Randomized placebo-controlled trial of pantoprazole for daytime sleepiness in GERD and obstructive sleep disordered breathing

Otolaryngology - Head and Neck Surgery

Volumn 139, Issue 2, 2008, Pages 286-290

  Suurna, Maria V ^a   Welge, Jeff ^b   Surdulescu, Victoria ^a   Kushner, Jonathan ^a   Steward, David L ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF CINCINNATI   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PANTOPRAZOLE; PLACEBO;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DAYTIME SOMNOLENCE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; FEMALE; GASTROESOPHAGEAL REFLUX; HUMAN; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; REACTION TIME; SLEEP APNEA SYNDROME;

2-PYRIDINYLMETHYLSULFINYLBENZIMIDAZOLES; ANTI-ULCER AGENTS; AROUSAL; CROSS-OVER STUDIES; DISORDERS OF EXCESSIVE SOMNOLENCE; DOUBLE-BLIND METHOD; FEMALE; GASTROESOPHAGEAL REFLUX; HUMANS; MALE; MIDDLE AGED; PLACEBOS; QUALITY OF LIFE; SLEEP APNEA SYNDROMES; TREATMENT OUTCOME; WAKEFULNESS;

EID: 47549099960     PISSN: 01945998     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.otohns.2008.03.012     Document Type: Article

References (15)

1. Young T., Blustein J., Finn L., et al. Sleep-disordered breathing and motor vehicle accidents in a population-based sample of employed adults. Sleep 20 8 (1997) 608-613
2. Teran-Santos J., Jimenez-Gomez A., and Cordero-Guevara J. The association between sleep apnea and the risk of traffic accidents. Cooperative Group Burgos-Santander. N Engl J Med 340 11 (1999) 847-851
3. Guda N., Partington S., and Vakil N. Symptomatic gastro-oesophageal reflux, arousals and sleep quality in patients undergoing polysomnography for possible obstructive sleep apnoea. Aliment Pharmacol Ther 20 10 (2004) 1153-1159
4. Young T., Palta M., Dempsey J., et al. The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med 328 17 (1993) 1230-1235
5. Locke III G.R., Talley N.J., Fett S.L., et al. Prevalence and clinical spectrum of gastroesophageal reflux: a population-based study in Olmsted County, Minnesota. Gastroenterology 112 5 (1997) 1448-1456
6. Janson C., Gislason T., De Backer W., et al. Daytime sleepiness, snoring and gastro-oesophageal reflux amongst young adults in three European countries. J Intern Med 237 3 (1995) 277-285
7. Freidin N., Fisher M.J., Taylor W., et al. Sleep and nocturnal acid reflux in normal subjects and patients with reflux oesophagitis. Gut 32 11 (1991) 1275-1279
8. Penzel T., Becker H.F., Brandenburg U., et al. Arousal in patients with gastro-oesophageal reflux and sleep apnoea. Eur Respir J 14 6 (1999) 1266-1270
9. Senior B.A., Khan M., Schwimmer C., Rosenthal L., et al. Gastroesophageal reflux and obstructive sleep apnea. Laryngoscope 111 12 (2001) 2144-2146
10. Bortolotti M., Gentilini L., Morselli C., et al. Obstructive sleep apnoea is improved by a prolonged treatment of gastrooesophageal reflux with omeprazole. Dig Liver Dis 38 2 (2006) 78-81
11. Steward D.L. Pantoprazole for sleepiness associated with acid reflux and obstructive sleep disordered breathing. Laryngoscope 114 9 (2004) 1525-1528
12. Altman D.G., Schulz K.F., Moher D., et al. The revised CONSORT statement for reporting randomized trials: explanation and elaboration. Ann Intern Med 134 (2001) 663-694
13. Johns M.W. Daytime sleepiness, snoring, and obstructive sleep apnea: the Epworth Sleepiness Scale. Chest 103 1 (1993) 30-36
14. Weaver T.E., Laizner A.M., Evans L.K., et al. An instrument to measure functional status outcomes for disorders of excessive sleepiness. Sleep 20 10 (1997) 835-843
15. Jewett M.E., Dijk D.J., Kronauer R.E., et al. Dose-response relationship between sleep duration and human psychomotor vigilance and subjective alertness. Sleep 22 2 (1999) 171-179