Biological transformation, kinetics and dose-response assessments of bound musk ketone hemoglobin adducts in rainbow trout as biomarkers of environmental exposure

Journal of Environmental Sciences

Volumn 20, Issue 7, 2008, Pages 878-884

  MA, Mottaleb ^a   JH, Zimmerman ^b   TW, Moy ^b  

^a BAYLOR UNIVERSITY   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

biomarker; biotransformation; dose response; fish; hemoglobin adducts; kinetics; nitro musks

Indexed keywords

AMINES; AQUACULTURE; BIOCOMMUNICATIONS; BIOMOLECULES; CHROMATOGRAPHIC ANALYSIS; CONCENTRATION (PROCESS); FOOD ADDITIVES; GAS CHROMATOGRAPHY; HEMOGLOBIN; HEXANE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ION CHROMATOGRAPHY; IONIZATION OF GASES; IONIZATION OF LIQUIDS; KETONES; MASS SPECTROMETRY; METABOLITES; MUSKEG; ORGANIC COMPOUNDS; SIGNAL TO NOISE RATIO; STANDARDS;

2-AMINO; ADDUCT FORMATION; AQUATIC ORGANISM (FISH); BASIC HYDROLYSIS; BIOLOGICAL TRANSFORMATIONS; CHINESE ACADEMY OF SCIENCES (CAS); CONCENTRATION (COMPOSITION); CONTROL SAMPLES; DETECTION LIMIT (DL); DOSE RESPONSE STUDY; DOSE RESPONSES; ELECTRON-CAPTURE NEGATIVE ION (ECNI); ENVIRONMENTAL EXPOSURES; ENVIRONMENTAL SCIENCES; FIRST ORDER KINETICS; MASS SPECTRAL; METABOLITE CONCENTRATIONS; MUSK KETONE (MK); N-HEXANE; PERSONAL CARE PRODUCTS; RAINBOW TROUT (RT); RETENTION TIME (RT); SELECTED-ION-MONITORING (SIM); SIGNAL TO NOISE; SINGLE EXPOSURE;

EXTRACTION;

BIOLOGICAL MARKER; HEMOGLOBIN; MUSK KETONE; XYLENE;

AQUATIC ORGANISM; BIOMARKER; BIOTRANSFORMATION; DOSE-RESPONSE RELATIONSHIP; HEMOGLOBIN; KETONE; KINETICS; METABOLITE; POLLUTION EXPOSURE; SALMONID;

ANIMAL; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL MONITORING; METABOLISM; METHODOLOGY; RAINBOW TROUT; WATER POLLUTANT;

ANIMALS; BIOLOGICAL MARKERS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL MONITORING; HEMOGLOBINS; MOLECULAR STRUCTURE; ONCORHYNCHUS MYKISS; WATER POLLUTANTS, CHEMICAL; XYLENES;

ONCORHYNCHUS MYKISS; SALMONIDAE;

EID: 47149112794     PISSN: 10010742     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1001-0742(08)62141-5     Document Type: Article

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