PIV-measured versus CFD-predicted flow dynamics in anatomically realistic cerebral aneurysm models

Journal of Biomechanical Engineering

Volumn 130, Issue 2, 2008, Pages

  Ford, Matthew D ^a,b,c   Nikolov, Hristo N ^a   Milner, Jaques S ^a   Lownie, Stephen P ^a,b   DeMont, Edwin M ^d   Kalata, Wojciech ^e   Loth, Francis ^e   Holdsworth, David W ^a,b   Steinman, David A ^a,b,c  

^a ROBARTS RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d ST FRANCIS XAVIER UNIVERSITY   (Canada)

^e 1120 Science and Engineering Offices   (United States)

Author keywords

Anatomic realism; Cerebral aneurysm; Computational fluid dynamics; Particle image velocimetry

Indexed keywords

BOUNDARY CONDITIONS; BOUNDARY VALUE PROBLEMS; BRAIN; COMPUTATIONAL FLUID DYNAMICS; COMPUTATIONAL GEOMETRY; COMPUTERIZED TOMOGRAPHY; FLOW RATE; FLUID DYNAMICS; FLUID MECHANICS; FORECASTING; HEMODYNAMICS; IMAGE SEGMENTATION; INDEPENDENT COMPONENT ANALYSIS; PATIENT TREATMENT; POLYMERS; SILICONES; VORTEX FLOW;

ANTERIOR-POSTERIOR (AP); BASILAR ARTERY; CARDIAC CYCLES; CEREBRAL ANEURYSMS; CFD SIMULATIONS; COMPUTATIONAL FLUID DYNAMICS (CFD) MODELING; COMPUTER-CONTROLLED; COUNTER-ROTATING VORTICES; FLOW DYNAMICS; FLOW LOOPS; FLOW THROUGH; IN VITRO MODELING; IN-VIVO; INTERNAL CAROTID ARTERY (ICA); MICRO CT; PARTICLE IMAGING VELOCIMETRY (PIV); PERIODIC FLOWS; SILICONE ELASTOMERS; SPATIAL DISTRIBUTIONS; STABLE VORTEX; VELOCITY FIELDS; VELOCITY VECTOR FIELDS; VIRTUAL ANGIOGRAPHY; VORTEX DYNAMICS; WAVEFORMS;

DYNAMICS;

ELASTOMER; SILICONE;

ANALYTIC METHOD; ANATOMY; ARTICLE; BASILAR ARTERY; BRAIN ARTERY ANEURYSM; BRAIN BLOOD FLOW; COMPUTATIONAL FLUID DYNAMICS; DIGITAL SUBTRACTION ANGIOGRAPHY; HEART CYCLE; HEMODYNAMICS; IN VIVO STUDY; INTERMETHOD COMPARISON; PARTICLE IMAGING VELOCIMETRY; PHANTOM; PROGNOSIS; RELIABILITY; SIMULATION; VALIDATION PROCESS; VIRTUAL REALITY; BIOLOGICAL MODEL; BLOOD FLOW VELOCITY; BRAIN ANGIOGRAPHY; BRAIN CIRCULATION; COMPUTER SIMULATION; HUMAN; INTRACRANIAL ANEURYSM; METHODOLOGY; PATHOPHYSIOLOGY; THREE DIMENSIONAL IMAGING;

BLOOD FLOW VELOCITY; CEREBRAL ANGIOGRAPHY; CEREBROVASCULAR CIRCULATION; COMPUTER SIMULATION; HUMANS; IMAGING, THREE-DIMENSIONAL; INTRACRANIAL ANEURYSM; MODELS, CARDIOVASCULAR;

EID: 47149083067     PISSN: 01480731     EISSN: None     Source Type: Journal    
DOI: 10.1115/1.2900724     Document Type: Article

References (45)

