New insights into the functions and N-glycan structures of factor X activator from Russell's viper venom

FEBS Journal

Volumn 275, Issue 15, 2008, Pages 3944-3958

  Chen, Hong Sen ^a   Chen, Jin Mei ^b   Lin, Chia Wei ^a   Khoo, Kay Hooi ^a,b   Tsai, Inn Ho ^a,b  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b INSTITUTE OF BIOLOGICAL CHEMISTRY   (Taiwan)

Author keywords

cDNA cloning; Factor X activator; Glycan mass spectrometry; Lewis and sialyl Lewis; Russell's viper venom

Indexed keywords

BLOOD CLOTTING FACTOR 10; BLOOD CLOTTING FACTOR 9; COMPLEMENTARY DNA; GLYCAN; GLYCOPEPTIDE; PROTEIN S; SNAKE VENOM;

AMINO ACID SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME SPECIFICITY; FAR WESTERN BLOTTING; GLYCOSYLATION; HEAVY CHAIN; LIGHT CHAIN; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN STRUCTURE; SEQUENCE ALIGNMENT; SNAKE;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CARBOHYDRATE CONFORMATION; DNA PRIMERS; ENZYME ACTIVATORS; FACTOR X; GLYCOPEPTIDES; GLYCOSYLATION; HUMANS; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; POLYSACCHARIDES; SEQUENCE HOMOLOGY, AMINO ACID; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SUBSTRATE SPECIFICITY; VIPER VENOMS;

DABOIA RUSSELLII SIAMENSIS; MACROVIPERA LEBETINA; VIPERINAE;

EID: 47249125425     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2008.06540.x     Document Type: Article

References (43)

