Citrate anticoagulation for postdilutional online hemodiafiltration with calcium-containing dialysate and infusate: Significant clotting in the venous bubble trap

International Journal of Artificial Organs

Volumn 31, Issue 4, 2008, Pages 323-328

  Buturovic Ponikvar, Jadranka ^a   Gubensek, J ^a   Ponikvar, R ^a  

^a UNIVERSITY MEDICAL CENTRE LJUBLJANA   (Slovenia)

Author keywords

Citrate; Hemodiafiltration; Regional citrate anticoagulation

Indexed keywords

ANTI-COAGULATION; ANTITHROMBOTIC; BUBBLE-TRAP; CITRATE; CLINICAL STUDY; DIALYSATES; END-STAGE RENAL DISEASE PATIENTS; HEMODIAFILTRATION; PROSPECTIVES; REGIONAL CITRATE ANTICOAGULATION;

CALCIUM CHLORIDE;

CALCIUM CHLORIDE; CITRATE TRISODIUM; HEPARIN;

ADULT; AGED; ANTICOAGULATION; ARTICLE; BLOOD CLOTTING DISORDER; BLOOD FLOW; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIALYSATE; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG SAFETY; DRUG SUBSTITUTION; DRUG WITHDRAWAL; FEMALE; HEMODIAFILTRATION; HUMAN; INCIDENCE; KIDNEY FAILURE; MALE; METABOLIC DISORDER; ONLINE SYSTEM; SCORING SYSTEM; TREATMENT DURATION;

EID: 45949086888     PISSN: 03913988     EISSN: None     Source Type: Journal    
DOI: 10.1177/039139880803100408     Document Type: Article

References (19)

1. Hofbauer R, Moser D, Frass M, Oberbauer R, Kaye AD, Wagner O, Kapiotis S, Druml W. Effect of anticoagulation on blood membrane interactions during hemodialysis. Kidney Int 1999; 56: 1578-83.
2. Bos JC, Grooteman MP, Van Houte AJ, Schoorl M, van Limbeek J, Nube MJ. Low polymorphonuclear cell degranulation during citrate anticoagulation: a comparison between citrate and heparin dialysis. Nephrol Dial Transplant 1997; 12: 1387-93.
3. Gritters M, Grooteman MP, Schoorl M, Schoorl M, Bartels PC, Scheffer PG, Teerlink T, Schalkwijk CG, Spreeuwenberg M, Nubé MJ. Citrate anticoagulation abolishes degranulation of polymorphonuclear cells and platelets and reduces oxidative stress during haemodialysis. Nephrol Dial Transplant 2006; 21: 153-9.
4. Canaud B, Bosc JY, Leray H, Stec F Argiles; A, Leblanc M, Mion C. On-line haemodiafiltration: state of the art. Nephrol Dial Transplant 1998; 13 (Suppl 5): S3-11.
5. Canaud B, Bragg-Gresham JL, Marshall MR, Desmeules S, Gillespie BW, Depner T, Klassen P, Port FK. Mortality risk for patients receiving hemodiafiltration versus hemodialysis: european results from the DOPPS. Kidney Int 2006; 69: 2087-93.
6. von Brecht JH, Flanigan MJ, Freeman RM, Lim VS. Regional anticoagulation: hemodialysis with hypertonic trisodium citrate. Am J Kidney Dis 1986; 8: 196-201.
7. Evenepoel P, Maes B, Vanwalleghem J, Kuypers D, Messiaen T, Vanrenterghem Y. Regional citrate anticoagulation for hemodialysis using a conventional calcium-containing dialysate. Am J Kidney Dis 2002; 39: 315-23.
8. Buturovic-Ponikvar J, Gubensek J, Skofic N, Ponikvar R. Regional citrate anticoagulation for predilutional on-line hemofiltration [abstract]. Blood Purif 2006; 24:260.
9. Buturovic-Ponikvar J, Gubensek J, Ponikvar R. Citrate anticoagulation for single-needle hemodialysis: safety and efficacy. Ther Apher Dial 2005; 9: 237-40.
10. Buturovic-Ponikvar J, Pernat AM, Ponikvar R. Citrate anticoagulation during plasma exchange in a patient with thrombotic thrombocytopenic purpura: short heparin-free hemodialysis helps to attenuate citrate load. Ther Apher Dial 2005; 9: 258-61.
11. Buturovic Ponikvar J, Catak S, Benedik M, Varl J, Knap B, Marn Pernat A, Kandus A, Gucek A, Premru V, Malovrh M, Gubensek J, Skofic N, Gaber L, Bren AF, Ponikvar R. Regional citrate anti-coagulation during hemodialysis: our experience [abstract]. Ther Apher Dial 2005; 9: 87.
12. Meier-Kriesche HU, Gitomer J, Finkel K, DuBose T. Increased total to ionized calcium ratio during continuous venovenous hemodialysis with regional citrate anticoagulation. Crit Care Med 2001;29:748-52.
13. Warty VS, Busch RP, Virji MA. A kit for citrate in foodstuffs adapted for assay of serum and urine. Clin Chem 1984; 30: 1231-3.
14. Pinnick RV, Wiegmann TB, Diederich DA. Regional citrate anti-coagulation for hemodialysis in the patient at high risk for bleeding. N Engl J Med 1983; 308: 258-61.
15. Lohr JW, Slusher S, Diederich D. Safety of regional citrate hemodialysis in acute renal failure. Am J Kidney Dis 1989; 13: 104-7.
16. Apsner R, Buchmayer H, Lang T, Unver B, Speiser W, Sunder-Plassmann G, Horl WH. Simplified citrate anticoagulation for high-flux hemodialysis. Am J Kidney Dis 2001; 38: 979-87.
17. Calatzis A, Toepfer M, Schramm W, Spannagl M, Schiffl H. Citrate anticoagulation for extracorporeal circuits: effects on whole blood coagulation activation and clot formation. Nephron 2001; 89: 233-6.
18. Klingel R, Schaefer M, Schwarting A, Himmelsbach F, Altes U, Uhlenbusch-Korwer I, Hafner G. Comparative analysis of pro-coagulatory activity of haemodialysis, haemofiltration and haemodiafiltration with a polysulfone membrane (APS) and with different modes of enoxaparin anticoagulation. Nephrol Dial Transplant 2004; 19:164-70.
19. Buturovic J, Gubensek J, Cerne D, Ponikvar R. Standard citrate vs. sequential citrate/anticoagulant-free anticoagulation during hemodialysis: a randomized trial. Artif Organs 2008; 31: 77-81.