1. ISUIA Investigators, 1998, "Unruptured Intracranial Aneurysms - Risk of Rupture and Risks of Surgical Intervention," N. Engl. J. Med., 339, pp. 1725-1733.
2. Tummala, R. P., Baskaya, M. K., and Heros, R. C., 2005, "Contemporary Management of Incidental Intracranial Aneurysms," Neurosurg Focus, 18, pp. e9.
3. Molyneux, A., Kerr, R., Stratton, I., Sandercock, P., Clarke, M., Shrimpton, J., and Holman, R., 2002, "International Subarachnoid Aneurysm Trial (ISAT) of Neurosurgical Clipping Versus Endovascular Coiling in 2143 Patients With Ruptured Intracranial Aneurysms: A Randomised Trial," Lancet, 360, pp. 1267-1274.
4. Molyneux, A. J., Kerr, R. S., Yu, L. M., Clarke, M., Sneade, M., Yarnold, J. A., and Sandercock, P., 2005, "International Subarachnoid Aneurysm Trial (ISAT) of Neurosurgical Clipping Versus Endovascular Coiling in 2143 Patients With Ruptured Intracranial Aneurysms: A Randomised Comparison of Effects on Survival, Dependency, Seizures, Rebleeding, Subgroups, and Aneurysm Occlusion," Lancet, 366, pp. 809-817.
5. Asgari, S., Wanke, I., Schoch, B., and Stolke, D., 2003, "Recurrent Hemorrhage After Initially Complete Occlusion of Intracranial Aneurysms," Neurosurg. Rev., 26, pp. 269-274.
6. Kawanabe, Y., Sadato, A., Taki, W., and Hashimoto, N., 2001, "Endovascular Occlusion of Intracranial Aneurysms With Guglielmi Detachable Coils: Correlation Between Coil Packing Density and Coil Compaction," Acta Neurochir. Suppl. (Wien), 143, pp. 451-455.
7. Nagashima, H., Kobayashi, S., Tanaka, Y., and Hongo, K., 2004, "Endovascular Therapy Versus Surgical Clipping for Basilar Artery Bifurcation Aneurysm: Retrospective Analysis of 117 Cases," J. Neuropsychiatry Clin. Neurosci., 11, pp. 475-479.
8. Mantha, A., Karmonik, C., Benndorf, G., Strother, C., and Metcalfe, R., 2006, "Hemodynamics in a Cerebral Artery Before and After the Formation of an Aneurysm," AJNR Am. J. Neuroradiol., 27, pp. 1113-1118.
9. Steinman, D. A., Milner, J. S., Norley, C. J., Lownie, S. P., and Holdsworth, D. W., 2003, "Image-Based Computational Simulation of Flow Dynamics in a Giant Intracranial Aneurysm," AJNR Am. J. Neuroradiol., 24, pp. 559-566.
10. Shojima, M., Oshima, M., Takagi, K., Torii, R., Hayakawa, M., Katada, K., Morita, A., and Kirino, T., 2004, "Magnitude and Role of Wall Shear Stress on Cerebral Aneurysm: Computational Fluid Dynamic Study of 20 Middle Cerebral Artery Aneurysms," Stroke, 35, pp. 2500-2505.
11. Hassan, T., Timofeev, E. V., Saito, T., Shimizu, H., Ezura, M., Matsumoto, Y., Takayama, K., Tominaga, T., and Takahashi, A., 2005, "A Proposed Parent Vessel Geometry-Based Categorization of Saccular Intracranial Aneurysms: Computational Flow Dynamics Analysis of the Risk Factors for Lesion Rupture," J. Neurosurg., 103, pp. 662-680.
12. Jou, L. D., Wong, G., Dispensa, B., Lawton, M. T., Higashida, R. T., Young, W. L., and Saloner, D., 2005, "Correlation Between Lumenal Geometry Changes and Hemodynamics in Fusiform Intracranial Aneurysms," AJNR Am. J. Neuroradiol., 26, pp. 2357-2363.
13. Cebral, J. R., Castro, M. A., Appanaboyina, S., Putman, C. M., Millan, D., and Frangi, A. F., 2005, "Efficient Pipeline for Image-Based Patient-Specific Analysis of Cerebral Aneurysm Hemodynamics: Technique and Sensitivity," IEEE Trans. Med. Imaging, 24, pp. 457-467.
14. Cebral, J. R., Castro, M. A., Burgess, J. E., Pergolizzi, R. S., Sheridan, M. J., and Putman, C. M., 2005, "Characterization of Cerebral Aneurysms for Assessing Risk of Rupture by Using Patient-Specific Computational Hemodynamics Models," AJNR Am. J. Neuroradiol., 26, pp. 2550-2559.
