메뉴 건너뛰기




Volumn 4, Issue 3, 2008, Pages 427-432

Fibroblast independency in tumors: Implications in cancer therapy

Author keywords

Autonomy; Fibroblasts; Stroma; Therapy

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; DOXORUBICIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN P53; PROTEIN TYROSINE KINASE INHIBITOR;

EID: 47249136922     PISSN: 14796694     EISSN: 17448301     Source Type: Journal    
DOI: 10.2217/14796694.4.3.427     Document Type: Review
Times cited : (10)

References (21)
  • 2
    • 0036843937 scopus 로고    scopus 로고
    • Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomas
    • Kurose K, Gilley K, Matsumoto S, Watson PH, Zhou XP, Eng C: Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomas. Nat. Cenet. 32, 355-357 (2002).
    • (2002) Nat. Cenet , vol.32 , pp. 355-357
    • Kurose, K.1    Gilley, K.2    Matsumoto, S.3    Watson, P.H.4    Zhou, X.P.5    Eng, C.6
  • 3
    • 5644294349 scopus 로고    scopus 로고
    • Combined total genome loss of heterozygosity scan of breast cancer stroma and epithelium reveals multiplicity of stromal targets
    • Fukino K, Shen L, Matsumoto S, Morrison CD, Mutter GL, Eng C: Combined total genome loss of heterozygosity scan of breast cancer stroma and epithelium reveals multiplicity of stromal targets. Cancer Res. 64, 7231-7236 (2004).
    • (2004) Cancer Res , vol.64 , pp. 7231-7236
    • Fukino, K.1    Shen, L.2    Matsumoto, S.3    Morrison, C.D.4    Mutter, G.L.5    Eng, C.6
  • 4
    • 0342264492 scopus 로고    scopus 로고
    • Concurrent and independent genetic alterations in the stromal and epithelial cells of mammary carcinoma: Implications for tumorigenesis
    • Moinfar F, Man YC, Arnould L, Bratthauer GL, Ratschek M, Tavassoli FA: Concurrent and independent genetic alterations in the stromal and epithelial cells of mammary carcinoma: Implications for tumorigenesis. Cancer Res. 60, 2562-2566 (2000).
    • (2000) Cancer Res , vol.60 , pp. 2562-2566
    • Moinfar, F.1    Man, Y.C.2    Arnould, L.3    Bratthauer, G.L.4    Ratschek, M.5    Tavassoli, F.A.6
  • 5
    • 37349101054 scopus 로고    scopus 로고
    • Breast-cancer stromal cells with TP53 mutations and nodal metastases
    • Patocs A, Zhang L, Xu Y et al.: Breast-cancer stromal cells with TP53 mutations and nodal metastases. N. Engl. J. Med. 357, 2543-2551 (2007).
    • (2007) N. Engl. J. Med , vol.357 , pp. 2543-2551
    • Patocs, A.1    Zhang, L.2    Xu, Y.3
  • 6
    • 1642334157 scopus 로고    scopus 로고
    • Tumour-derived TGF-β1 modulates myofibroblast differentiation and promotes HGF/SF-dependent invasion of squamous carcinoma cells
    • Lewis MP, Lygoe KA, Nystrom ML et al.: Tumour-derived TGF-β1 modulates myofibroblast differentiation and promotes HGF/SF-dependent invasion of squamous carcinoma cells. Br. J. Cancer 90, 822-832 (2004).
    • (2004) Br. J. Cancer , vol.90 , pp. 822-832
    • Lewis, M.P.1    Lygoe, K.A.2    Nystrom, M.L.3
  • 7
    • 34249295225 scopus 로고    scopus 로고
    • Cross-talk between paracrine-acting cytokine and chemokine pathways promotes malignancy in benign human prostatic epithelium
    • Ao M, Franco OE, Park D, Raman D, Williams K, Hayward SW. Cross-talk between paracrine-acting cytokine and chemokine pathways promotes malignancy in benign human prostatic epithelium. Cancer Res. 67, 4244-4253 (2007).
    • (2007) Cancer Res , vol.67 , pp. 4244-4253
    • Ao, M.1    Franco, O.E.2    Park, D.3    Raman, D.4    Williams, K.5    Hayward, S.W.6
  • 8
    • 5444248307 scopus 로고    scopus 로고
    • Tenascin-C and SF/HGF produced by myofibroblasts in vitro provide convergent pro-invasive signals to human colon cancer cells through RhoA and Rac
    • De Wever O, Nguyen QD, Van Hoorde L et al.: Tenascin-C and SF/HGF produced by myofibroblasts in vitro provide convergent pro-invasive signals to human colon cancer cells through RhoA and Rac. FASEB J. 18, 1016-1018 (2004).
    • (2004) FASEB J , vol.18 , pp. 1016-1018
    • De Wever, O.1    Nguyen, Q.D.2    Van Hoorde, L.3
  • 9
    • 0036995757 scopus 로고    scopus 로고
    • Matrix, metalloproteinases in tumor-host cell communication
    • Lynch CC, Matrisian LM: Matrix, metalloproteinases in tumor-host cell communication. Differentiation 70, 561-573 (2002).
    • (2002) Differentiation , vol.70 , pp. 561-573
    • Lynch, C.C.1    Matrisian, L.M.2
  • 10
    • 1842687362 scopus 로고    scopus 로고
    • Reconstruction of functionally normal and malignant human breast tissues in mice
