxidants with biological substrates: gaining chemical insight into human inflammatory diseases Curr Med Chem 13 3271 3290
20. SJ Klebanoff 1999 Myeloperoxidase Proc Assoc Am Physicians 111 383 389
21. H Dally K Gassner B Jager P Schmezer B Spiegelhalder L Edler P Drings H Dienemann V Schulz K Kayser 2002 Myeloperoxidase (MPO) genotype and lung cancer histologic types: the MPO -463 A allele is associated with reduced risk for small cell lung cancer in smokers Int J Cancer 102 530 535
22. FJ Piedrafita RB Molander G Vansant EA Orlova M Pfahl WF Reynolds 1996 An Alu element in the myeloperoxidase promoter contains a composite SP1-thyroid hormone-retinoic acid response element J Biol Chem 271 14412 14420
23. X Wu MB Schabath MR Spitz 2003 Myeloperoxidase promoter region polymorphism and lung cancer risk Methods Mol Med 75 121 133
24. A Feyler A Voho C Bouchardy K Kuokkanen P Dayer A Hirvonen S Benhamou 2002 Point: myeloperoxidase -463G -> a polymorphism and lung cancer risk Cancer Epidemiol Biomarkers Prev 11 1550 1554
25. K Matsuo N Hamajima M Shinoda S Hatooka M Inoue T Takezaki H Onda K Tajima 2001 Possible risk reduction in esophageal cancer associated with MPO -463 A allele J Epidemiol 11 109 114
26. JD Hayes LI McLellan 1999 Glutathione and glutathione-dependent enzymes represent a co-ordinately regulated defence against oxidative stress Free Radic Res 31 273 300
27. TM Bosch I Meijerman JH Beijnen JH Schellens 2006 Genetic polymorphisms of drug-metabolising enzymes and drug transporters in the chemotherapeutic treatment of cancer Clin Pharmacokinet 45 253 285
28. L Gate KD Tew 2001 Glutathione S-transferases as emerging therapeutic targets Expert Opin Ther Targets 5 477 489
29. CC McIlwain DM Townsend KD Tew 2006 Glutathione S-transferase polymorphisms: cancer incidence and therapy Oncogene 25 1639 1648
30. U Pandya SK Srivastava SS Singhal A Pal S Awasthi P Zimniak YC Awasthi SV Singh 2000 Activity of allelic variants of Pi class human glutathione S-transferase toward chlorambucil Biochem Biophys Res Commun 278 258 262
31. X Hu H Xia SK Srivastava A Pal YC Awasthi P Zimniak SV Singh 1998 Catalytic efficiencies of allelic variants of human glutathione S-transferase P1-1 toward carcinogenic anti-diol epoxides of benzo[c]phenanthrene and benzo[g]chrysene Cancer Res 58 5340 5343
32. TM Ishimoto F li-Osman 2002 Allelic variants of the human glutathione S-transferase P1 gene confer differential cytoprotection against anticancer agents in Escherichia coli Pharmacogenetics 12 543 553
33. C Sweeney GY McClure MY Fares A Stone BF Coles PA Thompson S Korourian LF Hutchins FF Kadlubar CB Ambrosone 2000 Association between survival after treatment for breast cancer and glutathione S-transferase P1 Ile105Val polymorphism Cancer Res 60 5621 5624
34. RK Dasgupta PJ Adamson FE Davies S Rollinson PL Roddam AJ Ashcroft AM Dring JA Fenton JA Child JM Allan 2003 Polymorphic variation in GSTP1 modulates outcome following therapy for multiple myeloma Blood 102 2345 2350
35. JM Lee MT Wu YC Lee SY Yang JS Chen HH Hsu PM Huang SW Kuo CJ Lee CJ Chen 2005 Association of GSTP1 polymorphism and survival for esophageal cancer Clin Cancer Res 11 4749 4753
36. MA Bewick MS Conlon RM Lafrenie 2006 Polymorphisms in XRCC1, XRCC3, and CCND1 and survival after treatment for metastatic breast cancer J Clin Oncol 24 5645 5651
37. National Cancer Institute (2007) Cancer genome anatomy project. SNP500 cancer database. http://snp500cancer.nci.nih.gov/snplist.cfm
38. U Brockstedt M Krajinovic C Richer G Mathonnet D Sinnett W Pfau D Labuda 2002 Analyses of bulky DNA adduct levels in human breast tissue and genetic polymorphisms of cytochromes P450 (CYPs), myeloperoxidase (MPO), quinone oxidoreductase (NQO1), and glutathione S-transferases (GSTs) Mutat Res 516 41 47
39. CB Ambrosone C Sweeney BF Coles PA Thompson GY McClure S Korourian MY Fares A Stone FF Kadlubar LF Hutchins 2001 Polymorphisms in glutathione S-transferases (GSTM1 and GSTT1) and survival after treatment for breast cancer Cancer Res 61 7130 7135
40. C Sweeney V Nazar-Stewart PL Stapleton DL Eaton TL Vaughan 2003 Glutathione S-transferase M1, T1, and P1 polymorphisms and survival among lung cancer patients Cancer Epidemiol Biomarkers Prev 12 527 533
41. EJ Kim P Jeong C Quan J Kim SC Bae SJ Yoon JW Kang SC Lee WJ Jun WJ Kim 2005 Genotypes of TNF-alpha, VEGF, hOGG1, GSTM1, and GSTT1: useful determinants for clinical outcome of bladder cancer Urology 65 70 75
42. E Goekkurt S Hoehn C Wolschke C Wittmer C Stueber DK Hossfeld J Stoehlmacher 2006 Polymorphisms of glutathione S-transferases (GST) and thymidylate synthase (TS)-novel predictors for response and survival in gastric cancer patients Br J Cancer 94 281 286
43. U Gonlugur H Pinarbasi TE Gonlugur Y Silig 2006 The association between polymorphisms in glutathione S-transferase (GSTM1 and GSTT1) and lung cancer outcome Cancer Invest 24 497 501
44. E Barragan M Collado J Cervera G Martin P Bolufer J Roman MA Sanz 2006 The GST deletions and NQO1*2 polymorphism confers interindividual variability of response to treatment in patients with acute myeloid leukemia Leuk Res 31 947 953
45. J Stoehlmacher DJ Park W Zhang S Groshen DD Tsao-Wei MC Yu HJ Lenz 2002 Association between glutathione S-transferase P1, T1, and M1 genetic polymorphism and survival of patients with metastatic colorectal cancer J Natl Cancer Inst 94 936 942
46. XF Sun A Ahmadi G Arbman A Wallin D Asklid H Zhang 2005 Polymorphisms in sulfotransferase 1A1 and glutathione S-transferase P1 genes in relation to colorectal cancer risk and patients' survival World J Gastroenterol 11 6875 6879
47. SL Holley R Rajagopal PR Hoban M Deakin AS Fawole JB Elder J Elder V Smith RC Strange AA Fryer 2006 Polymorphisms in the glutathione S-transferase mu cluster are associated with tumour progression and patient outcome in colorectal cancer Int J Oncol 28 231 236
48. EL Goode AM Dunning B Kuschel CS Healey NE Day BA Ponder DF Easton PP Pharoah 2002 Effect of germ-line genetic variation on breast cancer survival in a population-based study Cancer Res 62 3052 3057