Hinokitiol, a natural tropolone derivative, inhibits TNF-α production in LPS-activated macrophages via suppression of NF-κB

Planta Medica

Volumn 74, Issue 8, 2008, Pages 828-833

  Byeon, Se Eun ^a   Lee, Yong Cyu ^a   Kim, Jin Chul ^a   Han, Jae Gun ^a   Lee, Hyeon Yong ^a   Cho, Jae Youl ^a  

^a Kangwon National University   (South Korea)

Author keywords

Hinokitiol; Intracellular signaling cascade; Macrophages; NF B; TNF

Indexed keywords

ESCHERICHIA COLI LIPOPOLYSACCHARIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PROTEIN KINASE B; THUJAPLICIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG ACTIVITY; DRUG EFFECT; ENZYME PHOSPHORYLATION; HAIR FOLLICLE; HAIR GROWTH; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; REPORTER GENE; SKIN INFLAMMATION;

ANTI-INFECTIVE AGENTS; CELL LINE; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; MACROPHAGES; MONOTERPENES; NF-KAPPA B; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TROPOLONE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 47249100745     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2008-1074548     Document Type: Article

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