    • Kuperwasser C, Chavarria T, Wu M et al.: Reconstruction of functionally normal and malignant human breast tissues in mice. Proc. Natl Acad. Sci. USA 101, 4966-4971 (2004).
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 4966-4971
    • Kuperwasser, C.1    Chavarria, T.2    Wu, M.3
  • 12
    • 0842288323 scopus 로고    scopus 로고
    • TGF-β signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia
    • Bhowmick NA, Chytil A, Plieth D et al.: TGF-β signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia. Science 303, 848-851 (2004).
    • (2004) Science , vol.303 , pp. 848-851
    • Bhowmick, N.A.1    Chytil, A.2    Plieth, D.3
  • 13
    • 18844428327 scopus 로고    scopus 로고
    • Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
    • Orimo A, Gupta PB, Sgroi DC et al.: Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell 121, 335-348 (2005).
    • (2005) Cell , vol.121 , pp. 335-348
    • Orimo, A.1    Gupta, P.B.2    Sgroi, D.C.3
  • 14
    • 0035835829 scopus 로고    scopus 로고
    • Heterotypic signaling between epithelial tumor cells and fibroblasts in carcinoma formation
    • Elenbaas B, Weinberg RA: Heterotypic signaling between epithelial tumor cells and fibroblasts in carcinoma formation. Exp. Cell Res. 264, 169-184 (2001).
    • (2001) Exp. Cell Res , vol.264 , pp. 169-184
    • Elenbaas, B.1    Weinberg, R.A.2
  • 15
    • 0033215242 scopus 로고    scopus 로고
    • Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium
    • Olumi AF, Grossfeld GD, Hayward SW, Carroll PR, Tisty TD, Cunha GR: Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium. Cancer Res. 59, 5002-5011 (1999).
    • (1999) Cancer Res , vol.59 , pp. 5002-5011
    • Olumi, A.F.1    Grossfeld, G.D.2    Hayward, S.W.3    Carroll, P.R.4    Tisty, T.D.5    Cunha, G.R.6
  • 16
    • 0042415425 scopus 로고    scopus 로고
    • Role of the stromal microenvironment in carcinogenesis of the prostate
    • Cunha GR, Hayward SW, Wang YZ, Ficke WA: Role of the stromal microenvironment in carcinogenesis of the prostate. Int. J. Cancer 107, 1-10 (2003).
    • (2003) Int. J. Cancer , vol.107 , pp. 1-10
    • Cunha, G.R.1    Hayward, S.W.2    Wang, Y.Z.3    Ficke, W.A.4
  • 17
    • 0032477806 scopus 로고    scopus 로고
    • Tumorigenic conversion of immortal human keratinocytes through stromal cell activation
    • Skobe M, Fusenig NE: Tumorigenic conversion of immortal human keratinocytes through stromal cell activation. Proc. Natl Acad. Sci. USA 95, 1050-1055 (1998).
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 1050-1055
    • Skobe, M.1    Fusenig, N.E.2
  • 18
    • 47049117155 scopus 로고    scopus 로고
    • p53 mutations in stromal fibroblasts sensitize tumors against chemotherapy
    • In press
    • Lafkas D, Trimis G, Papavassiliou AG, Kiaris H: p53 mutations in stromal fibroblasts sensitize tumors against chemotherapy. Int. J. Cancer (2008) (In press).
    • (2008) Int. J. Cancer
    • Lafkas, D.1    Trimis, G.2    Papavassiliou, A.G.3    Kiaris, H.4
  • 19
    • 34547111065 scopus 로고    scopus 로고
    • Involvement of an autocrine stromal cell derived factor-1/CXCR4 system on the distant metastasis of human oral squamous cell carcinoma
    • Uchida D, Onoue T, Tomizuka Y et al.: Involvement of an autocrine stromal cell derived factor-1/CXCR4 system on the distant metastasis of human oral squamous cell carcinoma. Mol. Cancer Res. 5, 685-694 (2007).
    • (2007) Mol. Cancer Res , vol.5 , pp. 685-694
    • Uchida, D.1    Onoue, T.2    Tomizuka, Y.3
  • 20
    • 33751319000 scopus 로고    scopus 로고
    • Stromal derived factor-1 (SDF-1/CXCL12) and CXCR4 in renal cell carcinoma metastasis
    • Pan J, Mestas J, Burdick MD et al.: Stromal derived factor-1 (SDF-1/CXCL12) and CXCR4 in renal cell carcinoma metastasis. Mol. Cancer 5, 56 (2006).
    • (2006) Mol. Cancer , vol.5 , pp. 56
    • Pan, J.1    Mestas, J.2    Burdick, M.D.3
  • 21
    • 34248363901 scopus 로고    scopus 로고
    • CXCR4 expression is associated with pelvic lymph node metastasis in cervical adenocarcinoma
    • Yang YC, Lee ZY, Wu CC, Chen TC, Chang CL, Chen CP: CXCR4 expression is associated with pelvic lymph node metastasis in cervical adenocarcinoma. Int. Gynecol. Cancer 17, 676-686 (2007).
    • (2007) Int. Gynecol. Cancer , vol.17 , pp. 676-686
    • Yang, Y.C.1    Lee, Z.Y.2    Wu, C.C.3    Chen, T.C.4    Chang, C.L.5    Chen, C.P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.