Regional citrate anticoagulation for hemodialysis: Calcium-free vs. calcium containing dialysate - A randomized trial

International Journal of Artificial Organs

Volumn 31, Issue 5, 2008, Pages 418-424

  Buturovic Ponikvar, Jadranka ^a   Cerne, S ^a   Gubensek, J ^a   Ponikvar, R ^a  

^a UNIVERSITY MEDICAL CENTRE LJUBLJANA   (Slovenia)

Author keywords

Anticoagulation; Citrate; Hemodialysis; Metabolic alkalosis; Regional citrate anti coagulation

Indexed keywords

CALCIUM; CHLORINE COMPOUNDS; HEMODIALYZERS; PATIENT MONITORING; PATIENT TREATMENT; SODIUM COMPOUNDS;

ANTI-COAGULATION; BUBBLE-TRAP; CITRATE; CLINICAL STUDY; DIALYSATES; HAEMODIALYSIS; METABOLIC ALKALOSIS; RANDOMIZED TRIAL; REGIONAL CITRATE ANTI-COAGULATION;

DIALYSIS;

BICARBONATE; CALCIUM; CITRATE TRISODIUM; HEMODIALYSIS FLUID; HEPARIN;

ANTICOAGULATION; ARTERY THROMBOSIS; ARTICLE; ARTIFICIAL KIDNEY; BLEEDING TENDENCY; BLOOD CLOTTING; CLINICAL ARTICLE; CLINICAL TRIAL; CONCENTRATION RESPONSE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; HEMODIALYSIS; HEPARIN INDUCED THROMBOCYTOPENIA; HUMAN; INTERMETHOD COMPARISON; KIDNEY DISEASE; RANDOMIZED CONTROLLED TRIAL; VEIN THROMBOSIS;

EID: 47249144696     PISSN: 03913988     EISSN: None     Source Type: Journal    
DOI: 10.1177/039139880803100507     Document Type: Article

References (13)

1. Hofbauer R, Moser D, Frass M, Oberbauer R, Kaye AD, Wagner O, Kapiotis S, Druml W. Effect of anticoagulation on blood membrane interactions during hemodialysis. Kidney Int 1999; 56: 1578-83.
2. Bos JC, Grooteman MP, van Houte AJ, Schoorl M, van Limbeek J, Nube MJ. Low polymorphonuclear cell degranulation during citrate anticoagulation: a comparison between citrate and heparin dialysis. Nephrol Dial Transplant 1997; 12: 1387-93.
3. Gritters M, Grooteman MP, Schoorl M, Bartels PC, Scheffer PG, Teerlink T, Schalkwijk CG, Spreeuwenberg M, Nube MJ. Citrate anticoagulation abolishes degranulation of polymorphonuclear cells and platelets and reduces oxidative stress during haemodialysis. Nephrol Dial Transplant 2006; 21: 153-9.
4. Gabutti L, Ferrari N, Mombelli G, Keller F, Marone C. The favorable effect of regional citrate anticoagulation on interleukin-1beta release is dissociated from both coagulation and complement activation. J Nephrol 2004; 17: 819-25.
5. Evenepoel P, Maes B, Vanwalleghem J, Kuypers D, Messiaen T, Vanrenterghem Y. Regional citrate anticoagulation for hemodialysis using a conventional calcium-containing dialysate. Am J Kidney Dis 2002; 39: 315-23.
6. Apsner R, Buchmayer H, Gruber D, Sunder-Plassmann G. Citrate for long-term hemodialysis: prospective study of 1,009 consecutive high-flux treatments in 59 patients. Am J Kidney Dis 2005; 45: 557-64.
7. Janssen MJ, Huijgens PC, Bouman AA, Oe PL, Donker AJ, van der Meulen J. Citrate versus heparin anticoagulation in chronic haemodialysis patients. Nephrol Dial Transplant 1993; 8: 1228-33.
8. Buturovic-Ponikvar J, Gubensek J, Škofic N, Ponikvar R. Regional citrate anticoagulation for predilutional on-line hemofiltration [abstract]. Blood Purif 2006; 24: 260.
9. Von Brecht JH, Flanigan MJ, Freeman RM, Lim VS. Regional anticoagulation: hemodialysis with hypertonic trisodium citrate. Am J Kidney Dis 1986; 8: 196-201.
10. Evenepoel P, Dejagere T, Verhamme P, Claes K, Kuypers D, Bammens B, Vanrenterghem Y. Heparin-coated polyacrylonitrile membrane versus regional citrate anticoagulation: a prospective randomized study of 2 anticoagulant strategies in patients at risk of bleeding. Am J Kidney Dis 2007; 49: 642-9.
11. Buturovic-Ponikvar J, Gubensek J, Ponikvar R. Citrate anti-coagulation for postdilutional online hemodiafiltration with calcium-containing dialysate and infusate: Significant clotting in the venous bubble trap. Int J Artif Organs 2008; 31: 323-8.
12. Ridel C, Mercadal L, Bene B, Hamani A, Deray G, Petitclerc T. Regional citrate anticoagulation during hemodialysis: a simplified procedure using duocart biofiltration. Blood Purif 2005; 23: 473-80.
13. Ahmad S, Callan R, Cole JJ, Blagg CR. Dialysate made from dry chemicals using citric acid increase dialysis dose. Am J Kidney Dis 2000; 35: 493-9.