Of mice and men, periodic limb movements and iron: How the human genome informs the mouse genome

Genes, Brain and Behavior

Volumn 7, Issue 5, 2008, Pages 513-514

  Jones, L C ^a   Earley, C J ^b   Allen, R P ^b   Jones, B C ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Btbd9; Bxd; Glo1; Iron; Qtl

Indexed keywords

IRON;

CHROMOSOME; GENE EXPRESSION; GENOME; HOMEOSTASIS; HUMAN; LIMB MOVEMENT; NONHUMAN; NOTE; PRIORITY JOURNAL; RESTLESS LEGS SYNDROME; SINGLE NUCLEOTIDE POLYMORPHISM;

ANIMALS; GENOME, HUMAN; GENOMICS; HUMANS; IRON; MICE; RESTLESS LEGS SYNDROME; TRANSCRIPTION FACTORS;

MUS;

EID: 47249098326     PISSN: 16011848     EISSN: 1601183X     Source Type: Journal    
DOI: 10.1111/j.1601-183X.2008.00400.x     Document Type: Note

References (7)

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2. Beard, J.L. Connor, J.R 2003) Iron status and neural functioning. Annu Rev Nutr 23, 41 58.
3. Earley, C.J., B. Barker, P., Horska, A. Allen, R.P 2006) MRI-determined regional brain iron concentrations in early-and late-onset restless legs syndrome. Sleep Med 5, 458 461.
4. Jones, B.C., Reed, C.L., Hitzemann, R., Wiesinger, J.A., McCarthy, K.A., Buwen, J.P. Beard, J.L 2003) Quantitative genetic analysis of ventral midbrain and liver iron in BXD recombinant inbred mice. Nutr Neurosci 6, 369 77.
5. Jones, L.C., McCarthy, K.A., Beard, J.L., Keen, C.L. Jones, B.C 2006) Quantitative genetic analysis of brain copper and zinc in BXD recombinant inbred mice. Nutr Neurosci 9, 81 92.
6. Stefansson, H., Rye, D.B., Hicks, A. et al 2007) A genetic risk factor for periodic limb movements in sleep. N Eng J Med 357, 639 647.
7. Winkelmann, J., Schormair, B., Lichtner, P. et al 2007) Genome-wide association study of restless legs syndrome identifies common variants in three genomic regions. Nat Genet 39, 1000 1006.