Antioxidant plasma concentration and supplementation in carotid intima media thickness

Expert Review of Cardiovascular Therapy

Volumn 6, Issue 5, 2008, Pages 723-729

  Riccioni, Graziano ^a,b,c   Bazzano, Lydia A ^d  

^a SAN CAMILLO DE LELLIS HOSPITAL   (Italy)

^b UNIVERSITY OF CHIETI   (Italy)

^c Tulane University School of Public Health and Tropical Medicine ^*  (Italy)

^d TULANE UNIVERSITY   (United States)

Author keywords

Antioxidant vitamins; Carotid plaque; Intima media thickness; Oxidative stress; Supplementation

Indexed keywords

ALPHA CAROTENE; ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; BETA CAROTENE; BETA CRYPTOXANTHIN; CAROTENOID; LYCOPENE; PLACEBO; POLYPHENOL DERIVATIVE; PRAVASTATIN; REACTIVE OXYGEN METABOLITE; RETINOL; VITAMIN; XANTHOPHYLL; ZEAXANTHIN; BIOLOGICAL MARKER;

ANGIOGRAPHY; ANTIOXIDANT ACTIVITY; ARTERIAL WALL THICKNESS; ARTERY INTIMA PROLIFERATION; ATHEROSCLEROTIC PLAQUE; B SCAN; CARDIOVASCULAR RISK; CAROTID ARTERY OBSTRUCTION; CLINICAL TRIAL; COMPUTER ASSISTED TOMOGRAPHY; CORONARY ARTERY DISEASE; DIAGNOSTIC ACCURACY; DIET SUPPLEMENTATION; DISEASE COURSE; DNA DAMAGE; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; EXERCISE; EXTERNAL CAROTID ARTERY; FOOD COMPOSITION; FRUIT; GRAIN; HUMAN; INFLAMMATION; INTERNAL CAROTID ARTERY OCCLUSION; INTRAVASCULAR ULTRASOUND; ISCHEMIC HEART DISEASE; LIPID PEROXIDATION; MORTALITY; NUCLEAR MAGNETIC RESONANCE IMAGING; OXIDATIVE STRESS; PATHOPHYSIOLOGY; REVIEW; RISK ASSESSMENT; RISK FACTOR; RISK REDUCTION; SENSITIVITY AND SPECIFICITY; SMOKING CESSATION; TREATMENT DURATION; VEGETABLE; ARTERIOSCLEROSIS; BLOOD; CARDIOVASCULAR DISEASE; CAROTID ARTERY; ECHOGRAPHY; FEMALE; HOSPITALIZATION; INTIMA; MALE; METABOLISM; PATHOLOGY; PROGNOSIS; RANDOMIZED CONTROLLED TRIAL; TUNICA MEDIA;

ANTIOXIDANTS; ARTERIOSCLEROSIS; BIOLOGICAL MARKERS; CARDIOVASCULAR DISEASES; CAROTENOIDS; CAROTID ARTERIES; CAROTID STENOSIS; FEMALE; HUMANS; MALE; OXIDATIVE STRESS; PROGNOSIS; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RISK FACTORS; SENSITIVITY AND SPECIFICITY; SEVERITY OF ILLNESS INDEX; TUNICA INTIMA; TUNICA MEDIA; VITAMIN A; VITAMIN E;

EID: 47149106632     PISSN: 14779072     EISSN: 17448344     Source Type: Journal    
DOI: 10.1586/14779072.6.5.723     Document Type: Review

References (48)

