Aymptomatic CMV viremia is associated with increased levels of serium amyloid A in patients with advanced HIV-infection

European Journal of Medical Research

Volumn 13, Issue 6, 2008, Pages 304-308

  Steininger, Christoph ^a   Graninger, W ^a   Zoufaly, A ^b   Zollner B ^b   Feucht, H H ^b   Kundi, M ^a   Stahmer, I ^c   Stellbrink, H J ^b   van Lunzen, J ^b  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^c LEIBNIZ INSTITUTE FOR EXPERIMENTAL VIROLOGY   (Germany)

Author keywords

Acute phase proteins; AIDS; Cytomegalovirus; Immunodeficiency; Serum amyloid A; Viremia

Indexed keywords

ACUTE PHASE PROTEIN; AMYLOID A PROTEIN; C REACTIVE PROTEIN; FIBRONECTIN; HAPTOGLOBIN; INTERLEUKIN 6; LIPOPOLYSACCHARIDE BINDING PROTEIN; VIRUS DNA;

ACUTE PHASE RESPONSE; ADULT; ARTICLE; BLOOD SAMPLING; CD4 LYMPHOCYTE COUNT; CLINICAL ARTICLE; CYTOMEGALOVIRUS INFECTION; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFLAMMATION; MALE; POLYMERASE CHAIN REACTION; PROTEIN BLOOD LEVEL; RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY AND SPECIFICITY; VIREMIA;

ADULT; CD4-POSITIVE T-LYMPHOCYTES; COHORT STUDIES; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; FEMALE; HIV INFECTIONS; HUMANS; INFLAMMATION; MALE; MIDDLE AGED; MODELS, BIOLOGICAL; PROSPECTIVE STUDIES; ROC CURVE; SERUM AMYLOID A PROTEIN;

EID: 47349113120     PISSN: 09492321     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Steininger C, Puchhammer-Stockl E, Popow-Kraupp T. Cytomegalovirus disease in the era of highly active anti-retroviral therapy (HAART). J Clin Virol. 2006 May 1; 37(1): 1-9
2. Mocroft A, Katlama C, Johnson AM, et al. AIDS across Europe, 1994-98: the EuroSIDA study. Lancet. 2000 Jul 22; 356(9226): 291-6
3. Palella FJ, Jr., Delaney KM, Moorman AC, et al. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators. N Engl J Med. 1998 Mar 26; 338(13): 853-60
4. Hengel H, Brune W, Koszinowski UH. Immune evasion by cytomegalovirus - survival strategies of a highly adapted opportunist. Trends Microbiol. 1998 May; 6(5): 190-7
5. Webster A, Lee CA, Cook DG, et al. Cytomegalovirus infection and progression towards AIDS in haemophiliacs with human immunodeficiency virus infection. Lancet. 1989 Jul 8; 2(8654): 63-6
6. Sabin CA, Devereux HL, Clewley G, et al. Cytomegalovirus seropositivity and human immunodeficiency virus type 1 RNA levels in individuals with hemophilia. J Infect Dis. 2000 May; 181(5): 1800-3
7. Robain M, Boufassa F, Hubert JB, Persoz A, Burgard M, Meyer L. Cytomegalovirus seroconversion as a cofactor for progression to AIDS. AIDS. 2001 Jan 26; 15(2): 251-6
8. Nokta MA, Holland F, De G, V, et al. Cytomegalovirus (CMV) polymerase chain reaction profiles in individuals with advanced human immunodeficiency virus infection: relationship to CMV disease. J Infect Dis. 2002 Jun 15; 185(12): 1717-22
9. Spector SA, Wong R, Hsia K, Pilcher M, Stempien MJ. Plasma cytomegalovirus (CMV) DNA load predicts CMV disease and survival in AIDS patients. J Clin Invest. 1998 Jan 15; 101(2): 497-502
10. Deayton JR, Sabin CA, Johnson MA, Emery VC, Wilson P, Griffiths PD. Importance of cytomegalovirus viraemia in risk of disease progression and death in HIV-infected patients receiving highly active antiretroviral therapy. Lancet. 2004 Jun 26; 363(9427): 2116-21
11. Gerard L, Leport C, Flandre P, et al. Cytomegalovirus (CMV) viremia and the CD4+ lymphocyte count as predictors of CMV disease in patients infected with human immunodeficiency virus. Clin Infect Dis. 1997 May; 24(5): 836-40
12. Kaplan JE, Masur H, Holmes KK. Guidelines for preventing opportunistic infections among HIV-infected persons - 2002. Recommendations of the U.S. Public Health Service and the Infectious Diseases Society of America. MMWR Recomm Rep. 2002 Jun 14; 51(RR-8): 1-52
13. Stroud M, Swindell B, Bernard GR. Cellular and humoral mediators of sepsis syndrome. Crit Care Nurs Clin North Am. 1990 Jun; 2(2): 151-60
14. Presterl E, Staudinger T, Pettermann M, et al. Cytokine profile and correlation to the APACHE III and MPM II scores in patients with sepsis. Am J Respir Crit Care Med. 1997 Sep; 156(3 Pt 1): 825-32
15. Simon L, Gauvin F, Amre DK, Saint-Louis P, Lacroix J. Serum procalcitonin and C-reactive protein levels as markers of bacterial infection: a systematic review and meta-analysis. Clin Infect Dis. 2004 Jul 15; 39(2): 206-17
16. Verkerk MS, Visseren FL, Paul BK, Diepersloot RJ. Acute-phase response of human hepatocytes after infection with Chlamydia pneumoniae and cytomegalovirus. Eur J Clin Invest. 2003 Aug; 33(8): 720-5
17. Birgegard G, Hallgren R, Killander A, Stromberg A, Venge P, Wide L. Serum ferritin during infection. A longitudinal study. Scand J Haematol. 1978 Oct; 21(4): 333-40
18. Miwata H, Yamada T, Okada M, Kudo T, Kimura H, Morishima T. Serum amyloid A protein in acute viral infections. Arch Dis Child. 1993 Feb; 68(2): 210-4
19. Whicher JT, Chambers RE, Higginson J, Nashef L, Higgins PG. Acute phase response of serum amyloid A protein and C reactive protein to the common cold and influenza. J Clin Pathol. 1985 Mar; 38(3): 312-6
20. Dodt KK, Jacobsen PH, Hofmann B, et al. Development of cytomegalovirus (CMV) disease may be predicted in HIV-infected patients by CMV polymerase chain reaction and the antigenemia test. AIDS. 1997 Mar; 11(3): F21-F28
21. Nakayama T, Sonoda S, Urano T, Yamada T, Okada M. Monitoring both serum amyloid protein A and C-reactive protein as inflammatory markers in infectious diseases. Clin Chem. 1993 Feb; 39(2): 293-7
22. Lannergard A, Larsson A, Kragsbjerg P, Friman G. Correlations between serum amyloid A protein and C-reactive protein in infectious diseases. Scand J Clin Lab Invest. 2003; 63(4): 267-72
23. Malle E, De Beer FC. Human serum amyloid A (SAA) protein: a prominent acute-phase reactant for clinical practice. Eur J Clin Invest. 1996 Jun; 26(6): 427-35