Structure of three class I human alcohol dehydrogenases complexed with isoenzyme specific formamide inhibitors

Biochemistry

Volumn 43, Issue 39, 2004, Pages 12555-12562

  Gibbons, Brian J ^a   Hurley, Thomas D ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOLS; ALDEHYDES; HYDROPHOBICITY; MOLECULAR STRUCTURE; SUBSTRATES;

ACTIVE SITES; ALCOHOL DEHYDRGENASES; HUMAN ALCOHOL; ISOENZYMES;

ENZYMES;

ALANINE; ALCOHOL DEHYDROGENASE; ALDEHYDE DERIVATIVE; BENZENE DERIVATIVE; FORMAMIDE DERIVATIVE; HYDROXYL GROUP; ISOENZYME; LEUCINE; N 1 METHYLHEPTYLFORMAMIDE; N BENZYLFORMAMIDE; N CYCLOPENTYL N CYCLOBUTYLFORMAMIDE; N HEPTYLFORMAMIDE; PHENYLALANINE; SERINE; THREONINE; UNCLASSIFIED DRUG; VALINE; ZINC;

ARTICLE; CATALYSIS; COMPLEX FORMATION; ENANTIOMER; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; PRIORITY JOURNAL; STEREOCHEMISTRY; X RAY CRYSTALLOGRAPHY;

ALCOHOL DEHYDROGENASE; AMINO ACID SUBSTITUTION; BINDING SITES; CATALYSIS; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; FORMAMIDES; HUMANS; ISOENZYMES; PROTEIN STRUCTURE, SECONDARY; SUBSTRATE SPECIFICITY;

EID: 4744349653     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0489107     Document Type: Article

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