15. Byun, H. S., and Rhee, K., 2004, "CFD Modeling of Blood Flow Following Coil Embolization of Aneurysms," Med. Eng. Phys., 26, pp. 755-761.
16. Groden, C., Laudan, J., Gatchell, S., and Zeumer, H., 2001, "Three-Dimensional Pulsatile Flow Simulation Before and After Endovascular Coil Embolization of a Terminal Cerebral Aneurysm," J. Cereb. Blood Flow Metab., 21, pp. 1464-1471.
17. Stuhne, G. R., and Steinman, D. A., 2004, "Finite-Element Modeling of the Hemodynamics of Stented Aneurysms," ASME J. Biomech. Eng., 126, pp. 382-387.
18. Aenis, M., Stancampiano, A. P., Wakhloo, A. K., and Lieber, B. B., 1997, "Modeling of Flow in a Straight Stented and Nonstented Side Wall Aneurysm Model," ASME J. Biomech. Eng., 119, pp. 206-212.
19. Cebral, J. R., and Lohner, R., 2005, "Efficient Simulation of Blood Flow Past Complex Endovascular Devices Using an Adaptive Embedding Technique," IEEE Trans. Med. Imaging, 24, pp. 468-476.
20. Ford, M. D., Stuhne, G. R., Nikolov, H. N., Habets, D. F., Lownie, S. P., Holdsworth, D. W., and Steinman, D. A., 2005, "Virtual Angiography for Visualization and Validation of Computational Models of Aneurysm Hemodynamics," IEEE Trans. Med. Imaging, 24, pp. 1586-1592.
21. Ford, M. D., Nikolov, H. N., Milner, J. S., Kalata, W., Loth, F., Lownie, S. P., Holdsworth, D. W., and Steinman, D. A., 2005, "In Vitro Validation of an Image-Based CFD Model of an Anatomically Realistic Cerebral Aneurysm," presented at ASME Summer Bioengineering Conference, Vail, Colorado.
22. Ferguson, G. G., 1970, "Turbulence in Human Intracranial Saccular Aneurysms," J. Neurosurg., 33, pp. 485-497.
23. Fahrig, R., Fox, A. J., Lownie, S., and Holdsworth, D. W., 1997, "Use of a C-Arm System to Generate True Three-Dimensional Computed Rotational Angiograms: Preliminary In Vitro and In Vivo Results," AJNR Am. J. Neuroradiol., 18, pp. 1507-1514.
24. Yedavalli, R. V., Loth, F., Yardimci, A., Pritchard, W. F., Oshinski, J. N., Sadler, L., Charbel, F., and Alperin, N., 2001, "Construction of a Physical Model of the Human Carotid Artery Based on In Vivo Magnetic Resonance Images," ASME J. Biomech. Eng., 123, pp. 372-376.
25. Wetzel, S. G., Ohta, M., Handa, A., Auer, J. M., Lylyk, P., Lovblad, K. O., Babic, D., and Rufenacht, D. A., 2005, "From Patient to Model: Stereolithographic Modeling of the Cerebral Vasculature Based on Rotational Angiography," AJNR Am. J. Neuroradiol., 26, pp. 1425-1427.
26. Knox, K., Kerber, C. W., Singel, S. A., Bailey, M. J., and Imbesi, S. G., 2005, "Stereolithographic Vascular Replicas From CT Scans: Choosing Treatment Strategies, Teaching, and Research From Live Patient Scan Data," AJNR Am. J. Neuroradiol., 26, pp. 1428-1431.
27. Ford, M. D., Alperin, N., Lee, S. H., Holdsworth, D. W., and Steinman, D. A., 2005, "Characterization of Volumetric Flow Rate Waveforms in the Normal Internal Carotid and Vertebral Arteries," Physiol. Meas, 26, pp. 477-488.
28. Frayne, R., Holdsworth, D. W., Gowman, L. M., Rickey, D. W., Drangova, M., Fenster, A., and Rutt, B. K., 1992, "Computer-Controlled Flow Simulator for MR Flow Studies," J. Magn. Reson Imaging, 2, pp. 605-612.
29. 1981, CRC Handbook of Chemistry and Physiscs, 61st ed., CRC, Boca Raton, FL.
30. Hopkins, L. N., Kelly, J. T., Wexler, A. S., and Prasad, A. K., 2000, "Particle Image Velocimetry Measurements in Complex Geometries," Exp. Fluids, 29, pp. 91-95.
