Paradoxical elevated thiopurine s-methyltransferase activity after pancytopenia during azathioprine therapy: Potential influence of red blood cell age

Therapeutic Drug Monitoring

Volumn 30, Issue 3, 2008, Pages 390-393

  De Boer, Nanne K H ^a,d   Van Bodegraven, Adriaan A ^a   De Graaf, Peer ^b   Van Der Hulst, Rene W M ^c   Zoetekouw, Lida ^b   Van Kuilenburg, André B P ^b  

^a Gastroenterology and Hepatology   (Netherlands)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

^c Infection and Immunology   (Netherlands)

^d VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

Azathioprine; Bone marrow depression; Crohn's disease; Cytomegalovirus; Red blood cell age; TPMT

Indexed keywords

AMINOGLYCOSIDE; AMINOPENICILLIN; AZATHIOPRINE; CORTICOSTEROID; MESALAZINE; THIOPURINE METHYLTRANSFERASE; IMMUNOSUPPRESSIVE AGENT; METHYLTRANSFERASE;

ABDOMINAL PAIN; ADOLESCENT; ARTICLE; BLOOD CULTURE; BONE MARROW DEPRESSION; CASE REPORT; COLON CROHN DISEASE; COMPUTER ASSISTED TOMOGRAPHY; CONVALESCENCE; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTION; DIARRHEA; ENTERITIS; ENZYME ACTIVITY; ERYTHROCYTE; ERYTHROCYTE LIFESPAN; ERYTHROPOIESIS; FEMALE; HEMICOLECTOMY; HUMAN; ILEOCECAL VALVE; ILEUM; LABORATORY TEST; LAPAROTOMY; PANCYTOPENIA; PHENOTYPE; PHYSICAL EXAMINATION; PRIORITY JOURNAL; REMISSION; SEROLOGY; SIGMOID; THORAX RADIOGRAPHY; VIRUS INFECTION; VIRUS PNEUMONIA; BLOOD; BLOOD CELL COUNT; CROHN DISEASE; DRUG EFFECT; ENZYMOLOGY; METABOLISM; PHYSIOLOGY;

ADOLESCENT; AZATHIOPRINE; BLOOD CELL COUNT; CROHN DISEASE; ERYTHROCYTE AGING; ERYTHROCYTES; FEMALE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; METHYLTRANSFERASES; PANCYTOPENIA;

EID: 47249126135     PISSN: 01634356     EISSN: 15363694     Source Type: Journal    
DOI: 10.1097/FTD.0b013e31816c20b3     Document Type: Article

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