1. Pearson TA. Cardiovascular disease in developing countries: myths, realities, and opportunities. Cardiovasc. Drug. Ther. 13, 94-104 (1999).
2. Vasan RS, Benjamin EJ, Sullivan LM et al. The burden of increasing worldwide cardiovascular disease. In: Hurst's The Heart, 11th Edition. Fuster C, Wayne AR, O'Rourke RA (Eds). McGraw-Hill, NY, USA, 15-36 (2004).
3. Neaton J, Wentworth D. Serum cholesterol, blood pressure, cigarette smoking, and death from coronary heart disease. Overall findings and difference by age for 316,099 white man. Arch. Intern. Med. 152, 56-64 (1992).
4. Rao AV, Rao GL. Carotenoid and human health. Pharmacol. Res. 55, 207-216 (2007).
5. Britton G. Structure and properties of carotenoids in relation to function. FASEB. J. 9, 1551-1558 (1999).
6. Riccioni G, Bucciarelli T, Mancini B et al. The role of the antioxidant vitamin supplementation in the prevention of cardiovascular diseases. Expert Opin. Investig. Drugs 16, 25-32 (2007).
7. Riccioni G, Bucciarelli T, Mancini B et al. Antioxidant vitamin supplementation in cardiovascular diseases. Ann. Clin. Lab. Sci. 37, 89-95 (2007).
8. Thomson MJ, Puntmann V, Kaski JC. Atherosclerosis and oxidant stress: the end of the road for antioxidant vitamin treatment? Cardiovasc. Drugs Ther. 21, 195-210 (2007).
9. Tardif JC. Antioxidants: the good, the bad and the ugly. Can. J. Cardiol. 22, 61-65 (2006).
10. Rodrigo R, Guichard C, Charles R. Clinical pharmacology and therapeutic use of antioxidant vitamins. Fundam. Clin. Pharmacol. 21, 111-127 (2007).
11. Bleys J, Miller ER 3rd, Pastor-Barriuso R et al. Vitamin-mineral supplementation and the progression of atherosclerosis: a meta-analysis of randomized controlled trials. Am. J. Clin. Nutr. 84, 880-887 (2006).
12. Dzau VJ, Antman EM, HR Black et al. The cardiovascular disease continuum validated: clinical evidences of improved patient outcomes. Part I: pathophysiology and clinical trial evidence (risk factors through stable coronary artery disease). Circulation 114, 2850-2870 (2006).
13. Dzau J. Tissue angiotensin and pathobiology of vascular disease: a unifying hypothesis. Hypertension 37, 1047-1052 (2001).
14. Halliwell B, Gutteridge JMC. Free Radicals in Biology and Medicine. Oxford University Press, NY, USA, 936 (1999).
15. Stocker R, Keaney JF Jr. Role of oxidative modifications in atherosclerosis. Physiol. Rev. 84, 1381-1478 (2004).
16. Finkel T, Holbrook NJ. Oxidants, oxidative stress and the biology of ageing. Nature 408, 239-247 (2000).
17. Finkel T. Oxidant signals and oxidative stress. Curr. Opin. Cell. Biol. 15, 247-254 (2003).
18. Halliwell B, Whiteman M. Measuring reactive species and oxidative damage in vivo and in cell culture: how should you do it and what do the results mean? Br. J. Pharmacol. 142, 231-255 (2004).
19. Dizdaroglu M, Jaruga P, Birincioglu M et al. Free radical induced damage to DNA: mechanisms and measurement. Free Radic. Biol. Med. 32, 1102-1115 (2002).
20. Halliwell B. Effect of diet on cancer development: is oxidative DNA damage a biomarker? Free Radic. Biol. Med. 32, 968-974 (2002).
21. Valko M, Izakovic M, Mazur M et al. Role of oxygen radicals in DNA damage and cancer incidence. Mol. Cell. Biochem. 266, 37-56 (2004).
22. Heller FR, Deshamps O, Hondekijn JC. LDL oxidation: therapeutic perspectives. Atherosclerosis 137, 25-31 (1998).
23. Pincemail J. Free radicals and antioxidants in human disease. In: Analysis of Free Radicals in Biological Systems. Favier AE, Cadet J, Kalyanaraman B, Fontecave M, Pierre JL (Eds). Basel, Birkhäuser Verlag, Germany 83-98 (1995).
24. Ames BN, Gold LS, Willett WC. Causes and prevention of cancer. Proc. Natl Acad. Sci. USA 92, 5258-5265 (1995).
25. Witztum JL. The oxidation hypothesis of atherosclerosis. Lancet 344, 793-795 (1995).
26. Halliwell B. Free radicals, antioxidants and human disease: curiosity, cause or consequence? Lancet 344, 721-724 (1994).
27. Halliwell B, Murcia MA, Chirico S et al. Free radicals and antioxidants in food and in vivo: what they do and how they work. Crit. Rev. Food Sci. Nutr. 35, 7-20 (1995).
28. Sies H, Stahl W. Vitamins E and C, β-carotene, and other carotenoids as antioxidants. Am. J. Clin. Nutr. 62, 1315S-1321S (1995).
29. Feri B. Natural Antioxidants in Human Health and Disease. Academic Press San Diego, CA, USA (1994).
