Association of blood pressure and genetic background with white matter lesions in patients with mild cognitive impairment

Journals of Gerontology - Series A Biological Sciences and Medical Sciences

Volumn 63, Issue 5, 2008, Pages 510-517

  Galluzzi, Samantha ^a   Geroldi, Cristina ^a   Benussi, Luisa ^a   Ghidoni, Roberta ^a   Testa, Cristina ^a   Borsci, Genoveffa ^a   Bonetti, Matteo ^c   Manfellotto, Dario ^a   Romanelli, Giuseppe ^b   Zulli, Roberto ^b   Binetti, Giuliano ^a   Frisoni, Giovanni B ^a  

^a IRCCS ISTITUTO CENTRO SAN GIOVANNI DI DIO FATEBENEFRATELLI   (Italy)

^b UNIVERSITY OF BRESCIA   (Italy)

^c Istituto Clinico Città di Brescia Hospital   (Italy)

Author keywords

Blood pressure; Cystatin c; Genotype; Mild cognitive impairment; White matter lesions

Indexed keywords

APOLIPOPROTEIN E; CHOLESTEROL 24 HYDROXYLASE; CYSTATIN C; OXYGENASE; UNCLASSIFIED DRUG;

AGED; ALLELE; ARTICLE; BLOOD PRESSURE FLUCTUATION; BLOOD PRESSURE MONITORING; BLOOD VESSEL INJURY; BRAIN DAMAGE; CEREBROVASCULAR DISEASE; COGNITIVE DEFECT; CONTROLLED STUDY; DISEASE SEVERITY; DNA POLYMORPHISM; FEMALE; GENETIC PREDISPOSITION; HUMAN; MALE; NUCLEAR MAGNETIC RESONANCE; PREVALENCE; PRIORITY JOURNAL; RISK FACTOR; SYSTOLIC BLOOD PRESSURE; WHITE MATTER; BLOOD PRESSURE; BRAIN; GENETICS; HOSPITALIZATION; PATHOLOGY; PATHOPHYSIOLOGY;

AGED; BLOOD PRESSURE; BRAIN; COGNITION DISORDERS; FEMALE; HUMANS; MALE; SEVERITY OF ILLNESS INDEX;

EID: 47049129750     PISSN: 10795006     EISSN: None     Source Type: Journal    
DOI: 10.1093/gerona/63.5.510     Document Type: Article

References (42)