1. Yamada D, Sekiya F Morita T (1998) Prothrombin and factor X activator activities in the venoms of Viperidae snakes. Toxicon 35, 1581 1589.
2. Kini RM (2005) The intriguing world of prothrombin activators from snake venom. Toxicon 45, 1133 1145.
3. Zhang Y, Xiong YL Bon C (1995) An activator of blood coagulation factor X from the venom of Bungarus fasciatus. Toxicon 33, 1277 1288.
4. Morita T (1998) Proteases which activate factor X. In Enzymes From Snake Venom (Bailey GS, ed pp. 179 208. Alaken, Fort Collins, CO.
5. Jackson CM Nemerson Y (1980) Blood coagulation. Annu Rev Biochem 49, 765 811.
6. Lindquist PA, Fujikawa K Davie EW (1978) Activation of bovine factor IX (Christmas factor) by factor XIa (activated plasma thromboplastin antecedent) and a protease from Russell's viper venom. J Biol Chem 253, 1902 1909.
7. Tans G Rosing J (2001) Snake venom activators of factor X: an overview. Haemostasis 31, 225 233.
8. Takeya H, Nishida S, Miyata T, Kawada S, Saisaka Y, Morita T Iwanaga S (1992) Coagulation factor X activating enzyme from Russell's viper venom (RVV-X). A novel metalloproteinase with disintegrin (platelet aggregation inhibitor)-like and C-type lectin domains. J Biol Chem 267, 14109 14117.
9. Gowda DC, Jackson CM, Hensley P Davidson EA (1994) Factor X-activating glycoprotein of Russell's viper venom. Polypeptide composition and characterization of the carbohydrate moieties. J Biol Chem 269, 10644 10650.
10. Fox JW Serrano SM (2005) Structural considerations of the snake venom metalloproteinases, key members of the M12 reprolysin family of metalloproteinases. Toxicon 45, 969 985.
11. Atoda H, Yoshida N, Ishikawa M Morita T (1994) Binding properties of the coagulation factor IX/factor X-binding protein isolated from the venom of Trimeresurus flavoviridis. Eur J Biochem 224, 703 708.
12. Takeda S, Igarashi T Mori H (2007) Crystal structure of RVV-X: an example of evolutionary gain of specificity by ADAM proteinases. FEBS Lett 581, 5859 5864.
13. Siigur E, Tonismagi K, Trummal K, Samel M, Vija H, Subbi J Siigur J (2001) Factor X activator from Vipera lebetina snake venom, molecular characterization and substrate specificity. Biochim Biophys Acta 1568, 90 98.
14. Siigur E, Aaspollu A, Trummal K, Tonismagi K, Tammiste I, Kalkkinen N Siigur J (2004) Factor X activator from Vipera lebetina venom is synthesized from different genes. Biochim Biophys Acta 1702, 41 51.
15. Gowda DC, Jackson CM, Kurzban GP, McPhie P Davidson EA (1996) Core sugar residues of the N-linked oligosaccharides of Russell's viper venom factor X-activator maintain functionally active polypeptide structure. Biochemistry 35, 5833 5837.
16. Kisiel W, Hermodson MA Davie EW (1976) Factor X activating enzyme from Russell's viper venom: isolation and characterization. Biochemistry 15, 4901 4906.
17. Masuda S, Hayashi H Araki S (1998) Two vascular apoptosis-inducing proteins from snake venom are members of the metalloprotease/disintegrin family. Eur J Biochem 253, 36 41.
18. Skogen WF, Bushong DS, Johnson AE Cox AC (1983) The role of the Gla domain in the activation of bovine coagulation factor X by the snake venom protein XCP. Biochem Biophys Res Commun 111, 14 20.
19. Mizuno H, Fujimoto Z, Atoda H Morita T (2001) Crystal structure of an anticoagulant protein in complex with the Gla domain of factor X. Proc Natl Acad Sci USA 98, 7230 7234.
20. Dahlback B (1995) The protein C anticoagulant system: inherited defects as basis for venous thrombosis. Thromb Res 77, 1 43.
21. Hackeng TM, Sere KM, Tans G Rosing J (2006) Protein S stimulates inhibition of the tissue factor pathway by tissue factor pathway inhibitor. Proc Natl Acad Sci USA 103, 3106 3111.
22. Mizuno H, Fujimoto Z, Koizumi M, Kano H, Atoda H Morita T (1997) Structure of coagulation factors IX/X-binding protein, a heterodimer of C-type lectin domains. Nat Struct Biol 4, 438 441.
23. Atoda H, Kaneko H, Mizuno H Morita T (2002) Calcium-binding analysis and molecular modeling reveal Echis coagulation factor IX/factor X-binding protein has the Ca-binding properties and Ca ion-independent folding of other C-type lectin-like proteins. FEBS Lett 531, 229 234.
24. Kishimoto M Takahashi T (2002) Molecular cloning of HR1a and HR1b, high molecular hemorrhagic factors, from Trimeresurus flavoviridis venom. Toxicon 40, 1369 1375.
25. Takeda S, Igarashi T, Mori H Araki S (2006) Crystal structures of VAP1 reveal ADAMs' MDC domain architecture and its unique C-shaped scaffold. EMBO J 25, 2388 2396.
26. Than-Than, Hutton RA, Myint-Lwin, Khin-Ei-Han, Soe-Soe, Tin-Nu-Swe, Phillips RE Warrell DA (1988) Haemostatic disturbances in patients bitten by Russell's viper (Vipera russelli siamensis) in Burma. Br J Haematol 69, 513 520.
27. Li QB, Yu QS, Huang GW, Tokeshi Y, Nakamura M, Kinjoh K Kosugi T (2000) Hemostatic disturbances observed in patients with snakebite in south China. Toxicon 38, 1355 1366.
28. Kannagi R, Izawa M, Koike T, Miyazaki K Kimura N (2004) Carbohydrate-mediated cell adhesion in cancer metastasis and angiogenesis. Cancer Sci 95, 377 384.
29. Furie B Furie BC (2004) Role of platelet P-selectin and microparticle PSGL-1 in thrombus formation. Trends Mol Med 10, 171 178.
30. Geyer A, Fitzpatrick TB, Pawelek PD, Kitzing K, Vrielink A, Ghisla S Macheroux P (2001) Structure and characterization of the glycan moiety of L-amino-acid oxidase from the Malayan pit viper Calloselasma rhodostoma. Eur J Biochem 268, 4044 4053.
31. Ande SR, Kommoju PR, Draxl S, Murkovic M, Macheroux P, Ghisla S Ferrando-May E (2006) Mechanisms of cell death induction by l-amino acid oxidase, a major component of ophidian venom. Apoptosis 11, 1439 1451.
32. x structures. Glycobiology 11, 195 208.
33. Fu Q, Satyaswaroop PG Gowda DC (1997) Tissue targeting and plasma clearance of cobra venom factor in mice. Biochem Biophys Res Commun 231, 316 320.
34. Tokunaga F, Nagasawa K, Tamura S, Miyata T, Iwanaga S Kisiel W (1988) The factor V-activating enzyme (RVV-V) from Russell's viper venom. J Biol Chem 263, 17471 17481.
35. 2 from Taiwan viper (Vipera russelli formosensis). Eur J Biochem 209, 635 641.
36. Harrison RA, Oliver J, Hasson SS, Bharati K Theakston RD (2003) Novel sequences encoding venom C-type lectins are conserved in phylogenetically and geographically distinct Echis and Bitis viper species. Gene 315, 95 102.
37. Tsai IH, Wang YM, Chiang TY, Chen YL Huang RJ (2000) Purification, cloning and sequence analyses for pro-metalloprotease-disintegrin variants from Deinagkistrodon acutus venom and subclassification of the small venom metalloproteases. Eur J Biochem 267, 1359 1367.
38. Dell A, Reason AJ, Khoo KH, Panico M, McDowell RA Morris HR (1994) Mass spectrometry of carbohydrate-containing biopolymers. Methods Enzymol 230, 108 132.
39. Ciucanu I Kerek F (1984) A simple and rapid method for the permethylation of carbohydrates. Carbohydr Res 131, 209 217.
40. Yu SY, Wu S Khoo KH (2006) Distinctive characteristics of MALDI-Q/TOF and TOF/TOF tandem mass spectrometry for sequencing of permethylated complex type N-glycans. Glycoconj J 23, 355 369.
41. Ritchie MA, Gill AC, Deery MJ Lilley K (2002) Precursor ion scanning for detection and structural characterization of heterogeneous glycopeptide mixtures. J Am Soc Mass Spectrom 13, 1065 1077.
42. Domon B Costello CE (1988) A systematic nomenclature for carbohydrate fragmentations in FAB-MS/MS spectra of glycoconjugates. Glycoconj J 5, 397 409.
43. Spina E, Sturiale L, Romeo D, Impallomeni G, Garozzo D, Waidelich D Glueckmann M (2004) New fragmentation mechanisms in matrix-assisted laser desorption/ionization time-of-flight/time-of-flighttandem mass spectrometry of carbohydrates. Rapid Commun Mass Spectrom 18, 392 398.