30. World Cancer Research Fund/American Institute for Cancer Research. food, Nutrition and the Prevention of Cancer: a Global Perspective. Washington, DC, USA (1997).
31. Rimm EB, Stampfer MJ, Ascherio A et al. Vitamin E consumption and the risk of coronary heart disease in men. N. Engl. J. Med. 328, 1450-1456 (1993).
32. Gaziano JM, Manson JE, Branch LG et al. A prospective study of consumption of carotenoids in fruits and vegetables and decreased cardiovascular mortality in the elderly. Ann. Epidemiol. 5, 255-260 (1995).
33. D'Odorico A, Martines D, Kiechl S et al. High plasma levels of α- and β-carotene are associated with a lower risk of atherosclerosis. Results from the Bruneck study. Atherosclerosis 153, 231-239 (2000).
34. Iannuzzi A, Celentano E, Panico S et al. Dietary and circulating antioxidant vitamins in relation to carotid plaques in middle-aged women. Am. J. Clin. Nutr. 3, 582-587 (2002).
35. Dwyer JH, Paul-Labrador MJ, Fan J et al. Progression of carotid intima-media thickness and plasma antioxidants: the Los Angeles Atherosclerosis Study. Arterios. Thromb. Vasc. Biol. 24, 313-318 (2004).
36. McQuillan BM, Hung J, Beaby JP et al. Antioxidant vitamins and the risk of carotid atherosclerosis. The Perth Carotid Ultrasound Assessment Study (CUDAS). J. Am. Coll. Cardiol. 38, 1788-1794 (2001).
37. Iribarren C, Folsom AR, Jacobs DR Jr et al. Association of serun vitamin levels, LDL susceptibility to oxidation, and autoantibodies against MDA-LDL with carotid atherosclerosis. A case-control study. The ARIC Study Investigators. Atherosclerosis Risk in Communities. Arterioscler. Thromb. Vasc. Biol. 7, 1171-1177 (1997).
38. Polidori MC, Praticò D, Parente B et al. Elevated lipid peroxidation biomarkers and low antioxidant status in atherosclerosis patients with increased carotid or iliofemofal intima media thickness. J. Invest. Med. 55, 163-167 (2007).
39. Giannetti J, Perinelli R, Petrucci R et al. Inverse association between carotid intima-media thickness and the antioxidant lycopene in atherosclerosis. Am. Heart. J. 143, 467-474 (2002).
40. Bolton-Smith C, Woodward M, Tunstall-Pedoe H. The Scottish Heart Health Study. Dietary intake by food frequency questionnaire and odds ratios for coronary heart disease risk, II: the antioxidant vitamins and fibre. Eur. J. Clin. Nutr. 46, 85-93 (1992).
41. Rimm EB, Stampfer MJ, Ascherio A et al. Vitamin E consumption and the risk of coronary heart disease in men. N. Engl. J. Med. 328, 1450-1456 (1993).
42. Rissanen TH, Voutilainen S, Nyyssonen K et al. Serum lycopene concentration and carotid atherosclerosis: the Kuopio Ischaemic Heart Disease Risk Factor Study. Am J. Clin. Nutr. 77, 13-18 (2003).
43. Salonen JT, Nyyssönen K, Salonen R et al. Antioxidant Supplementation in Atherosclerosis Prevention (ASAP) study: a randomized trial of the effect of vitamins E and C on 3-year progression of carotid atherosclerosis. J. Intern. Med. 248, 377-386 (2000).
44. Salonen RM, Nyyssönen K, Kaikkonen J et al. Six-year effect of combined vitamin C and E supplementation on atherosclerotic progression: the Antioxidant Supplementation in Atherosclerosis Prevention (ASAP) Study. Circulation 107, 947-953 (2003).
45. Nanayakkara PW, van Guldener C, ter Wee PM et al. Effect of a treatment strategy consisting of pravastatin, vitamin E, and homocysteine lowering on carotid intima-media thickness, endothelial function, and renal function in patients with mild to moderate chronic kidney disease; results from the Anti-Oxidant Therapy in Chronic Renal Insufficiency (ATIC) Study. Arch. Intern. Med. 167, 1262-1270 (2007).
46. Magliano D, McNeil J, Branley P et al. The Melbourne Atherosclerosis Vitamin E Trial (MAVET): a study of high dose vitamin E in smokers. Eur. J. Cardiovasc. Prev. Rehabil. 13, 341-347 (2006).
47. Zureik M, Galan P, Bertrais S et al. Effects of long-term daily low-dose supplementation with antioxidant vitamins and minerals on structure and function of large arteries. Arterioscler. Thromb. Vasc. Biol. 24, 1485-1491 (2004).
48. Hodis HN, Mack WJ, LaBree L et al. α-tocopherol supplementation in healthy individuals reduces low-density lipoprotein oxidation but not atherosclerosis; the Vitamin E Atherosclerosis Prevention Study (VEAPS). Circulation 106, 1453-1459 (2002).