Preventive effects of edaravone, a free radical scavenger, on lipopolysaccharide-induced lung injury in mice

Respirology

Volumn 13, Issue 5, 2008, Pages 646-653

  Tajima, Shunji ^a,b   Soda, Manabu ^a   Bando, Masashi ^a   Enomoto, Munehiro ^a   Yamasawa, Hideaki ^a   Ohno, Shoji ^a   Takada, Toshinori ^b   Suzuki, Eiichi ^b   Gejyo, Fumitake ^b   Sugiyama, Yukihiko ^a  

^a JICHI MEDICAL UNIVERSITY   (Japan)

^b NIIGATA UNIVERSITY GRADUATE SCHOOL OF MEDICAL AND DENTAL SCIENCES   (Japan)

Author keywords

Acute lung injury; Edaravone; Free radical scavenger; LPS; Pro inflammatory cytokine; Reactive oxygen species

Indexed keywords

ALBUMIN; CHEMOKINE; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MACROPHAGE INFLAMMATORY PROTEIN 2; NORPHENAZONE; REACTIVE OXYGEN METABOLITE; SCAVENGER; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BAGG ALBINO MOUSE; CELL INFILTRATION; CELL STIMULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOSE RESPONSE; DOSE TIME EFFECT RELATION; DRUG DOSE COMPARISON; FEMALE; IN VITRO STUDY; IN VIVO STUDY; LUNG ALVEOLUS MACROPHAGE; LUNG INJURY; LUNG LAVAGE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL;

ACUTE LUNG INJURY; ANIMALS; ANTIPYRINE; CELL LINE; CHEMOKINE CXCL2; DISEASE MODELS, ANIMAL; FEMALE; FREE RADICAL SCAVENGERS; INTERLEUKIN-6; LIPID PEROXIDATION; LIPOPOLYSACCHARIDES; MACROPHAGES, ALVEOLAR; MICE; MICE, INBRED BALB C; OXIDATIVE STRESS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 47149093702     PISSN: 13237799     EISSN: 14401843     Source Type: Journal    
DOI: 10.1111/j.1440-1843.2008.01322.x     Document Type: Article

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