Formation of hydrogen-bonded complexes between bile acids and lidocaine in the lidocaine transfer from an aqueous phase to chloroform

European Journal of Pharmaceutical Sciences

Volumn 34, Issue 4-5, 2008, Pages 281-292

  Poša, Mihalj ^a   Guzsvány, Valeria ^b   Csanádi, János ^b   Kevrešan, Slavko ^c   Kuhajda, Ksenija ^b  

^a UNIVERSITY OF NOVI SAD   (Serbia)

^b UNIVERSITY OF NOVI SAD   (Serbia)

^c Horticulture and Landscape Architecture   (Serbia)

Author keywords

Bile acids; Hydrogen bonded complex; Lidocaine

Indexed keywords

12 MONOKETODEOXYCHOLIC ACID; 3,12 DIKETODEOXYCHOLIC ACID; 3,7,12 TRIKETOCHOLIC ACID; 3,7,12 TRIOXO 5BETA CHOLANOIC ACID METHYL ESTER; 3ALPHA ACETOXY 12ALPHA HYDROXY 7 OXO 5BETA CHOLANOIC ACID METHYL ESTER; 3ALPHA ACETOXY 7,12 DIKETO 5BETA CHOLANOIC ACID METHYL ESTER; 7 MONOKETOCHENODEOXYCHOLIC ACID; 7 MONOKETOCHOLIC ACID; ACETONE; AMPHOPHILE; BILE ACID; CHENODEOXYCHOLIC ACID; CHLOROFORM; HYDROXYL GROUP; KETONE DERIVATIVE; LIDOCAINE; METHANOL;

ANALGESIC ACTIVITY; AQUEOUS SOLUTION; ARTICLE; CELL MEMBRANE TRANSPORT; COMPLEX FORMATION; DRUG BINDING; EQUILIBRIUM CONSTANT; HYDROGEN BOND; MULTIPLE LINEAR REGRESSION ANALYSIS; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; STATISTICAL MODEL;

ANESTHETICS, LOCAL; BILE ACIDS AND SALTS; CHLOROFORM; HYDROGEN BONDING; KINETICS; LIDOCAINE; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; MOLECULAR STRUCTURE; SOLUBILITY; SOLVENTS; STRUCTURE-ACTIVITY RELATIONSHIP; WATER;

EID: 47349118605     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2008.04.011     Document Type: Article

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