1. Morris JC, Storandt M, Miller JP, et al. Mild cognitive impairment represents early-stage Alzheimer disease. Arch Neurol. 2001;58:397-405.
2. DeCarli C, Miller BL, Swan GE, Reed T, Wolf PA, Carmelli D. Cerebrovascular and brain morphologic correlates of mild cognitive impairment in the National Heart, Lung, and Blood Institute Twin Study. Arch Neurol. 2001;58:643-647.
3. Frisoni GB, Galluzzi S, Bresciani L, Zanetti O, Geroldi C. Mild cognitive impairment with subcortical vascular features: clinical characteristics and outcome. J Neurol. 2002;249:1423-1432.
4. Breteler MM, van Swieten JC, Bots ML, et al. Cerebral white matter lesions, vascular risk factors, and cognitive function in a population-based study: the Rotterdam Study. Neurology. 1994;44:1246-1252.
5. De Leeuw FE, Barkhof F, Scheltens P. Alzheimer's disease - one clinical syndrome, two radiological expressions: a study on blood pressure. J Neurol Neurosurg Psychiatry. 2004;75:1270-1274.
6. O'Rourke MF, Safar ME. Relationship between aortic stiffening and microvascular disease in brain and kidney: cause and logic of therapy. Hypertension. 2005;46:200-204.
7. de Leeuw FE, de Groot JC, Oudkerk M, et al. Hypertension and cerebral white matter lesions in a prospective cohort study. Brain. 2002;125:765-772.
8. Sierra C, de La Sierra A, Mercader J, Gomez-Angelats E, Urbano-Marquez A, Coca A. Silent cerebral white matter lesions in middle-aged essential hypertensive patients. J Hypertens. 2002;20:519-524.
9. Yamamoto Y, Akiguchi I, Oiwa K, Hayashi M, Ohara T, Ozasa K. The relationship between 24-hour blood pressure readings, subcortical ischemic lesions and vascular dementia. Cerebrovasc Dis. 2005;19:302-308.
10. Kukla C, Sander D, Schwarze J, Wittich I, Klingelhofer J. Changes of circadian blood pressure patterns are associated with the occurrence of lacunar infarction. Arch Neurol. 1998;55:683-688.
11. Sander D, Winbeck K, Klingelhofer J, Conrad B. Extent of cerebral white matter lesions is related to changes of circadian blood pressure rhythmicity. Arch Neurol. 2000;57:1302-1307.
12. van Boxtel MP, Henskens LH, Kroon AA, et al. Ambulatory blood pressure, asymptomatic cerebrovascular damage and cognitive function in essential hypertension. J Human Hypertens. 2006;20:5-13.
13. Chabriat H, Vahedi K, Iba-Zizen MT, et al. Clinical spectrum of CADASIL: a study of 7 families. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy. Lancet. 1995;346:934-939.
14. Natte R, Maat-Schieman ML, Haan J, Bornebroek M, Roos RA, van Duinen SG. Dementia in hereditary cerebral hemorrhage with amyloidosis-Dutch type is associated with cerebral amyloid angiopathy but is independent of plaques and neurofibrillary tangles. Ann Neurol. 2001;50:765-772.
15. Atwood LD, Wolf PA, Heard-Costa NL, et al. Genetic variation in white matter hyperintensity volume in the Framingham Study. Stroke. 2004;35:1609-1613.
16. Tian J, Shi J, Bailey K, Lendon CL, Pickering-Brown SM, Mann DM. Association between apolipoprotein E e4 allele and arteriosclerosis, cerebral amyloid angiopathy, and cerebral white matter damage in Alzheimer's disease. J Neurol Neurosurg Psychiatry. 2004;75:696-699.
17. Wen HM, Baum L, Cheung WS, et al. Apolipoprotein E epsilon4 allele is associated with the volume of white matter changes in patients with lacunar infarcts. Eur J Neurol. 2006;13:1216-1220.
18. Doody RS, Azher SN, Haykal HA, Dunn JK, Liao T, Schneider L. Does APO epsilon4 correlate with MRI changes in Alzheimer's disease? J Neurol Neurosurg Psychiatry. 2000;69:668-671.
19. Kuller LH, Shemanski L, Manolio T, et al. Relationship between ApoE, MRI findings, and cognitive function in the Cardiovascular Health Study. Stroke. 1998;29:388-398.
20. Babiloni C, Benussi L, Binetti G, et al. Genotype (cystatin C) and EEG phenotype in Alzheimer disease and mild cognitive impairment: a multicentric study. Neuroimage. 2006;29:948-964.
21. Levy E, Jaskolski M, Grubb A. The role of cystatin C in cerebral amyloid angiopathy and stroke: cell biology and animal models. Brain Pathol. 2006;16:60-70.
22. Haan J, Maat-Schieman ML, Roos RA. Clinical aspects of cerebral amyloid angiopathy. Dementia. 1994;5:210-213.
23. Papassotiropoulos A, Streffer JR, Tsolaki M, et al. Increased brain beta-amyloid load, phosphorylated tau, and risk of Alzheimer disease associated with an intronic CYP46 polymorphism. Arch Neurol. 2003;60:29-35.
24. Folstein MF, Folstein SE, McHugh PR. "ental State." practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975;12:189-198.
25. Shulman KI. Clock-drawing: is it the ideal cognitive screening test? Int J Geriatr Psychiatry. 2000;15:548-561.
26. Rossi R, Geroldi C, Bresciani L, et al. Clinical and neuropsychological features associated with structural imaging patterns in patients with mild cognitive impairment. Dement Geriatr Cogn Disord. 2007;23:175-183.
27. O'Brien E, Coats A, Owens P, et al. Use and interpretation of ambulatory blood pressure monitoring: recommendations of the British hypertension society. BMJ. 2000;320:1128-1134.
28. Nordic Council on Medicines. Guidelines for ATC Classification. Oslo: WHO Collaborating Centre for Drug Statistics Methodology; 1990.
29. Mancia G, Bombelli M, Lanzarotti A, et al. Systolic vs diastolic blood pressure control in the hypertensive patients of the PAMELA population. Pressioni Arteriose Monitorate E Loro Associazioni. Arch Intern Med. 2002;162:582-586.
30. Wahlund LO, Barkhof F, Fazekas F, et al. European Task Force on Age-Related White Matter Changes. A new rating scale for age-related white matter changes applicable to MRI and CT. Stroke. 2001;32:1318-1322.
31. Hixson JE, Vernier DT. Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI. J Lipid Res. 1990;31:545-548.
32. Finckh U, von der Kammer H, Velden J, et al. Genetic association of a cystatin C gene polymorphism with late-onset Alzheimer disease. Arch Neurol. 2000;57:1579-1583.
33. Benussi L, Ghidoni R, Steinhoff T, et al. Alzheimer disease-associated cystatin C variant undergoes impaired secretion. Neurobiol Dis. 2003;13:15-21.
34. Fazekas F, Kleinert R, Offenbacher H, et al. Pathologic correlates of incidental MRI white matter signal hyperintensities. Neurology. 1993;43:1683-1689.
35. Schmidt R, Enzinger C, Ropele S, Schmidt H, Fazekas F. Austrian Stroke Prevention Study. Progression of cerebral white matter lesions: 6-year results of the Austrian Stroke Prevention Study. Lancet. 2003;361:2046-2048.
36. Enzinger C, Smith S, Fazekas F, et al. Lesion probability maps of white matter hyperintensities in elderly individuals: results of the Austrian stroke prevention study. J Neurol. 2006;253:1064-1070.
37. Pantoni L. Pathophysiology of age-related cerebral white matter changes. Cerebrovasc Dis. 2002;13Suppl 2:7-10.
38. Sander D, Winbeck K, Klingelhofer J, Conrad B. Extent of cerebral white matter lesions is related to changes of circadian blood pressure rhythmicity. Arch Neurol. 2000;57:1302-1307.
39. Gomez-Angelats E, de La Sierra A, Sierra C, Parati G, Mancia G, Coca A. Blood pressure variability and silent cerebral damage in essential hypertension. Am J Hypertens. 2004;17:696-700.
40. Hoshi T, Kitagawa K, Yamagami H, Furukado S, Hougaku H, Hori M. Relations of serum high-sensitivity C-reactive protein and interleukin-6 levels with silent brain infarction. Stroke. 2005;36:768-772.
41. van Dijk EJ, Prins ND, Vermeer SE, et al. C-reactive protein and cerebral small-vessel disease: the Rotterdam Scan Study. Circulation. 2005;112:900-905.
42. O'Sullivan M, Morris RG, Huckstep B, Jones DK, Williams SC, Markus HS. Diffusion tensor MRI correlates with executive dysfunction in patients with ischaemic leukoaraiosis. J Neurol Neurosurg Psychiatry. 2004;75:441-447.