31. Fahrig, R., Nikolov, H., Fox, A. J., and Holdsworth, D. W., 1999, "A Three-Dimensional Cerebrovascular Flow Phantom," Med. Phys., 26, pp. 1589-1599.
32. Antiga, L., Ene-Iordache, B., Caverni, L., Cornalba, G. P., and Remuzzi, A., 2002, "Geometric Reconstruction for Computational Mesh Generation of Arterial Bifurcations From CT Angiography," Comput. Med. Imaging Graph., 26, pp. 227-235.
33. Ethier, C. R., Prakash, S., Steinman, D. A., Leask, R. I., Couch, G. G., and Ojha, M., 2000, "Steady Flow Separation Patterns in a 45 Degree Junction," J. Fluid Mech., 411, pp. 1-38.
34. Minev, P. D., and Ethier, C. R., 1999, "A Characteristic/Finite Element Algorithm for the 3-D Navier-Stokes Equations Using Unstructured Grids," Comput. Methods Appl. Mech. Eng., 178, pp. 39-50.
35. Ethier, C. R., Steinman, D. A., and Ojha, M., 1999, Comparisons Between Computational Hemodynamics, Photochromic Dye Flow Visualization and Magnetic Resonance Velocimetry, WIT, Southhampton.
36. Steinman, D. A., Thomas, J. B., Ladak, H. M., Milner, J. S., Rutt, B. K., and Spence, J. D., 2002, "Reconstruction of Carotid Bifurcation Hemodynamics and Wall Thickness Using Computational Fluid Dynamics and MRI," Magn. Reson. Med., 47, pp. 149-159.
37. Acevedo-Bolton, G., Jou, L. D., Dispensa, B. P., Lawton, M. T., Higashida, R. T., Martin, A. J., Young, W. L., and Saloner, D., 2006, "Estimating the Hemodynamic Impact of Interventional Treatments of Aneurysms: Numerical Simulation With Experimental Validation: Technical Case Report," Neurosurgery, 59, pp. E429-E430.
38. Imbesi, S. G., and Kerber, C. W., 1999, "Analysis of Slipstream Flow in Two Ruptured Intracranial Cerebral Aneurysms," AJNR Am. J. Neuroradiol., 20, pp. 1703-1705.
39. Imbesi, S. G., and Kerber, C. W., 2001, "Analysis of Slipstream Flow in a Wide-Necked Basilar Artery Aneurysm: Evaluation of Potential Treatment Regimens," AJNR Am. J. Neuroradiol., 22, pp. 721-724.
40. Tateshima, S., Grinstead, J., Sinha, S., Nien, Y. L., Murayama, Y., Villablanca, J. P., Tanishita, K., and Vinuela, F., 2004, "Intraaneurysmal Flow Visualization by Using Phase-Contrast Magnetic Resonance Imaging: Feasibility Study Based on a Geometrically Realistic In Vitro Aneurysm Model," J. Neurosurg., 100, pp. 1041-1048.
41. Tateshima, S., Murayama, Y., Villablanca, J. P., Morino, T., Takahashi, H., Yamauchi, T., Tanishita, K., and Vinuela, F., 2001, "Intraaneurysmal Flow Dynamics Study Featuring an Acrylic Aneurysm Model Manufactured Using a Computerized Tomography Angiogram as a Mold," J. Neurosurg., 95, pp. 1020-1027.
42. Lieber, B. B., Livescu, V., Hopkins, L. N., and Wakhloo, A. K., 2002, "Particle Image Velocimetry Assessment of Stent Design Influence on Intra-Aneurysmal Flow," Ann. Biomed. Eng., 30, pp. 768-777.
43. Liou, T. M., Liou, S. N., and Chu, K. L., 2004, "Intra-Aneurysmal Flow With Helix and Mesh Stent Placement Across Side-Wall Aneurysm Pore of a Straight Parent Vessel," ASME J. Biomech. Eng., 126, pp. 36-43.
44. Hassan, T., Timofeev, E. V., Ezura, M., Saito, T., Takahashi, A., Takayama, K., and Yoshimoto, T., 2003, "Hemodynamic Analysis of an Adult Vein of Galen Aneurysm Malformation by Use of 3D Image-Based Computational Fluid Dynamics," AJNR Am. J. Neuroradiol., 24, pp. 1075-1082.
45. Valencia, A., and Zarate, A. Galvez, M., and Badilla, L., 2006, "Non-Newtonian Blood Flow Dynamics in a Right Internal Carotid Artery with a Saccular Aneurysm," Int. J. Numer. Methods Fluids, 50, pp. 751-764.