3-Isobutylmethylxanthine inhibits hepatic urea synthesis: Protection by agmatine

Journal of Biological Chemistry

Volumn 283, Issue 22, 2008, Pages 15063-15071

  Nissim, Itzhak ^a,b   Horyn, Oksana ^a   Nissim, Ilana ^a   Daikhin, Yevgeny ^a   Wehrli, Suzanne L ^a   Yudkoff, Marc ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BINDING SITES; CHEMICAL REACTIONS; ENZYME INHIBITION; LIVER; METABOLISM; PHOSPHORYLATION; UREA;

ACTIVE SITES; AGMATINE; ATP SYNTHESIS; CASCADE EFFECTS; CITRULLINE; EXPERIMENTAL APPLICATIONS; INTERVENTION THERAPIES; LIVER PERFUSIONS; MITOCHONDRIAL RESPIRATORY CHAINS; OXIDATIVE PHOSPHORYLATIONS; PHOSPHODIESTERASE INHIBITORS; PILOT EXPERIMENTS; RAT LIVERS; RESPIRATORY CHAINS; SYNTHASE; UREA SYNTHESES;

FETAL MONITORING;

ADENOSINE TRIPHOSPHATE; AGMATINE; AMMONIUM CHLORIDE; CARBAMOYL PHOSPHATE SYNTHASE; CITRULLINE; CYCLIC AMP; GLUTAMINE; ISOBUTYLMETHYLXANTHINE; N ACETYLGLUTAMIC ACID; PHOSPHODIESTERASE INHIBITOR; UREA; PHOSPHODIESTERASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; LIVER CELL; LIVER METABOLISM; LIVER PERFUSION; MALE; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; PRIORITY JOURNAL; RAT; RESPIRATORY CHAIN; SIGNAL TRANSDUCTION; UREA CYCLE; ANIMAL; DRUG EFFECT; ELECTRON TRANSPORT; LIVER; LIVER MITOCHONDRION; METABOLISM; PERFUSION; SPRAGUE DAWLEY RAT;

RATTUS;

1-METHYL-3-ISOBUTYLXANTHINE; AGMATINE; ANIMALS; CARBAMOYL-PHOSPHATE SYNTHASE (AMMONIA); CYCLIC AMP; ELECTRON TRANSPORT; LIVER; MALE; MITOCHONDRIA, LIVER; OXYGEN CONSUMPTION; PERFUSION; PHOSPHODIESTERASE INHIBITORS; PHOSPHORIC DIESTER HYDROLASES; RATS; RATS, SPRAGUE-DAWLEY; UREA;

EID: 47249088366     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M800163200     Document Type: Article

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